Clinical trials: ACL Tear
Patellar Dislocation, ACL Injury
The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) .
- Conditions
- Patellar Dislocation, ACL Injury, Meniscus Lesion, Trochlear Dysplasia
- Trial name
- FKC (NCT04607538)
- Testing
- No intervention is made
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Anterior Cruciate Ligament Rupture, Ligament Knee Injury
Combined Intra- and Extra-articular ACL Reconstruction Versus Isolated Intra-articular ACL Reconstruction
Abstract Introduction: Autologous hamstring tendons are the most commonly used grafts in ACL reconstruction worldwide. There are several ways to prepare the graft using these tendons.
- Trial name
- NCT06505525
- Testing
- Extra-articular reconstruction with the Anterolateral Ligament
- Where
- 2 sites in Brazil
- Volunteers
- 146 people
- Sponsor
- Federal University of São Paulo
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Cruciate Ligament Rupture
Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL…
- Trial name
- NCT02993679
- Testing
- reconstruction of the ACL and anterolateral ligament
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Anterior Cruciate Ligament Rupture
Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is surgery that is done to repair a damaged ligament in the knee. In this study we will look at whether the femoral nerve block, a commonly used method for pain relief after ACL…
- Trial name
- NCT00022854
- Testing
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Rupture
Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approac
The investigators designed a prospective randomized trial to evaluate whether an app based active muscle training program (GenuSport) can improve the postoperative strength by starting rehabilitation immediately after primary…
- Trial name
- NCT04224376
- Testing
- App based Serious Gaming with the Genu Sport knee trainer
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
ACL Tear
Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
The goal of this observational study is to compare patient outcomes for reconstructive surgery of ACL tears. This study utilizes two randomized groups, one being the control group that receives standard ACL reconstructive…
- Trial name
- BioACL (NCT05582226)
- Testing
- ACL reconstruction, Mesenchymal stem cell implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Andrews Research & Education Foundation
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair
Patients between 14-60 years of age who will undergo an anterior cruciate ligament (ACL) reconstruction between Nov 1, 2021- Dec 31, 2023, will have their charts reviewed be approached in clinic when the surgery is scheduled…
- Trial name
- NCT05494073
- Testing
- ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Rupture
Reconstruction of the ACL With QT Graft With Bone Plug vs BPTB
Background: Anterior cruciate ligament (ACL) injury is one of the most common orthopedic injuries worldwide. Currently, the use of the bone patellar tendon bone graft (BPTB) technique is considered the gold standard.
- Trial name
- NCT06189573
- Testing
- Anterior cruciate ligament Reconstruction with autologous quadriceps tendon graft, Anterior cruciate ligament Reconstruction with autologous bone patellar tendon bone graft
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Rehabilitacion
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Anterior Cruciate Ligament Rupture With Ligamentoplasty
Evaluation of the Evolution of Proprioceptive Reweighting Abilities Following Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) injury is the most common knee injury among athletes who play contact sports involving pivoting.
- Trial name
- ReproEVO (NCT07389850)
- Testing
- ReproEVO intervention
- Where
- 3 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Rupture of Anterior Cruciate Ligament
Study of Single And Double Bundle Anterior Cruciate Ligament (ACL) Graft Cross-sectional Dimensions
To study the difference between single and double bundle ACL graft cross-sectional dimensions compared with native ACL using postoperative 3-D MRI.
- Trial name
- NCT02834962
- Testing
- single bundle ACL reconstruction, double bundle ACL reconstruction
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction
Randomized control trial comparing two different Anterior Cruciate Ligament (ACL) grafts in Anterior Cruciate Ligament Reconstruction: the semitendinosus hamstrings graft and the quadriceps graft.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- SEQUAR (NCT04295148)
- Testing
- ACL Reconstruction with Semitendinosus graft, ACL Reconstruction with Quadriceps tendon-bone graft
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
ACL Reconstruction, Meniscus Tears
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
The goal of this clinical trial is to determine the effect of semiconductor sleeves on the treatment of Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) arthroscopic surgery.
- Conditions
- ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06979804
- Testing
- Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Illinois Center for Orthopaedic Research and Education
ACL Tears
Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction
Quantify differences in quadriceps function and gait biomechanics in individuals within 2 years of ACL reconstruction compared to a healthy comparison group and establish the feasibility of conducting a progressive strengthening…
- Trial name
- NCT03132987
- Testing
- Progressive strengthening program
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Creighton University
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Bridge-Enhanced ACL Restoration (BEAR) is a new procedure being developed to treat patients with ACL injuries. In the BEAR procedure, an implant is placed between the torn ends of the ACL and the patient's own blood is added to…
- Trial name
- NCT03348995
- Testing
- Bridge-Enhanced ACL Restoration (BEAR)
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- Miach Orthopaedics
Anterior Cruciate Ligament Rupture
Effect of Tunnel Placements on Clinical and MRI Findings Two Years After ACL Reconstruction With DB Technique
Purpose: To find out whether the clinical and MRI findings two years after anterior cruciate ligament (ACL) reconstruction were associated with each other so that MRI-based graft invisibility in the anteromedial (AM) graft would…
- Trial name
- NCT02000258
- Testing
- Double-bundle ACL reconstruction, Magnetic resonance imaging (MRI)
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Knee Injury, ACL Injury
Reducing Disparities in Knee Arthroscopy for Adolescents
Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can be delayed due to late recognition and barriers, such as insurance…
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino
- Trial name
- RED KARD (NCT07580625)
- Testing
- Educational program and patient navigator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anterior Cruciate Ligament Rupture
Cross Bracing Protocol Versus Surgery for Acute Anterior Cruciate Ligament Rupture
The aim of the EMBRACE clinical trial is to compare outcomes (knee pain, symptoms, function and quality of life) between people with anterior cruciate ligament (ACL) rupture who are managed with either a novel bracing protocol…
- Trial name
- EMBRACE (NCT06956339)
- Testing
- Early anterior cruciate ligament surgery, Novel bracing protocol
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- University of Melbourne