Clinical trials: Adaptive Behavior
Suicidal and Self-injurious Behavior, Linkage to Care
An Adaptive Intervention to Increase Engagement to Community-Based Care After an ED Admission
The goal of this study is to develop a feasible brief, family-based adaptive intervention, via SMART design, for youth with suicidal and non-suicidal self-injurious behavior (SSIB) to increase community-based mental health (MH)…
- Trial name
- ED_SMART (NCT07092345)
- Testing
- adaptive intervention
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Rhode Island Hospital
Behavior, Adaptive, Behavior, Child
Discover Learning - Social, Emotional and Identity Learning for Very Young Adolescents
The primary aim of the Discover Learning Project (Discover) is to test an intervention for Very Young Adolescents (VYAs) to promote positive, gender norm transformative, social emotional and identity learning (SEIL).
- Conditions
- Behavior, Adaptive, Behavior, Child, Behavior, Social
- Trial name
- NCT04458077
- Testing
- Discover Learning (SEIL)
- Where
- 4 sites in Tanzania
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Autism Spectrum Disorder
The Listening Program® With Bone Conduction Headphones Changes Hypersensitivity to Sound and Behavioral Responses
There are limited approaches to specifically address auditory sensory over- and under-responsivity (SOR) in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT05009095
- Testing
- The Listening Program® with bone conduction headphones
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Health
Conduct Problems
Adaptive Intervention Strategies in Conduct Problems Prevention
This pilot study conducts feasibility research to develop adaptive intervention strategies for conduct problems prevention. The adaptive model will stipulate for whom only brief prevention strategies are sufficient and for whom…
- Trial name
- NCT02414074
- Testing
- Youth Behavioral Intervention, Parent Education
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Minnesota
Transplant, Adaptive Immunity
CNTRP POSITIVE Study
Adequate control of immunosuppression is critical in preventing graft failure after solid organ transplantation (SOT) and in avoiding life-threatening viral and malignant complications.
- Conditions
- Transplant, Adaptive Immunity, EBV, Medication Adherence
- Trial name
- NCT02318030
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder (ASD
RCT of SCERTS (Social Communication, Emotional Regulation, Transactional Support) Program for Children With Autism Spectrum Disorder
This randomized control trial aims to assess the efficacy of the SCERTS intervention in children aged 3-6 years diagnosed with mild to moderate Autism Spectrum Disorder (ASD).
- Trial name
- NCT06733324
- Testing
- SCERTS (Social Communication, Emotional Regulation, Transactional Support), Behavioral Treatment, Speech Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Aisha Saleem
Substance Use Disorders, Risk Behavior
Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial
This Stage II randomized trial tests Culturally Informed \& Flexible Family Based Treatment for Adolescents (CIFFTA) developed as part of a Stage I treatment development effort and yielding promising preliminary findings.
- Conditions
- Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
- Trial name
- CIFFTA (NCT01823250)
- Testing
- Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Miami
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD
Evaluation of a Novel Quantum-Inspired Intervention (QII) for Children With Autism Spectrum Disorder: A Global Confirmatory Study
The purpose of this global multicenter confirmatory study is to evaluate the clinical efficacy and safety of Quantum-Inspired Intervention (QII), a novel non-invasive neurodevelopmental protocol, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, ASD
- Trial name
- NCT07898787
- Testing
- Quantum-Inspired Intervention (QII)
- Volunteers
- 80 people
- Sponsor
- BlissBot, Inc
Behavior, Adaptive
The Prenatal/Early Infancy Project: An Adolescent Follow-up
The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977.
- Trial name
- NCT03079752
- Testing
- Developmental Screening, Screening plus Transportation, Screening, Transport, Prenatal Visits
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Attention Deficit Disorder With Hyperactivity
Adaptive Response to Intervention (RTI) for Students With ADHD
Purpose: The primary purpose of the proposed project is to investigate the efficacy of Tier 1 and Tier 2 interventions delivered through a Response to Intervention (RTI) framework for children with attention-deficit/hyperactivity…
- Trial name
- NCT03511976
- Testing
- Tier 1 Classroom Management, Daily Report Card (DRC), Enhanced DRC (DRC-E)
- Where
- 2 sites in United States
- Sponsor
- Florida International University
Substance Use
Developing a Digital Intervention to Prevent Risky Health Behaviors
The project will launch the development of Parents and Teens Together (PATT), a dyadic digital parent-teen prevention intervention, for families of young teens experimenting or at high risk for experimenting with substance use…
- Trial name
- PATT (NCT06538922)
- Testing
- Single Session Family Intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Genetic Syndrome
I-TOPS With Patients With Genetic Syndrome SYN-TOPS
Genetic syndromes involving the central nervous system are often associated with cognitive, behavioral and communication difficulties that negatively impact adaptive functioning and quality of life.
- Trial name
- SYN-TOPS (NCT07563218)
- Testing
- Italian Tailored Online Problem-Solving (I-TOPS)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Eugenio Medea
Neurodevelopmental Disorders With Severe Self-injuries
Efficacy of Cannabidiol in the Management of Self-injuries in Children and Adolescents With Severe Neurodevelopmental Disorders.
Self-injuries includes repetitive actions directed at oneself, such as biting, hitting, hitting one's head or limbs, slapping oneself, pulling one's hair, or hitting oneself in the eyes, which can lead to severe injury.
- Trial name
- CBD-SIB (NCT07564245)
- Testing
- Cannabidiol
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health and Well-being, Family Functioning
A Just-in-Time Adaptive Intervention for Child and Family Mental Health
The goal of this clinical trial is to test an app-based just-in-time-adaptive intervention (JITAI). The intervention aims to improve child and family mental health. A JITAI provides in-the-moment feedback to coach families.
- Trial name
- NCT06443918
- Testing
- A Just-in-Time Adaptive Intervention for Child and Family Mental Health
- Where
- 2 sites in United States
- Volunteers
- 347 people
- Sponsor
- Colliga Apps Corp.
Attention-Deficit Hyperactivity Disorder
A Phase II, Adaptive Trial Design Examining the Pharmacokinetic and Pharmacodynamic Effects of Modified Release Amphetamine (HLD100, Formulations B, C and E)) in Adolescents and Children With Attention-Deficit Hyperactivity Disorder (ADHD)
The main purpose of this study is to determine the rate and extent of absorption of one or more modified release formulations of amphetamine (HLD100) in both adolescents and children with ADHD.
- Trial name
- NCT01886469
- Testing
- HLD100-B, HLD100-C, HLD100-E
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
State Anxiety, Psychological Stress
Can Increased Medical Competence Reduce State Anxiety in Junior Doctors in the Emergency Department?
This randomized controlled trial investigates whether an adaptive e-learning program on acute and time critical medical conditions can reduce state anxiety and improve the competence of junior doctors working in emergency…
- Conditions
- State Anxiety, Psychological Stress, Education, Medical, E-learning
- Trial name
- MINDED (NCT06842394)
- Testing
- Adaptive E-learning
- Where
- Denmark
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Cardiac Arrest
Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Cardiac arrest is a sudden, unexpected loss of heart function. Therapeutic hypothermia, in which the body's temperature is lowered and maintained several degrees below normal for a period of time, has been used to successfully…
- Trial name
- THAPCA-IH (NCT00880087)
- Testing
- Therapeutic Hypothermia, Therapeutic Normothermia
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 329 people
- Sponsor
- University of Michigan
Contraception, Contraception Behavior
A Randomized-Controlled Trial to Increase the Uptake of LARCs in Cameroon
Cameroon exhibits a high and non-decreasing level of maternal mortality (roughly 600 per 100,000 live births), partially related to its relatively high total fertility rate (roughly 4.6).
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Contraceptive Method Switching
- Trial name
- HGOPY (NCT03733678)
- Testing
- Price discounts for SARCs, Price discounts for LARCs, Sequential vs. simultaneous recommendations
- Where
- Cameroon
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- World Bank
Anxiety, Anxiety Disorders
Implementation of a Just-In-Time Adaptive Intervention for Adolescent Anxiety
The goal of this clinical trial is to evaluate a smartphone based just-in-time adaptive intervention (JITAI) tool to deliver somatic behavioral recommendations for anxiety management among youth.
- Conditions
- Anxiety, Anxiety Disorders, Anxiety Disorder of Childhood
- Trial name
- NCT06946823
- Testing
- Just-In-Time Adaptive Intervention for Adolescent Anxiety
- Volunteers
- 50 people
- Sponsor
- Trustees of Dartmouth College