Clinical trials: ACL Injuries
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
PRP in ACLR to Prevent PTOA
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
- Trial name
- NCT05412381
- Testing
- platelet rich plasma (PRP) injection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injury
Virtual Reality Mindfulness Meditation After ACL Reconstruction
To evaluate the effect of virtual reality mindfulness meditation on patients after ACLR, the investigators will determine the effect of virtual reality mindfulness meditation to 1) decrease self-reported injury-related fear, 2)…
- Trial name
- NCT05527171
- Testing
- Virtual Reality Mindfulness Meditation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
Knee Injuries
Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing fibular collateral ligament (FCL) reconstruction alone or combined FCL and anterior cruciate ligament (ACL) reconstructions…
- Trial name
- NCT05073263
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
ACL Injury
Effectiveness of a Novel Warm-up in Decreasing Risk Factors for ACL Injury in Female Youth Soccer Players
There is a large number of young women who sustain serious knee injuries from playing soccer. Female athletes are at high risk of knee injuries from soccer than males.
- Trial name
- NCT01591941
- Testing
- Core-PAC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Knee Injury
Dynamic Stability of the Anterior Cruciate Ligament (ACL) Deficient Knee
The study that is registered in ClinicalTrials is a part study of an overall study with the title 'Dynamic stability of the ACL-injured knee'.
- Trial name
- NCT00696319
- Testing
- Exercise protocol with perturbation exercises., Exercise protocol with traditional exercises for stability and balance.
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Ullevaal University Hospital
ACL Injury
Real-time Sensorimotor Feedback for Injury Prevention in Males Assessed in Virtual Reality
Even though females are 2- to 10-times more likely to suffer an anterior cruciate ligament (ACL) injury, males represent the largest population of total ACL injuries.
- Trial name
- MaNMT (NCT04068701)
- Testing
- MaNMT Biofeedback
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Anterior Cruciate Ligament Tear
IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament…
- Trial name
- NCT03983941
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sujana Dontukurthy
Rupture of Anterior Cruciate Ligament
Study of the Anatomical Direct Insertion Anterior Cruciate Ligament Reconstruction
The purpose of the study is to study the effect of anatomical direct insertion ACL reconstruction compared with conventional anatomical ACL reconstruction.
- Trial name
- NCT02833454
- Testing
- direct insertion anterior cruciate ligament reconstruction, single bundle anterior cruciate ligament reconstruction, double bundle anterior cruciate ligament reconstruction
- Volunteers
- 320 people
- Sponsor
- Peking University Third Hospital
ACL Tear
Quadriceps Strengthening ACL Reconstruction
The purpose of this study is to characterize quadriceps function and squat biomechanics during the early strengthening phase in adolescent patients undergoing a standardized combined neuromuscular electrical stimulation (NMES)…
- Trial name
- ACL (NCT07015541)
- Testing
- NMES and BFR, Standard physical therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Anterior Cruciate Ligament Injury
The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruction
The purpose of this study is to conduct a randomized controlled trial to determine if the knee flexion angle (KFA) during anterior cruciate ligament reconstruction (ACLR) graft fixation has an effect on postoperative outcomes.
- Trial name
- FIRM (NCT02111759)
- Testing
- knee flexion angle 1, knee flexion angle 2
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- University of Toronto Orthopaedic Sports Medicine
Depression, Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
The goal of this parallel arm prospective randomized control trial study is to compare outcomes in Anterior Cruciate Ligament Reconstruction (ACLR) Surgery patients after exposure to a virtual psychological intervention (VPI)…
- Conditions
- Depression, Anterior Cruciate Ligament Injuries, Mental Health Issue
- Trial name
- NCT05965310
- Testing
- Virtual Psychological Intervention: Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Injury
The Effects of Neuromuscular Exercise Training on Core Stability and Hip Strength in Healthy Adolescent Females
This study is an evaluation of the effects of a Neuromuscular training program on hip strength and core stability. It is a randomized clinical trial evaluating pre and post scores.
- Trial name
- NME hip/core (NCT03012711)
- Testing
- Neuromuscular exercise training
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anterior Cruciate Ligament Injuries, Injuries, Knee
Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male.
- Conditions
- Anterior Cruciate Ligament Injuries, Injuries, Knee, Prevention & Control
- Trial name
- NCT04062578
- Testing
- Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Anterior Cruciate Ligament Rupture
Effect of Tunnel Placements on Clinical and MRI Findings Two Years After ACL Reconstruction With DB Technique
Purpose: To find out whether the clinical and MRI findings two years after anterior cruciate ligament (ACL) reconstruction were associated with each other so that MRI-based graft invisibility in the anteromedial (AM) graft would…
- Trial name
- NCT02000258
- Testing
- Double-bundle ACL reconstruction, Magnetic resonance imaging (MRI)
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Anterior Cruciate Ligament Injury
Effect of Tourniquet Use on the Pivot Shift Test
This prospective study will evaluate whether tourniquet inflation affects the results of the pivot shift test in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07831941
- Testing
- Thigh Tourniquet Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Umraniye Education and Research Hospital
Anterior Cruciate Ligament Injuries
Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction
To evaluate the effect of graded exposure and mindfulness meditation after ACLR, the investigators will determine the effect of graded exposure and mindfulness meditation to 1) decrease self-reported injury-related fear and…
- Trial name
- NCT05949177
- Testing
- Graded Exposure and Mindfulness Meditation, Waitlist Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Intraoperative Musculoskeletal Injury
Intraoperative Laxity Assessment of ACL Reconstruction, ACL Revision and MAT
Intraoperative knee laxity evaluation of patiente undergoing ACL reconstruction, ACL revision, MAT
- Trial name
- INTRA_KIN (NCT03441165)
- Testing
- ligament reconstruction and meniscus transplantation
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injury
Electrical Stimulation and Eccentric Exercise for Anterior Cruciate Ligament (ACL) Injury
Quadriceps muscle weakness is a common consequence of ACL injury. This muscle weakness is considered to result from neural inhibition preventing full muscle contraction and is referred to as arthrogenic muscle inhibition (AMI).
- Trial name
- NCT01555567
- Testing
- Electrical Stimulation, Eccentric Exercise
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Rupture
Allogeneic Bone-patellar Tendon-bone Transplantation
Objective To investigate the mid-term clinical effect of bone-patellar tendon-bone (BPTB) graft double-bundle reconstruction of the anterior cruciate ligament (ACL) of the knee joint under arthroscope.
- Trial name
- NCT04951531
- Testing
- BPTB double-bundle allograft, BPTB single-bundle allograft group, BPTB single-bundle autograft group
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking University Third Hospital