Clinical trials: Adipose Tissue-derived Stem Cell
Infantile Spinal Muscular Atrophy, Type I [Werdnig- Hoffman]
Allogeneic Adipose Derived Stem Cells for Werdnig Hoffman Patients
Spinal Muscular Atrophy (SMA) is an autosomal recessive disease of motor neurons. In the early 1980s, Werdnig from Vienna University and Hoffman from Heidelberg University described this disorder.
- Trial name
- NCT02855112
- Testing
- Adipose derived mesenchymal stem cell
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Tehran University of Medical Sciences
Type 1 Diabetes Mellitus
Mesenchymal Stem Cells in Patients With Type 1 Diabetes Mellitus
In this prospective, dual-center, open trial, patients with recent onset type 1 diabetes will receive one dose of allogenic Adipose tissue-derived stromal/stem cells (1x106 cells/kg) and oral cholecalciferol 2000UI/day for 24…
- Trial name
- NCT03920397
- Testing
- Infusion of adipose tissue-derived stem/stromal cells and oral Cholecalciferol supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Osteoarthritis, Genu Varum
Clinical Outcomes of Open Wedge High Tibial Osteotomy With Autologous Bone Marrow or Adipose-derived Stem Cell Therapy
The purpose of this research is to confirm the efficacy of cartilage regeneration (or stem cell transplant) simultaneously performed with high tibial osteotomy.
- Trial name
- HTOSC (NCT02642848)
- Testing
- HTO with microfracture, Transplantation of bone marrow stem cell, Transplantation of adipose derived stem cell
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Dongsik Chae
Severe Aplastic Anemia
Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia
RATIONALE: It has been shown that about 30% of patients do not respond to immunosuppressive therapy or experience recurrence, and graft rejection and graft-versus-host-disease (GVHD) decrease event-free survival to 30% to 50% in…
- Trial name
- NCT02407470
- Testing
- Rabbit antithymoglobulin (ATG), Adipose derived mesenchymal stem cells ( AD-MSCs), AD-MSC transdifferentiated HSCs (AD-HSCs)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Navy General Hospital, Beijing
Knee Osteoarthritis
Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells
The purpose of this study is to explore the efficacy and safety of autologous adipose mesenchymal stem cells in the treatment of early knee arthritis.
- Trial name
- NCT03956719
- Testing
- Autologous adipose-derived mesenchymal stem cells, abdominal liposuction
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Qilu Hospital of Shandong University
COVID-19
Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as treatment for patients suspected to have COVID-19.
- Trial name
- NCT04362189
- Testing
- HB-adMSC
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Hope Biosciences Research Foundation
COVID-19
A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04348435
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I
Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia
Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I, Fibromyalgia
- Trial name
- ADcSVF-CRPS (NCT02987855)
- Testing
- Lipoaspiration, ADcSVF isolation, Normal Saline IV
- Where
- 2 sites in United States, Honduras
- Sponsor
- Healeon Medical Inc
Combination of SVF and PRP for Androgenetic Alopecia
Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia
Androgenetic alopecia (AGA) is a common form of hair loss in both men and women, characterized by progressive patterned loss of hair from the scalp.
- Trial name
- AGA (NCT02865421)
- Testing
- stem cells, platelet rich plasma
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Alzheimer Disease
Autologous Human Adipose-Derived Mesenchymal Stem Cells in Alzheimer's Disease
This is a single patient emergency expanded access clinical study to assess the safety of administering autologous AdMSCs to an incurable Alzheimer disease patient.
- Trial name
- NCT04855955
- Testing
- Adipose-Derived Mesenchymal Stem Cells
- Sponsor
- Celltex Therapeutics Corporation
Adypose Mesenchimal Stem Cell, Ligament Rupture
Regeneration of Posterior Cruciate Ligament Injury Using Hypoxic Conditioned Allogenic Adipose Mesenchymal Stem Cell and Condition Medium
Transplantation of Allogenic Adipose Mesenchimal Stem cell in hypoxic cultur condition with Ligament- derived conitioned medium can enhance regeneration of posterior cruciate ligament rupture
- Conditions
- Adypose Mesenchimal Stem Cell, Ligament Rupture, Ligament Derived Conditined Medium
- Trial name
- NCT04889963
- Testing
- adypose mesenchymal conditioned medium and ligament derived conditioned medium
- Where
- Indonesia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Cerebral Palsy
Safety and Effectiveness of Autologous Adipose Tissue Derived Mesenchymal Stem Cell Implantation in Patients With CP
Safety and Effectiveness of Autologous Adipose Tissue Derived mesenchymal Stem Cell Implantation in Patients with CP
- Trial name
- CP (NCT03979898)
- Testing
- ASTROSTEM
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- R-Bio
ED, Adipose Derived Stem Cells
Can Adipose Derived Regenrative Cells be Used for Treating Erectile Dysfunction After Radical Prostatectomy
The goal of this study was to investigate if adipose derived regenerative cells can be used as a treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT07355530
- Testing
- Adipose-Derived Regenerative Cells
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Refractory Epilepsy
Intrathecal Autologous ADRC Treatment of Autoimmune Refractory Epilepsy
Refractory epilepsies caused by an autoimmune mechanisms lead in children to progressive neurodegeneration. Immunomodulation therapy is effective only in a half of such cases. New approaches are undertaken.
- Trial name
- EPIMSC (NCT03676569)
- Testing
- ADRC transplantation in autoimmune refractory epilepsy
- Volunteers
- 6 people
- Sponsor
- Mossakowski Medical Research Centre Polish Academy of Sciences
Autism
Adipose Derived Stem Cell Therapy for Autism
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Autism.
- Trial name
- NCT01502488
- Testing
- Fat Harvesting and Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Adipose-derived Stem Cells, Excimer Light
Adipose-derived Stem Cells Combined With Excimer Light in the Treatment of Stable Vitiligo
This study aimed to assess the efficacy and safety of intradermal injection of adipose-derived stem cells, alone and combined with excimer light in treatment of stable vitiligo.
- Conditions
- Adipose-derived Stem Cells, Excimer Light, Stable Vitiligo
- Trial name
- NCT07690501
- Testing
- Adipose-derived Stem Cells Combined With Excimer Light
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Tanta University
COVID-19
A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19
Hope Biosciences is conducting a research study of an investigational product called autologous adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04349631
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
Acute Traumatic Spinal Cord Injury
Safety and Preliminary Efficacy of FAB117-HC in Patients With Acute Traumatic Spinal Cord Injury
The main objective of the study is the evaluation of the safety and tolerability of FAB117-HC (a medicinal product containing human allogeneic adipose derived adult mesenchymal stem cells expanded and pulsed with H2O2, HC016…
- Trial name
- SPINE (NCT02917291)
- Testing
- FAB117-HC, Control group
- Where
- 9 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Ferrer Internacional S.A.
Type 1 Diabetes
Evaluate Safety of Adipose Derived Mesenchymal Stem Cell Transplantation for Type 1 Diabetes Treatment
The purpose of this study is to evaluate the safety of intravenously (IV) administered adipose-derived mesenchymal stem cell (AD-MSC) in patients with type 1 diabetes mellitus (T1D)
- Trial name
- NCT05308836
- Testing
- adipose-derived messenchymal stem cell
- Where
- Vietnam
- Volunteers
- 10 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Cleft of Alveolar Ridge
Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone in Alveolar Cleft Osteoplasty
Our aim was to combine regenerative techniques with bone grafting in human models to increase predictability and survival of reconstructed tissue.
- Trial name
- NCT02859025
- Testing
- anterior iliac crest graft, lateral ramus cortical bone+BFPSC+NBBM, anterior iliac crest graft+BFPSC+NBBM
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Shahid Beheshti University of Medical Sciences