Clinical trials: ACL
Anterior Cruciate Ligament Injury
The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruction
The overall aim of this study is to determine the effect of the knee flexion angle (KFA) of either 0 degrees, or 30 degrees (measured by sterile goniometer) during anterior cruciate ligament (ACL) fixation on postoperative…
- Trial name
- KFA-FIRM (NCT03875807)
- Testing
- ACLR done at 0 degrees KFA, ACLR done at 30 degrees KFA
- Volunteers
- 204 people
- Sponsor
- Women's College Hospital
ACL Injury, Anterior Cruciate Ligament Injuries
Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes
The purpose of this research is to find out whether the way information about surgery is presented to patients affects patient satisfaction, knowledge retention, and surgical outcomes such as anxiety
- Trial name
- NCT05273463
- Testing
- Video-Based Intervention, Classroom-Based Intervention
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Injury
Functional Resistance Training to Improve Knee Function After ACL Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury and reconstruction can be improved with functional resistance training.
- Trial name
- NCT03282565
- Testing
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
ACL - Anterior Cruciate Ligament Deficiency, Muscle Weakness
Isokinetic Muscular Assessment After ACL Ligamentoplasty: Study of Factors Predictive of Muscle Imbalance.
Despite advances in surgery and rehabilitation, the return to sport after anterior cruciate ligament (ACL) reconstruction surgery remains a major challenge. challenge.
- Trial name
- PREDICT-ACL (NCT04071912)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Caen
ACL Injury
Can a Strength and Technique Intervention Reduce Knee Abduction Moment in Young Female Handball Players
Anterior cruciate ligament (ACL) injury constitutes the largest problem in female elite ball/team sport today, due to its relatively high incidence and serious short- and long-term consequences.
- Trial name
- NCT05643261
- Testing
- Muscle and technique training
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Norges idrettshøgskole
Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament (ACL) Reconstruction- Bioabsorbable Screw
To evaluate the knee functionality, screw integrity, graft integrity, cartilage effect, and bony ingrowth in patients treated with the CALAXO screw and MILAGRO screw two years after ACL reconstruction.
- Trial name
- NCT01069588
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Injury
A Novel Analgesia Technique for ACL Reconstruction
A comparison of two anesthetic techniques-- the Adductor Canal Block (ACB) and the Adductor Canal Block with Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (ACB/IPACK)-- in…
- Trial name
- NCT03292926
- Testing
- Bupivacaine, Ultrasound, Dexamethasone
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Hospital for Special Surgery, New York
ACL-injury
Comparison of Low-Level Laser Therapy Versus Infrared Therapy in Grade II ACL Injury Rehabilitation
This study is being conducted to compare two commonly used physical therapy treatments, low-level laser therapy (LLLT) and infrared therapy, for people with a Grade II anterior cruciate ligament (ACL) injury of the knee.
- Trial name
- NCT07829835
- Testing
- Low-Level Laser Therapy (LLLT), Infrared Therapy (IRT), Standard Physiotherapy
- Where
- 3 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Superior University
Anterior Cruciate Ligament (ACL) Tear
Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents
The purpose of this research is to compare the effect of single-injection sciatic PNB to continuous sciatic PNB on 1) postoperative pain control as measured by self-reported pain scores, pain medication use, and unplanned…
- Trial name
- NCT02947633
- Testing
- Single-injection sciatic PNB, Continuous sciatic PNB
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament (ACL)
Prospective Cohort Study of Villarreal CF Youth Players
Anterior cruciate ligament (ACL) injuries represent a highly relevant issue in both grassroots and professional sports, with a particularly high incidence in young and female populations.
- Trial name
- VILLAREALFC (NCT07653633)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Cardenal Herrera University
Knee Injuries
Non- vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or…
- Trial name
- NCT05073276
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
ACL Surgery, ACL Injuries
Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale
Psychological factors play a critical role in recovery following anterior cruciate ligament (ACL) reconstruction. While tools such as the ACL - Return to Sport after Injury (ACL-RSI) focus on psychological readiness, emphasizing…
- Conditions
- ACL Surgery, ACL Injuries, ACL Reconstruction
- Trial name
- RISE-ACL (NCT06748066)
- Testing
- RISE-ACL development, RISE-ACL scale validation
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears
Although the success of physical therapy following surgery has been well-documented and validated in patients undergoing Anterior Cruciate Ligament Reconstruction (ACLR) procedures, more recent studies have demonstrated that…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04593264
- Testing
- Self-guided pre-habilitation exercise program, Traditional pre-habilitation
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- WellSpan Health
Leg Injuries
Neuromuscular Training to Reduce Sports Injuries Among Children and Adolescents
Sports-related injuries are a serious concern for physically active children and adolescents. Previous research, including ours at Chicago public high schools, shows our neuromuscular training program, the Knee Injury Prevention…
- Trial name
- KIPP (NCT01406054)
- Testing
- neuromuscular exercises
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
ACL Injury
BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
The overall objective of the proposed research is to conduct a prospective, randomized controlled trial to investigate whether the addition of BFR therapy to standard post-operative rehabilitation regimen significantly improves…
- Trial name
- NCT04519801
- Testing
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brooke Army Medical Center
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
ACL Reconstruction
A Multi-centre, Double-blind RCT to Investigate the Effect of Alendronate on Knee Function Following ACLR
Anterior cruciate ligament (ACL) is the key ligament connecting the femur to tibia that helps stabilising the knee joint. ACL tear is common.
- Trial name
- NCT05527548
- Testing
- Alendronate (ALN)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen