Clinical trials: Adaptation
Autism Spectrum Disorder, Developmental Language Disorder
Efficacy of a Pragmatic Intervention to Improve Adaptation to Context and Interlocutor
Patients with Developmental Language Disorder (DLD) or Autism Spectrum Disorder (ASD) have communicational difficulties to adapt their language to context and to interlocutors.
- Trial name
- NCT05127863
- Testing
- social communication intervention (pragmatic)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Université Catholique de Louvain
Child Behavior
Effect of Sensory Adapted Dental Environment on Children's Behavior During Dental Treatment
The objective of the present study is to determine the effect of sensory adapted dental environment (SADE) in healthy children during a routine dental restorative treatment.
- Trial name
- NCT03366467
- Testing
- SADE, RDE
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
CHD - Congenital Heart Disease
Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program
Standard cardiovascular rehabilitation is performed in a medical care and rehabilitation centre. However, it may not be adapted to the patient's profile and there are few medical care and rehabilitation centres specialized in…
- Trial name
- Muscletoncoeur (NCT07115589)
- Testing
- Muscle Your Heart home-based program
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Food Hypersensitivity, Allergy
Validation of Turkish Versions Child- and Parent-Rated Scales of Food Allergy Anxiety
This study aims to evaluate the psychometric properties of the Turkish adaptation of the Scale of Food Allergy Anxiety (SOFAA), including both the child-report and parent-report versions.
- Conditions
- Food Hypersensitivity, Allergy, Phobic Disorders, Caregiver Burden
- Trial name
- NCT07019389
- Testing
- Turkish Version of the Scale of Food Allergy Anxiety (SOFAA)
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Depression, Adolescent Depression
"Culturally Adapted CBT for Depression in Arab and Asian Adolescents in the UAE (CA-CBT)"
This study evaluated the effectiveness of a culturally adapted form of Cognitive Behavioural Therapy (CA-CBT) for reducing depression among Arab and Asian adolescents in the United Arab Emirates (UAE).
- Conditions
- Depression, Adolescent Depression, Mental Health, Psychological Stress
- Trial name
- CA-CBT (NCT07109973)
- Testing
- Culturally Adapted Cognitive Behavioural Therapy (CA-CBT), Treatment-as-Usual (TAU)
- Where
- United Arab Emirates
- Volunteers
- 175 people
- Sponsor
- Bath Spa University Academic Centre RAK
Autism Spectrum Disorder, Mental Health Disorder
Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services
The purpose of this project is to conduct a feasibility test of an ASD executive functioning intervention adapted for mental health settings, including examining the effectiveness and process of implementing this adapted…
- Conditions
- Autism Spectrum Disorder, Mental Health Disorder, Executive Dysfunction
- Trial name
- NCT04295512
- Testing
- Unstuck and on Target
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- San Diego State University
Hodgkin Disease
A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
The purpose of this study is to determine whether nivolumab plus brentuximab vedotin (followed by brentuximab vedotin plus bendamustine in patient with suboptimal response) is safe and effective in treating patients with…
- Trial name
- CheckMate 744 (NCT02927769)
- Testing
- Nivolumab, brentuximab vedotin, bendamustine
- Where
- 79 sites in United States, Canada and 9 more
- Volunteers
- 72 people
- Sponsor
- Bristol-Myers Squibb
Pediatric Cancer
Cross-cultural Adaptation and Validation of the P-CIN for Chinese Pediatric Oncology Patients
The goal of this study was to conduct a cross-cultural adaptation of the P-CIN into the Chinese context, assess its psychometric properties, and determine the cut-off value of CIPN among Chinese pediatric oncology patients.
- Trial name
- NCT07053579
- Where
- 2 sites in Hong Kong
- Volunteers
- 313 people
- Sponsor
- The Hong Kong Polytechnic University
Medulloblastoma
Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma
Medulloblastoma is a rare brain malignancy, mainly affecting children. Treatment of this rapidly growing tumor begins with maximal surgical removal plus radiation and chemotherapy. Treatment toxicity is high.
- Trial name
- PersoMed-I (NCT04402073)
- Testing
- Sonidegib, Cisplatin, Lomustine
- Where
- 50 sites in Australia, Austria and 6 more
- Volunteers
- 20 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
ADHD, PTSD
Trauma-adapted Yoga in Child & Adolescent Psychiatry.
The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the…
- Conditions
- ADHD, PTSD, Quality of Life, Self-Control
- Trial name
- TAY-CAP (NCT06330779)
- Testing
- Trauma-adapted yoga
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University West, Sweden
Evaluation of Marginal and Internal Fit of Metal Crowns
Comparison of Marginal Fit and Internal Adaptation in All-Metal Crowns: an in Vitro Experimental Trial
The goal of this in vitro study is to compare the marginal fit and internal adaptation of all-metal crowns in polished crown preparations and non-polished crown preparations The main question it aims to answer is: are the non…
- Trial name
- NCT06067945
- Testing
- microleakage
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Autism Spectrum Disorder
Culturally Adapted Play-Based Behavioural Intervention for Autism
This study compared Culturally Adapted Play-Based Behavioural Intervention (PPBI) and Applied Behaviour Analysis (ABA) for children with Autism Spectrum Disorder (ASD) in semi-rural Tamil Nadu through a double-blinded randomized…
- Trial name
- NCT06859541
- Testing
- Culturally Adapted Play-Based Behavioural Intervention, Applied Behaviour Analysis
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Saveetha University
Myopia
Comparing Myopia Control Spectacle Lenses for Visual Comfort, Adaptation, and Satisfaction in Myopic Children
The goal of this clinical trial is to demonstrate that the visual comfort, adaptation, and overall satisfaction associated with the use of the test spectacle lenses are not inferior to those of the control spectacle lenses in…
- Trial name
- EVASION (NCT07683481)
- Testing
- HADAL Spectacle Lenses, Stellest® Spectacle Lenses
- Volunteers
- 20 people
- Sponsor
- Essilor International
Mental Disorder, HIV Stigma
Project Yes+ for Young MSM Living With HIV in Vietnam
In Vietnam, adolescent and young men who have sex with men (AYMSM) are among those most affected by HIV, and they also experience significant HIV-related mental health and stigma challenges.
- Trial name
- To-Hieu (NCT07514221)
- Testing
- To-Hieu (I understand)
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Hanoi Medical University
HRV, Psychological Adaptation
Weight Cut Stress: the Hidden Struggle Beyond Fight Day
This study investigated the effects of rapid weight-cutting on stress in elite kickboxers by analyzing Heart Rate Variability (HRV) and subjective stress levels using a Visual Analog Scale (VAS).
- Trial name
- NCT06860204
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Acute Myeloid Leukemia
MRD Response-adapted Allo-HSCT for Adverse-risk AML
This TROPHY-AML01 regimen aims to identify the effectiveness and safety of MRD response-adapted allo-HSCT for adverse-risk acute myeloid leukemia in an open-label, randomized, controlled trial.
- Trial name
- NCT06301425
- Testing
- Intervention group, Control group
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Peking University People's Hospital
Juvenile Idiopathic Arthritis
Interest of an Adapted Physical Activity (APA) Program Among Patients With Juvenile Idiopathic Arthritis: a Feasibility and Efficacy Preliminary Study
The Juvenile Idiopathic Arthritis (JIA) affects joints mobility and leads pain, impacting the practice of physical activities. Adapted Physical Activities are rehabilitation methods increasingly used, but additional studies are…
- Trial name
- ATHLETIQUE (NCT05572424)
- Testing
- Adaptated Physical Activity (APA) + pedometer watch
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Child Development
Arabic Ages and Stages Questionnaire-III
Early detection and intervention for developmental delays are crucial in promoting healthy child development, hence the need for formal screening.
- Trial name
- NCT02539251
- Testing
- Arabic ASQ -3
- Where
- Lebanon
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Type 1 Diabetes
Adaptation of REDCHIP Intervention for the Portuguese Context
The present Feasibility Randomized Controlled Trial (FRCT) aims to assess the acceptability and effectiveness of REDCHiP intervention, targeting parents of young children with T1D, followed in two major Portuguese hospitals.
- Trial name
- REDCHIP (NCT07201779)
- Testing
- REDCHiP, Treatment As Usual Control Group
- Volunteers
- 44 people
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary