Clinical trials: Acceptability
Severe Acute Malnutrition
Efficacy and Acceptability of RUTFs in Indonesia
Severe wasting or Severe Acute Malnutrition (SAM) continues to be a major public health problem in Indonesia, affecting more than 2 million children under 5 years old.
- Trial name
- NCT05614505
- Testing
- Ready to use therapeutic foods
- Where
- Indonesia
- Volunteers
- 300 people
- Sponsor
- Institut de Recherche pour le Developpement
Maternal Care Patterns
Effectiveness and Acceptability of Availing Skilled Birth Attendance (SBA) Services Through Community Reproductive Health Nurses (CORN) to a Household Level at Rural Communities of Ethiopia; A Cluster Community Trial in Gedeo Zone, SNNPR
Rationale: Every year, 287,00 million women, and 3.1 million neonates continue to die, and the majority of these deaths have been identified as being avoidable.
- Trial name
- CORN (NCT02501252)
- Testing
- trained midwives and nurses working in the community to provide skilled SBA services
- Where
- Ethiopia
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Dilla University
Cerebral Palsy
Feasibility of a Robot-Guided Active Play Intervention for Children With Cerebral Palsy
Cerebral palsy can make it difficult for children and adolescents to participate consistently in enjoyable physical activity. This study will examine whether a small humanoid robot called NAO can deliver a short, story-based…
- Trial name
- REACT (NCT07842328)
- Testing
- Humanoid Robot-Guided Active Play Intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Diarrhea
Tolerability and Acceptability of Fibersol-2 in Children
Dietary fiber, a non-digestible carbohydrate, used in decades for the beneficial effect on health with physiological importance because such compounds have low energy values.
- Trial name
- NCT03565393
- Testing
- Fibersol-2
- Where
- Bangladesh
- Volunteers
- 92 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Substance Use Disorders, Criminal Behavior
Feasibility, Acceptability and Preliminary Treatment Effects of A-CRA for Youth in Compulsory Institutional Care
Substance abuse and criminal behavior are increasing among adolescents in Sweden. The Swedish National Board of Institutional Care, SiS, provides institutional care on basis of the Swedish laws Care of Young Persons (Special…
- Trial name
- NCT05081934
- Testing
- A-CRA, TAU
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy
Motor Training for Infants With Cerebral Palsy
The intervention in this study, Let's Move, is a motor intervention for infants at risk for cerebral palsy. We will test the feasibility and acceptability of the intervention as well as preliminary effectiveness.
- Trial name
- NCT04886895
- Testing
- Let's Move Motor Intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
HIV
A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods
This study will enrol sexually active, healthy girls aged 16-17 to assess and compare the acceptability and preference for a monthly vaginal ring, bi-monthly injectable contraception or daily dose oral contraception, as proxy for…
- Trial name
- UChoose (NCT02404038)
- Testing
- Nur-Isterate, Nuvaring, Triphasil
- Where
- South Africa
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Centre
Life Style, Health-Related Behavior
A Group Intervention for Promoting Health-related Habits (LEV-G)
Health-related habits influences mental and physical health. Still, treatment of health-related habits, which can help to remedy health problems, is often not done at all or very superficially.
- Conditions
- Life Style, Health-Related Behavior, Disabilities Mental, Disability Physical
- Trial name
- NCT06404632
- Testing
- Lev-g
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Nutrition Disorders
Acceptability and Tolerance Study of a Plant-based Tube Feed
This is a single arm, prospective, multi-centre study to evaluate the gastrointestinal tolerance and compliance over a 7-day period with a plant based tube feed.
- Trial name
- NCT06209593
- Testing
- Compleat plant protein tube feed
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Société des Produits Nestlé (SPN)
Acceptability of Health Care, Adherence, Medication
Project Engage: Oral PrEP Acceptability
This study is a two-arm open label acceptability study that will examine acceptability of, and adherence to, once daily dosing regimen of F/TDF (Truvada) and an investigational once daily dosing regimen of F/TAF (Descovy) under…
- Trial name
- NCT05458765
- Testing
- emtricitabine/tenofovir alafenamide, Emtricitabine / Tenofovir Disoproxil Oral Tablet
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Omphalitis, Septicaemia
Efficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newborn Infections in Uganda: a Randomized Controlled Trial
Background: Nearly all the yearly 3.3 million neonatal deaths occur in low and middle income countries. Infections, including those affecting the umbilical cord (omphalitis) are a significant factor in approximately a third of…
- Trial name
- NCT02606565
- Testing
- Intervention arm: 4% chlorhexidine
- Where
- Uganda
- Volunteers
- 4,760 people, healthy volunteers welcome
- Sponsor
- Makerere University
Malaria,Falciparum
The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children
Across sub-Saharan Africa, school-age children bear an under-appreciated burden of malaria. An estimated 200 million school-age children are at risk of malaria and in many areas prevalence of infection exceeds 50%.
- Trial name
- NCT06424002
- Testing
- Mosquirixs, artemether-lumefantrine
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- Kamuzu University of Health Sciences
Child, Preschool
How Young is Too Young for Virtual Reality? Determining Usability and Acceptability in Ages 2-6 in the Emergency Department
Children who present to the emergency department often require painful procedures (intravenous catheterization, laceration repair, fracture reduction, etc.).
- Trial name
- NCT03692377
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Complete Abortion
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days' Gestation in Kazakhstan
The study will be conducted in 4 sites and will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in…
- Trial name
- NCT02018796
- Testing
- Mifepristone, misoprostol
- Where
- 4 sites in Kazakhstan
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Dietary Exposure
Acceptability and Tolerance Study of Adult Tube Feed with Food with Food Derived Ingredients.
Product acceptability data from 15 participants are required in order to submit an application to the Advisory Committee on Borderline Substances (ACBS) and the Health Service Executive (HSE) submission for Ireland for product…
- Trial name
- NCT06102122
- Testing
- Compleat
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Société des Produits Nestlé (SPN)
Periodontitis, Premature Birth of Newborn
Feasibility and Acceptability of Use of Daily Oral Rinse in Pregnant Women in Rural Nepal
In Nepal, investigators are conducting a cohort study to estimate the relationship between signs of periodontal disease in pregnant women and preterm delivery.
- Trial name
- NCT02788786
- Testing
- Chlorhexidine, Cetylpyridinium chloride, Salt and Water
- Where
- Nepal
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Tyrosinemia, AKU
Evaluation of TYR Sphere in France
10 participants aged 3 years and over with tyrosinaemia or alkaptonuria will be prescribed Tyr sphere following an assessment of their individual needs by their dietitian.
- Trial name
- TYR sphere Fra (NCT04761588)
- Testing
- Tyr sphere
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Vitaflo International, Ltd
Opisthorchis Viverrini
Efficacy and Safety of Ascending Doses of Arpraziquantel in Children Infected With Opisthorchis Viverrini
This study aims to assess the efficacy, safety and acceptability of ascending doses of arpraziquantel in children infected with Opisthorchis viverrini.
- Trial name
- ADORA-VI (NCT07262814)
- Testing
- Apraziquantel
- Where
- Laos
- Volunteers
- 125 people
- Sponsor
- Jennifer Keiser
Moderate Acute Malnutrition
Treating Moderate Malnutrition in 6-24 Months Old Children
Child malnutrition is intimately associated to poverty and may be due to sub-optimal feeding behaviours, food insecurity at household level, or a combination of both.
- Trial name
- LUCOMA (NCT01115647)
- Testing
- Ready-to-Use Therapeutic Food (RUTF), CBS++, CCC
- Where
- Burkina Faso
- Volunteers
- 2,088 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Sickle Cell Disease
Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
Chronic Pain is associated with morbidity and poor quality of life in patients with Sickle Cell Disease (SCD). Complementary therapies, such as yoga are beneficial in patients with non-SCD chronic pain conditions.
- Trial name
- NCT03694548
- Testing
- Part A Survey, Part B Yoga Program
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University