Clinical trials: ACP
Cerebral Palsy, Cerebral Palsy, Mixed
10-week Leucine Supplementation in Cerebral Palsy
The purpose of this study is to assess the effects of 10-weeks leucine supplementation on muscle growth, metabolism, body composition, inflammation and wellbeing in adolescents and young adults with CP.
- Conditions
- Cerebral Palsy, Cerebral Palsy, Mixed, Cerebral Palsy Ataxic
- Trial name
- NCT03668548
- Testing
- Leucine
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- St Mary's University College
Early Childhood Caries (ECC), Dental Caries
Effect Of Three Remineralizing Agents On Early Childhood Caries
Early Childhood Caries (ECC) remains a global public health concern, necessitating minimally invasive, fluoride-based alternatives to conventional restorative therapy.
- Trial name
- SDF (NCT07371117)
- Testing
- Silver Diamine Fluoride (SDF, 38%), Sodium Fluoride with CPP-ACP, Acidulated phospahate fluoride gel 1.23%
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Jazan
Orthodontic Appliance Complication, Tooth Demineralization
Fluoride Delivery to Prevent White Spots During Orthodontic Treatment
The aim of this 2-armed, parallel, randomised, controlled trial is to assess the effect of different ways of applying fluoride to teeth on the formation of white spots (enamel demineralisation), during orthodontic treatment with…
- Trial name
- FL4OWS (NCT05005689)
- Testing
- Fluoride mouthwash (0.05%; 225ppm)., Tooth Mousse Plus
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
White Spot Lesion of Tooth
Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions
to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.
- Trial name
- NCT03973554
- Testing
- pearl powder, CPP-ACP
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ruba Alaa El Din Adel El Damarisy
Dental Fluorosis
Resin Infiltration Versus Microabrasion With CPP-ACP for Fluorotic White Spot Lesions
Dental fluorosis can cause visible chalky-white spots on the front teeth. These white spot lesions may affect dental appearance even when the tooth surface is intact.
- Trial name
- NCT07704983
- Testing
- Resin infiltration, Enamel Microabrasion Plus CPP-ACP
- Where
- Vietnam
- Volunteers
- 42 people
- Sponsor
- Hue University of Medicine and Pharmacy
Ataxic Cerebral Palsy, Coordination and Balance Disturbances
Effects of Hand Arm Bimanual Intensive Therapy Including Lower Extremity on Balance and Coordination in Ataxic Cerebral Palsy
Ataxic cerebral palsy is an abnormal movement or posture pattern accompanied by a loss of coordinated muscle action, resulting in movements that lack proper force, rhythm, or accuracy.
- Trial name
- NCT06639802
- Testing
- Hand Arm Bimanual Intensive therapy including lower extremity (HABIT-ILE)
- Where
- Pakistan
- Volunteers
- 23 people
- Sponsor
- Foundation University Islamabad
Remineralization
Remineralization Effect of Fluoride Varnishes on Permanent Molars
The aim of this study was to evaluate and compare the efficacy of NaF, NaF with TCP, NaF with CPP-ACP, and NaF with CXP varnishes on newly erupted first permanent molar teeth.
- Trial name
- NCT04124887
- Testing
- Sodium Fluoride, Tricalcium Phosphate, Xylitol-coated calcium and phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Ataxic Cerebral Palsy
Efficacy of Virtual Reality on Balance in Children With Ataxic Cerebral Palsy Randomized Controlled Trail
Ataxic CP is one type of cerebral palsy. children with ataxic cerebral palsy have trouble with balance and coordination. They may walk with their legs farther apart than other kids and have a hard time with activities that use…
- Trial name
- NCT05411328
- Testing
- virtual reality
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Delta University for Science and Technology
Remineralization Effect of the Varnish on White Spot Lesions
Remineralization Potential of MI Varnish Versus Fluoride Varnish on White Spot Lesions in Maxillary Primary Incisors
Remineralization effect of CPP-ACP and Fluoride (MI varnish) versus Fluoride varnish on white spot lesions in maxillary primary incisors
- Trial name
- NCT03731403
- Testing
- MI varnish
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mutans Streptococci, Oral Health
Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children
This study is a randomized controlled trial involving 127 children ages between 4 and 5 years to investigate the efficacy of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in reducing Streptococcus mutans (S.
- Trial name
- NCT03526315
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Older Adults, Advance Care Planning
Motivational Interviewing to Enhance Advance Care Planning for Older Adults and Caregivers After Emergency Visits
This study aims to evaluate the effectiveness of a motivational interviewing (MI) intervention in enhancing advance care planning (ACP) among older adults who have visited the Emergency Room (ER) in the past six months and their…
- Conditions
- Older Adults, Advance Care Planning, Advance Directives, Family Members
- Trial name
- NCT06090240
- Testing
- Dyadic MI-ACP intervention, Elderly alone MI-ACP
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Ataxic Infantile Cerebral Palsy
Safety and Efficacy of Bone Marrow Derived Autologous Cells Treatment of Cerebral Palsy in Subjects Above 15 Years
This Study is Single arm, Single Centre trial to study the safety and efficacy of bone marrow derived autologous mononuclear cells (100 millions per dose)study enrollment duration 36 months sample size 100 patients should be…
- Trial name
- BMACCP (NCT01834664)
- Testing
- stem cell (MNCs )
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Ataxic Cerebral Palsy
Efficacy of Adding Lower Extremity Weights on Balance in Children With Ataxic Cerebral Palsy
Ataxic CP is one type of cerebral palsy. children with ataxic cerebral palsy have trouble with balance and coordination. They may walk with their legs farther apart than other kids and have a hard time with activities that use…
- Trial name
- NCT05227066
- Testing
- adding lower extremity weights, traditional physical therapy group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
White Spot Lesion, Orthodontic Appliance Complication
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
The goal of this randomized clinical trial is to compare the influence of casein phosphopeptide amorphous calcium phosphate (CPP-ACP), CPP-ACP in combination with fluoride (CPP-ACPF), high fluoride concentration, and conventional…
- Trial name
- NCT05710874
- Testing
- CPP-ACP paste, CPP-ACPF paste, 1.25% fluoride gel
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Caries
Modified Atraumatic Restorative Treatment Using CPP ACP
To evaluate the clinical and radiographic success of using Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) under glass ionomer restorations in atraumatic restorative treatment as a biomimetic approach in pediatric…
- Trial name
- NCT06098911
- Testing
- MI varnish
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effect of CPP-ACP Paste on Dental Caries in Primary Teeth
The purpose of this study is to determine if adding daily application of CPP-ACP containing paste for one year is superior to regular fluoride tooth brushing in preventing dental caries in high caries risk Thai preschool children.
- Trial name
- NCT01604109
- Testing
- 10 % w/v CPP-ACP paste, the paste without CPP-ACP
- Where
- Thailand
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Adamantinomatous Craniopharyngioma
Tocilizumab in Children With ACP
This study will be conducted in two phases. The first phase (phase 0) will be looking at patients with new or recurrent/ progressed craniopharyngioma tumors.
- Trial name
- NCT03970226
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Colorado, Denver
Cerebral Palsy (CP)
Proprioceptive Neuromuscular Facilitation Versus Music Therapy in Ataxic Cerebral Palsy
This study will recruit eligible participants from the Physical Therapy Department of the University of Lahore Teaching Hospital, obtain informed consent, and randomly assign them by lottery into two groups, with the assessor…
- Trial name
- NCT07278154
- Testing
- (PNF +Conventional physical therapy ), Music Therapy + Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- University of Lahore
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University