Clinical trials: Acute Bronchiolitis
Acute Viral Bronchiolitis
Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis
The purpose of this study is to determine whether nebulized hypertonic saline solution reduces the admission rate 48 hours after initial treatment in the emergency department, when compared to normal saline solution (control).
- Trial name
- GUERANDE (NCT01777347)
- Testing
- 3% Saline, 0.9% Normal Saline
- Where
- 21 sites in France
- Volunteers
- 778 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bronchiolitis Acute
Bronchiolitis Clearance Airways With Seaserum
The objective of this study is to show that the use of electrodialyzed seawater reduces the duration (in days) of symptoms in acute infant bronchiolitis compared with the use of saline solution in infants aged 1 month to less…
- Trial name
- B-CLASS (NCT06177197)
- Testing
- Physiomer, Saline solution
- Where
- 8 sites in France
- Volunteers
- 458 people
- Sponsor
- University Hospital, Brest
Bronchiolitis, Viral
Efficacy and Safety of Curosurf® in Patients Invasively Ventilated for Severe Bronchiolitis Under 12 Months of Age
Background. Viral bronchiolitis is a common cause of hospitalization for acute respiratory insufficiency in young infants. Despite several RCT have tested the effectiveness of various agents, currently there is no proven specific…
- Trial name
- NCT03959384
- Testing
- Curosurf 80Mg/Ml Intratracheal Suspension, Ambient Air
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Bronchiolitis
Vitamin D Supplementation for Acute Bronchiolitis
This study was conducted to evaluate the effect of oral vitamin D supplementation on the clinical course of acute bronchiolitis, and to investigate whether vitamin D deficiency among infants who required hospital-based care for…
- Trial name
- NCT03799406
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Acute Disease Respiratory
Use Of The ABSS In Infants With ARIS Treated With Outpatient Respiratory Physiotherapy
Background. Acute respiratory infections in childhood have high incidence and morbimortality rates, generating significant sanitary and social costs.
- Trial name
- NCT04036591
- Testing
- Acute Bronchiolitis Severity Scale (ABSS)
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- FisioRespiración
Respiratory Infections, Bronchiolitis
An Epidemiological Study to Evaluate the RSV-Associated Lower Respiratory Track in Infections in Infants
The primary objective of this study is to describe the incidence of RSV-associated LRI among infants <1 year of age presenting to the ED during selected shoulder months.
- Conditions
- Respiratory Infections, Bronchiolitis, Pneumonia, Apnea
- Trial name
- NCT00369759
- Testing
- Emergency Dept. Subjects with LRI or Apnea
- Where
- 38 sites in United States
- Volunteers
- 2,048 people
- Sponsor
- MedImmune LLC
Acute Bronchiolitis
Nebulised 3% Hypertonic Saline in Infants With Acute Bronchiolitis
This study aims to determine the efficacy of nebulising 3% hypertonic saline in improving clinical symptoms and reducing the length of hospital stay in infants with acute bronchiolitis.
- Trial name
- NCT06558461
- Testing
- 3% Sodium Chloride, Standard care
- Where
- Vietnam
- Volunteers
- 140 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Bronchiolitis, Bronchiolitis Acute
Descriptive Study of the Initial Management of Young Children With Moderate Acute BRONCHiotitis With Home Hospitalisation
The occurrence of a first episode of acute bronchiolitis in an infant or young child (3 months-2 years) always represents a medical event that generates stress for parents and in some cases for the primary care physician when it…
- Trial name
- BRONCHAD (NCT06842238)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Elsan
Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections
Assessing the Burden of Respiratory Syncytial Virus (RSV)
This study examines the impact of Respiratory Syncytial Virus (RSV) on people of all ages, from infants to the elderly. It uses hospital records collected between January 2018 and December 2024 to understand: How often does RSV…
- Conditions
- Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections, Bronchiolitis, Pneumonia
- Trial name
- NCT07015255
- Where
- United Arab Emirates
- Volunteers
- 1,500 people
- Sponsor
- Abu Dhabi Health Services Company
Bronchiolitis
Single Dose Versus Multiple Doses of Dexamethasone in Children With Acute Bronchiolitis
This study is to determine the effectiveness of five-day treatment versus a single dose of oral dexamethasone (corticosteroid) in children between 2 and 24 months of age with a first episode of acute bronchiolitis presenting in…
- Trial name
- NCT00213226
- Testing
- dexamethasone
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- The Hospital for Sick Children
Bronchiolitis, Viral, Saline Solution, Hypertonic
Hypertonic Saline for Acute Bronchiolitis
The purpose of this study is to determine whether nebulized 3% hypertonic saline (HS) improves respiratory distress in children 2-23 months presenting to the emergency department (ED) with acute bronchiolitis with persistent…
- Trial name
- NCT01247064
- Testing
- Nebulized 3% saline, Nebulized 0.9% Normal Saline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Hospital of Philadelphia
Acute Hepatitis C
Australian Trial in Acute Hepatitis C Recall Study
A single long-term follow up assessment of an established multi-centre, prospective longitudinal cohort study of patients for clinical, psychosocial, immunovirological outcomes 4 to 8 years after previous treatment for recently…
- Trial name
- ATAHC Recall (NCT02000063)
- Where
- 3 sites in Australia
- Volunteers
- 50 people
- Sponsor
- Kirby Institute
Bronchiolitis, Respiratory Disease
Isotonic Saline for Children With Bronchiolitis
The goal of this randomized clinical trial is to investigate the optimal supportive treatment of bronchiolitis in infants from 0-12 months of age.
- Conditions
- Bronchiolitis, Respiratory Disease, Asthma in Children, Viral Infection
- Trial name
- NCT05902702
- Testing
- Nebulized isotonic saline, Nasal irrigation with isotonic saline
- Volunteers
- 300 people
- Sponsor
- Slagelse Hospital
Bronchiolitis Acute
Nebulized N-Acetyl Cysteine for Bronchiolitis in Inpatient Hospital Use
Bronchiolitis is the major cause of hospital admission in infants < 6 months of age and usually viruses like Respiratory syncytial virus (RSV), human metapneumo virus, Adeno virus, para-influenza virus, Rhino virus and influenza…
- Trial name
- NCT03364218
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Carilion Clinic
Acute Bronchiolitis
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department
This is a prospective, randomized, controlled, double-blinded, clinical trial Subject : 3mo ~ 24mo. aged infants with bronchiolitis The effect of 3 % NaCl nebulizer or dexamethasone on admission rate of these infants in ED.
- Trial name
- NCT01660867
- Testing
- 0.9% saline + oral dexamethasone
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Wounds and Injuries, Burns
Treatment of Wounds With a New Adhesive Foam Dressing
This study will look at whether ELECT, a new adhesive foam dressing, can offer an alternative to traditional wound care methods. Patients will be treated with ELECT for 14 days.
- Trial name
- NCT02807584
- Testing
- ELECT
- Where
- South Africa
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Bronchiolitis, Pneumonia
National Observatory of Children Hospitalized for Acute Respiratory Distress or Lower Respiratory Tract Infections
This study is an observational, multicenter and prospective study for surveillance of case of hospitalised children acute respiratory distress or lower respiratory tract infections
- Conditions
- Bronchiolitis, Pneumonia, Asthma
- Trial name
- OVNI (NCT06112132)
- Where
- France
- Volunteers
- 1,827 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Acute Bronchiolitis
Nebulized 3% Hypertonic Saline Versus Normal Saline in Managing Children With Acute Bronchiolitis: A Randomized Controlled Trial
This randomized controlled trial was conducted at A-Ramadi Teaching Hospital for Maternity and Children on patients admitted with acute bronchiolitis. The study covered a duration of 6 months.
- Trial name
- NCT07138625
- Testing
- Nebulized normal saline
- Volunteers
- 300 people
- Sponsor
- University Of Anbar
Bronchiolitis Acute Viral
Eliminating Monitor Overuse Trial (EMO Trial)
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
- Trial name
- NCT05132322
- Testing
- Educational Outreach, Audit & Feedback (unit level), Audit & Feedback (real time, individual-level)
- Where
- 51 sites in United States, Canada
- Volunteers
- 9,265 people
- Sponsor
- Children's Hospital of Philadelphia
Graft Vs Host Disease
Ruxolitinib for Steroid-refractory GVHD
Steroid-refractory acute GVHD (srGVHD) is one of the causes of mortality after allogeneic stem cell transplantation, while steroid-refractory chronic GVHD significantly increases morbidity, aggravates quality of life and may also…
- Trial name
- NCT02997280
- Testing
- Ruxolitinib Oral Tablet
- Where
- Russia
- Volunteers
- 75 people
- Sponsor
- St. Petersburg State Pavlov Medical University