Clinical trials: Access and Evaluation
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1
This project builds on the Michigan Contraceptive Access Research and Evaluation Study (M-CARES) to evaluate the long-term effects of mothers' access to free contraceptives and reductions in unintended pregnancies on their…
- Trial name
- M-CARES-K (NCT04371900)
- Testing
- Mother receives voucher valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023), Mother receives voucher valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019)
- Where
- 9 sites in United States
- Volunteers
- 4,700 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression
Promoting Treatment Access Following Pediatric Primary Care Depression Screening
Major depression (MD) in youth is a serious psychiatric illness with extensive morbidity and mortality. The American Academy of Pediatrics recently released practice guidelines promoting primary care (PC)-based youth MD…
- Trial name
- NCT04030897
- Testing
- Parent-Directed Online Single-Session Program, Youth-Directed Online Single-Session Program, Information/Psychoeducation/Referral
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- Stony Brook University
HAV
Access Anti-HAV and Access Anti-HAV IgM Assays EU Clinical Trial Protocol (HAV-EU-11-23)
The purpose of this study is to evaluate the clinical performance supporting that intended purpose of the Access anti-HAV as an aid in the laboratory diagnosis of HAV infection and for detection of anti-HAV after vaccination and…
- Trial name
- NCT06289868
- Testing
- Access anti-HAV and Access anti-HAV IgM on the DxI 9000 Access Immunoassay Analyzer and CE-marked predicate assays, Access anti-HAV on the DxI 9000 Access Immunoassay Analyzer and CE-marked predicate assays
- Where
- 2 sites in France
- Volunteers
- 1,409 people
- Sponsor
- Beckman Coulter, Inc.
Virtual Reality, Children and Adolescents
Evaluation of the Efficacy of a Virtual Reality When Placing a Needle on an Implantable Venous Access Device in Children With Leukemia
Main objective: Evaluate the effectiveness of the repeated use of interactive or hypnotic virtual reality compared to standard treatment, on pain, during each needle placement on PAC for 3 months on children or adolescents (6 to…
- Conditions
- Virtual Reality, Children and Adolescents, Acute Leukemia, Anxiety and Fear
- Trial name
- LEAVE (NCT06697275)
- Testing
- Hypnotic Virtual reality, Interactive virtual reality, Standard method
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Melanoma
PAN-EU Utilization, Effectiveness and Safety of Ipilimumab Administered in EAP Patients With Advanced Melanoma
Observational study to evaluate the effectiveness and safety of ipilimumab, administered during the European expanded access programme (EAP) in pretreated patients with advanced (unresectable or metastatic) melanoma.
- Trial name
- NCT02492815
- Where
- 17 sites in United States, Austria and 14 more
- Volunteers
- 1,773 people
- Sponsor
- Bristol-Myers Squibb
Brain Injury, Craniocerebral Trauma
PariS-TBI Study : Paris Severe Traumatic Brain Injury Study
The primary objective of the protocol is to study the long-term outcome of a large group of traumatic brain injury patients. This outcome is to be described in terms of activity, participation, quality of life, SOCIO-professional…
- Conditions
- Brain Injury, Craniocerebral Trauma, Trauma Nervous System
- Trial name
- PariS-TBI (NCT01437683)
- Where
- France
- Volunteers
- 252 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Injury
Intermediate Size Patient Population Expanded Access Protocol to Evaluate HB-adMSCs for the Treatment of Patients With Traumatic or Nontraumatic Brain Injury
This expanded access protocol is part of IND 031942 to evaluate efficacy and safety of multiple intravenous administrations of allogeneic HB-adMSCs for the treatment of nontraumatic or traumatic brain injury for up to 8 patients…
- Trial name
- NCT07164482
- Testing
- HB- adMSCs (Hope Biosciences adipose derived mesenchymal stem cells)
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Sickle Cell Disease
Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines
The overall goal of this proposed project is to 1) increase co-management between sickle cell specialists and primary care providers (PCP's); 2) increase the use of hydroxyurea (HU) which prevents Vaso-Occlusive Episode (VOE)…
- Trial name
- NCT03037021
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Duke University
Venepuncture
Evaluation of a Touchless Vein Scanner for Venepuncture and Cannulation in Pediatric Patients
Evaluation of the AccuVein ® AV 300 vein scanner in clinical routine in a pediatric operation room setting for a 4 weeks period.
- Trial name
- VENSCAN (NCT01434537)
- Where
- Germany
- Volunteers
- 238 people
- Sponsor
- Charite University, Berlin, Germany
Sanfilippo Syndrome Type A
Phase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA)
The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of recombinant human heparan N-sulfatase (rhHNS, GC1130A) administered via intracerebroventricular access device…
- Trial name
- NCT06567769
- Testing
- GC1130A
- Where
- 4 sites in United States, South Korea
- Volunteers
- 9 people
- Sponsor
- GC Biopharma Corp
Mother-to-child Transmission of HIV, Pregnancy
Trial to Improve Access to PMTCT Services and Reduce HIV Transmission From Mother to Child
The purpose of this study is to determine the effectiveness, cost-effectiveness, feasibility and acceptability of an enhanced community health worker (CHW) intervention and outreach system to improve antenatal care and PMTCT…
- Trial name
- FS (NCT01932138)
- Testing
- Enhanced CHW intervention, Standard of care
- Where
- Tanzania
- Volunteers
- 190,530 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Prostate Cancer
Study to Gather Information About the Use of Healthcare Services and the Way the Disease is Cared for in Canadian Patients With Prostate Gland Cancer Which Spread Throughout the Body
Study to gather information about the optimal placement of Ra-223 in the order of different treatments in terms of the effect on patients and in terms of the use of healthcare services for the treatment of Canadian patients with…
- Trial name
- REACTIVATE (NCT04281147)
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223)
- Where
- Canada
- Volunteers
- 4,301 people
- Sponsor
- Bayer
Congenital Heart Disease
TORCH-LATAM: A Regional Pathway to Improve Transplant Evaluation for Congenital Heart Disease
Congenital heart disease can progress to advanced cardiac or cardiopulmonary failure requiring heart, heart-lung, or, in selected congenital conditions, bilateral lung transplantation with cardiac repair.
- Trial name
- TORCH-LATAM (NCT07799272)
- Testing
- TORCH Integrated Transplant Access Pathway (TORCH-ITAP)
- Volunteers
- 600 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
HIV Infections
Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations
The purpose of this study is to see if it is safe and effective to give adefovir plus other anti-HIV drugs to HIV-infected patients who have failed other anti-HIV drug combinations.
- Trial name
- NCT00002398
- Testing
- Levocarnitine, Adefovir dipivoxil
- Where
- United States
- Sponsor
- Gilead Sciences
Health Care Quality, Access, and Evaluation, Smoking Cessation
PROS Smokebusters: Adolescent Smoking Cessation in Pediatric Primary Care
This is a pilot study addressing office systems and clinician behavior change surrounding smoking cessation interventions for teens.
- Trial name
- NCT00135265
- Testing
- smoking cessation, practice change
- Where
- United States
- Volunteers
- 4,100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Skill Development of Staff, Clinical Practice
Peripheral Venous Access Management by Radiologic Technologists in Radiodiagnostic Procedure
The goal of this interventional study is to evaluate the impact of a structured training program on the ability of Radiologic Technologists (RTs) to safely and effectively perform peripheral venous access (PVA) placement for…
- Conditions
- Skill Development of Staff, Clinical Practice, Patient Satisfaction
- Trial name
- TSRM_01 (NCT07411430)
- Testing
- Structured Peripheral Venous Access Training Program
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Chronic Headache
Direct Access to MRI and Neurology Referrals for the Management of Patients With Chronic Headache.
This study aims to evaluate whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache decreases overall NHS costs and increases patient satisfaction compared to…
- Trial name
- NCT02753933
- Testing
- MRI scan, Neurology Appointment
- Where
- United Kingdom
- Volunteers
- 296 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pediatric Cancer
Reducing Port Access Pain and Clinic Wait Time: An Evaluation of EMLA Cream Versus nüm™ Vapocoolant Spray
The goal of this clinical trial is to compare a sterile vapocoolant spray to EMLA cream in children with access ports. Participants will receive either the spray or cream prior to port access and rate pain on a scale.
- Trial name
- NCT06023368
- Testing
- Num Vapocoolant Spray, EMLA Cream
- Where
- United States
- Sponsor
- Marianne Hutti
Anxiety Disorder, Obsessive-Compulsive Disorder
BIP in Jämtland Härjedalen: Increased Access to CBT Within Regular Health Care in Northern Sweden
The purpose of this study is to test internet-delivered cognitive behavior therapy for children and adolescents with anxiety disorders and obsessive-compulsive disorder in a routine clinical setting in a rural part of Sweden.
- Trial name
- BIPBJÖRN (NCT02926365)
- Testing
- ICBT
- Where
- Sweden
- Volunteers
- 83 people
- Sponsor
- Karolinska Institutet