Clinical trials: AFib
Atrial Fibrillation, Left Atrial Appendage Closure
Left Atrial Appendage Closure With the LAmbre
The study was to retrospectively analyse the efficacy and safety of LAA closure using the LAmbre in our center from April 2014 to November 2015.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Stroke
- Trial name
- NCT03147391
- Testing
- LAA closure with LAmbre
- Volunteers
- 66 people
- Sponsor
- Shanghai 10th People's Hospital
Atrial Fibrillation
Analysis of Endocavitary Electrical Signal and Surface Electrocardiogram to Predict Ablation Outcome in Persistent Atrial Fibrillation
Background : Despite recent progress in the management of patients with Atrial Fibrillation (AF), AF remains one of the main risk factor of stroke, heart failure and cardiovascular mortality in the world.
- Trial name
- ASEPAF (NCT03937089)
- Testing
- Data collection
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Atrial Fibrillation
Screening for Silent Atrial Fibrillation During Influenza Vaccination
Silent atrial fibrillation is an important cause of unnecessary strokes. If diagnosed and treated in time with anticoagulants, many disabling strokes can be prevented.
- Trial name
- NCT02006524
- Testing
- 'MyDiagnostick
- Where
- Netherlands
- Volunteers
- 3,269 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Left Atrial Appendage Thrombi
Detection of Left Atrial Appendage (LAA) Thrombus: Comparison of Cardiac Magnetic Resonance Imaging and Transesophageal Echocardiogram
The purpose of this study is to compare Cardiac Magnetic Resonance (CMR) Imaging with transesophageal echocardiography (TEE) in detecting the presence of LAA thrombi in men and women with atrial fibrillation presenting for…
- Trial name
- NCT00797576
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Atrial Fibrillation
Cryoballoon Atrial Fibrillation Ablation Registry
This is a prospective registry of atrial fibrillation cryoablation in the Russian Federation. This study is observational, prospective, multicenter, open-label
- Trial name
- NCT03040037
- Where
- Russia
- Volunteers
- 1,100 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Atrial Fibrillation
Change of Heart Rate Variability and Baroreflex Sensitivity After Ventral Cardiac Denervation
Atrial fibrillation (Af) is the most common morbid event after open heart surgery. Its incidence ranges from 19% to 27%, as reported by the Society of Thoracic Surgeons database.
- Trial name
- NCT00190112
- Testing
- ventral cardiac denervation
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Atrial Fibrillation
Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation
This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation.
- Trial name
- NCT05190679
- Testing
- None/Observational Studies
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Vanderbilt University Medical Center
Non-valvular Atrial Fibrillation (NVAF), High Risk of Stroke
A Prospective, Single-arm Study Evaluating the Endothelialization Effect and Timeline of AnchorMan® Left Atrial Appendage Occluder in Non-valvular Atrial Fibrillation Patients at High Risk of Stroke
This study aims to evaluate the endotheliation efficacy of the AnchorMane® Left Atrial Appendage Occluder in non-valvular atrial fibrillation patients at high stroke risk.
- Trial name
- AnchorMan-NVAF (NCT07396493)
- Testing
- Intra-operative application of LAAC
- Volunteers
- 306 people
- Sponsor
- Shanghai Zhongshan Hospital
Persistent Atrial Fibrillation, Persistent Atrial Fibrillation Longstanding
Catheter Ablation of Advanced Forms of Atrial Fibrillation
The purpose of this study is to evaluate feasibility, safety, and efficacy of pulmonary vein isolation combined with posterior left atrial isolation and multiple linear lesions in both atria in patients with persistent and…
- Trial name
- ENDO MAZE (NCT07446244)
- Testing
- Endovascular ablation set mimicking cox maze 4 procedure.
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation, Paroxysmal Atrial Fibrillation
High-Power, Short-Duration Ablation in Treatment of Patients With Atrial Fibrillation
Atrial fibrillation (AF) stands as the most common type of cardiac arrhythmia. The frequency of AF in the overall population is 1-2%, with the incidence rate increasing with age from 0.5% in the 40-50 years old to 5-15% in those…
- Conditions
- Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
- Trial name
- HPSD (NCT06415149)
- Testing
- High power short duration ablation with 50 W, High power short duration ablation with 45 W
- Where
- Russia
- Volunteers
- 185 people
- Sponsor
- People's Friendship University of Russia
Paroxysmal Atrial Fibrillation
Effects of Mediyoga in Patients With Paroxysmal Atrial Fibrillation
The purpose of this study is to determinate if mediyoga has effects in quality of life, heart rate variability, blood pressure , heart rate in patients with paroxysmal atrial fibrillation (PAF).
- Trial name
- NCT01789372
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Danderyd Hospital
Atrial Fibrillation
Finnish AntiCoagulation in Atrial Fibrillation (FinACAF)
The aim of FINACAF study is to evaluate the incidence and risk of stroke, systemic thromboembolic events, myocardial infarction, major bleeding events, and mortality in relation to different attitudes regarding stroke prevention…
- Trial name
- FinACAF (NCT04645537)
- Volunteers
- 400,000 people
- Sponsor
- Helsinki University Central Hospital
Atrial Fibrillation and Flutter
Direct Oral Anticoagulants Pharmacodynamics in Octogenarian Patients With Atrial Fibrillation
Background: The incidence of atrial fibrillation(AF) increases substantially with age and it is estimated that more than one third of AF patients are octogenarians.
- Trial name
- NCT02623049
- Testing
- New oral anticoagulant pharmacodynamic analysis (blood level assesment)
- Where
- 2 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Rabin Medical Center
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Atrial Fibrillation
Cryoballoon Pulmonary Vein Isolation: Time-to-Isolation Dependent Freeze Protocols Comparison
The purpose of this study is to develop and prospectively test two Cryo-AF (atrial fibrillation) dosing protocols guided exclusively by time-to-isolation (TT-I) in patients undergoing a first-time Cryo-AF.
- Trial name
- NCT03854006
- Testing
- Cryoballoon pulmonary vein isolation
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Lodz
Atrial Fibrillation, Oral Anticoagulation
Management of Patients With Atrial Fibrillation Undergoing Coronary Artery Stenting
Treatment of patients suffering from atrial fibrillation pose problems when percutaneous coronary intervention with stent implantation (PCI-S) is performed.
- Conditions
- Atrial Fibrillation, Oral Anticoagulation, Percutaneous Coronary Intervention
- Trial name
- AFCAS (NCT00596570)
- Testing
- PCI
- Where
- Finland
- Volunteers
- 996 people
- Sponsor
- University of Turku
Anticoagulants, Compliance, Medication
Evaluating Medication Adherence to Novel Oral Anticoagulants With Anticoagulant Activity Monitoring in Patients With Atrial Fibrillation
The novel oral anticoagulants such as rivaroxaban, apixaban and dabigatran, specifically target either thrombin or factor Xa/IIa.
- Trial name
- NCT03666962
- Where
- 7 sites in China
- Volunteers
- 200 people
- Sponsor
- Cui Yimin
Paroxysmal Atrial Fibrillation
Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patient With Structural Heart Disease
The aim of this study is to study synergistic effect of eplerenone as Selective aldosterone receptor antagonist with amiodarone compared with amiodarone only in reducing recurrence of atrial fibrillation in patient with…
- Trial name
- NCT06168994
- Testing
- Eplerenone
- Volunteers
- 100 people
- Sponsor
- Assiut University
Atrial Fibrillation
The Effect of an Intervention Based on The CSM on Self-Management in Patients After Atrial Fibrillation Ablation
Aim The investigators will validate the feasibility and effectiveness of a self-management intervention program based on the Common-Sense Model of Self-Regulation for patients after atrial fibrillation ablation.
- Trial name
- NCT07741682
- Testing
- Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Intervention Group, Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Control Group
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Binzhou People's Hospital