Clinical trials: Absorption
Short Bowel Syndrome, Malabsorption
A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB
Children with inadequate intestinal absorption due to loss of large amounts of small bowel require intravenous nutrition (feeding through the vein) to sustain hydration and nutrition to avoid starvation and dehydration; however…
- Trial name
- NCT05635747
- Testing
- Relizorb Enzyme Cartridge
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Boston Children's Hospital
Short Bowel Syndrome, Malabsorption
A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB
Children with inadequate intestinal absorption due to loss of large amounts of small bowel require intravenous nutrition (feeding through the vein) to sustain hydration and nutrition to avoid starvation and dehydration; however…
- Trial name
- NCT03530852
- Testing
- Relizorb
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Boston Children's Hospital
Nutritional Deficiency
Zinc Bioavailability From Amaranth-enriched Maize Tortillas
Young children in Guatemala are at risk for nutrient deficiencies due to plant-based diets and poor sanitation. Stunting, frequent diarrhea, and respiratory infections are common.
- Trial name
- NCT02208609
- Testing
- Day 1: Maize Tortillas with 20% Amaranth, Day 2 Maize Tortillas without 20% Amaranth
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Onychomycosis
A Study of the Systemic Absorption of MOB015B
A Study of the Systemic Absorption of Once Daily MOB015B when Applied for 28 Days in Subjects with Moderate to Severe Onychomycosis of the Toenails.
- Trial name
- NCT03244280
- Testing
- MOB015B
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Moberg Pharma AB
Cystic Fibrosis
Imaging Airway Liquid Absorption in Cystic Fibrosis
The investigators are developing a new nuclear medicine imaging technique for measuring liquid absorption in the airways that can be applied to screen new medications being developed to treat cystic fibrosis (CF).
- Trial name
- NCT01486199
- Testing
- Absorptive clearance scan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Infection
Gastrointestinal Implications of Voriconazole Exposure
Voriconazole has better response rates, improved survival and less adverse side effects compared to other drugs for the treatment of invasive fungal infections making it a desirable therapeutic option for children.
- Trial name
- GIVE (NCT02904434)
- Testing
- Grapefruit Juice
- Where
- United States
- Sponsor
- Children's Hospital of Philadelphia
Iron Absorption
Iron Absorption in Vegetarian Children
Few areas are more controversial in pediatric nutrition than the role of a vegetarian diet for children. Advocates make strong health claims whereas others have expressed safety concerns, especially regarding iron nutrition.
- Trial name
- NCT01489007
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Linezolid Pharmacokinetics in Young Infants, Pharmacokinetic Analysis
Oral Antibiotic Pharmacokinetics in Young Infants
This observational study will characterize the pharmacokinetics of linezolid in young infants. Participants will receive linezolid either as part of routine clinical care or as a single, one-time study dose.
- Conditions
- Linezolid Pharmacokinetics in Young Infants, Pharmacokinetic Analysis, Linezolid, Infant and Young Children
- Trial name
- NCT07815613
- Testing
- Linezolid (LZD)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Acne
Absorption and Systematic Pharmacokinetics of IDP-123 Lotion in Comparison With Tazorac Cream
The Absorption and Systematic Pharmacokinetics of IDP-123 Lotion in Comparison with Tazorac Cream.
- Trial name
- NCT02849873
- Testing
- IDP-123 Lotion, Tazorac Cream
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Bausch Health Americas, Inc.
Neurogenic Detrusor Overactivity, Overactive Bladder
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron OCAS (Oral Controlled Absorption System) in Pediatric Subjects With Neurogenic Detrusor Overactivity or Overactive Bladder
The purpose of this study is to evaluate the pharmacokinetics as well as the safety and tolerability of mirabegron OCAS tablets after single-dose administration at different dose levels in children and adolescents with NDO or OAB.
- Conditions
- Neurogenic Detrusor Overactivity, Overactive Bladder, Pharmacokinetics of Mirabegron
- Trial name
- NCT02211846
- Testing
- Mirabegron
- Where
- 13 sites in Belgium, Denmark and 3 more
- Volunteers
- 34 people
- Sponsor
- Astellas Pharma Inc
Acne Vulgaris
Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel
This will be an open-label study designed to assess the safety and plasma PK of topically applied IDP-126 Gel compared to Control Gel.
- Trial name
- NCT03653403
- Testing
- IDP-126 Gel, Control Gel
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Bausch Health Americas, Inc.
Iron Deficiency
Absorption of Heme and Non-Heme Iron in Pregnant and Non-pregnant Women and Mechanisms of Fetal Iron Transfer
The three specific aims of this study are 1) to assess the impact of iron status on relative differences in absorption of heme and non-heme iron among pregnant women and non-pregnant women, 2) to assess the magnitude and the…
- Trial name
- NCT01019096
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cornell University
Osteoporosis
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents
The primary aim of this proposal is to determine the effects of soluble corn fiber (SCF) supplementation for 1 year on bone metabolism in growing adolescents compared to controls.
- Trial name
- MetA-Bone (NCT02916862)
- Testing
- Soluble Corn Fiber (SCF) without Calcium, Soluble Corn Fiber (SCF) + Calcium
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Florida International University