Clinical trials: Adipose Tissue-derived Stem Cell
Cerebral Palsy
Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for the Treatment of Cerebral Palsy
This is an Individual Patient Expanded Access Protocol of Autologous HB-adMSCs for the Treatment of Cerebral Palsy (CP) with the primary goal of treating 1 individual with CP who has exhausted all treatment options, his condition…
- Trial name
- NCT04029896
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Rotator Cuff Tear, Lateral Epicondylitis
Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells
This study was a single-center, randomized, single-blind clinical trial. We plan to include 100 patients who met exclusion criteria of rotator cuff and lateral epicondylosis (tennis elbow) respectively by MRT or ultrasonography.
- Trial name
- NCT03279796
- Testing
- Autologous adipose-derived MSCs, Compound betamethasone
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Corona Virus Infection, Covid19
Clinical Study for Subjects With COVID-19 Using Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells
This is an interventional new drug clinical trial for a Phase 2 randomized, double-blind, and placebo control study using intravenous injection of allogeneic adipose stem cells (Celltex AdMSCs) for subjects with severe COVID-19.
- Trial name
- AdMSCs (NCT05017298)
- Testing
- Allogeneic adipose-derived stem cells
- Volunteers
- 30 people
- Sponsor
- Celltex Therapeutics Corporation
Low Back Pain
Autologous Adipose Derived Stem Cell Therapy for Intervertebral Disc Degeneration
1. Subject: 10 patients : Chronic low back pain patients with lumbar intervertebral disc degeneration 2. Investigational Product : Autologous adipose derived mesenchymal stem cells plus hyaluronic acid derivatives (Tissuefill) 3.
- Trial name
- NCT02338271
- Testing
- autologous adipose derived mesenchymal stem cell
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Inbo Han
Frailty Syndrome, Aging
Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)
This is a Phase I, open-label, non-randomized clinical trial to evaluate the safety and preliminary efficacy of adipose-derived mesenchymal stem cell secretome capsules (VinVital) in patients with frailty syndrome.
- Trial name
- VinVital (NCT07856602)
- Testing
- VinVital
- Volunteers
- 20 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Keratopathy
Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)
Evaluate the use of the autologous ASC for the treatment of bilateral limbic associated keratopathy
- Trial name
- HULPOFT (NCT01808378)
- Testing
- Expanded adipose-derived stem cells
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Dry Eye, Kerato Conjunctivitis Sicca
Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Disease
The objective of this study is to assess the safety and feasibility of allogeneic adipose tissue-derived mesenchymal stem cells (ASCs) injected into the lacrimal gland in a smaller groups of 7 patients with Aqueous Deficient Dry…
- Conditions
- Dry Eye, Kerato Conjunctivitis Sicca, Aqueous Tear Deficiency
- Trial name
- MESADDE (NCT03878628)
- Testing
- Adipose tissue-derived mesenchymal stem cells
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Peripheral Vascular Diseases, Cardiovascular Diseases
Adipose CELL Derived Regenerative Endothelial Angiogenic Medicine
The main purpose of this study is to evaluate the safety and feasibility of regenerative therapy with expanded adipose derived stroma/stem cells sue, administered intramuscularly in patients with critical leg ischemia.
- Trial name
- ACELLDREAM (NCT01211028)
- Testing
- Expanded autologous ASCs
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Toulouse
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Idiopathic Parkinson's Disease
Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's Disease
Primary Objective: To assess the safety profile of autologous MitoCell administered to subjects with idiopathic Parkinson's disease (PD) Secondary Objective: To explore the efficacy and safety of MitoCell given as the recommended…
- Trial name
- NCT05094011
- Testing
- Aadipose-Derived Mesenchymal Stem Cells
- Volunteers
- 9 people
- Sponsor
- Taiwan Mitochondrion Applied Technology Co., Ltd.
Crohn
Study of Allogenic Adipose-derived Stem Cells in Crohn's Fistula
Adipose-derived stem cells have properties of differentiation to various types of cells, immunomodulatory effects. adipose-derived stem cells (ASCs) show also low immunogenicity.
- Trial name
- ALLO-ASC (NCT01440699)
- Testing
- Allogenic human adipose-derived stem cells
- Where
- 3 sites in South Korea
- Volunteers
- 6 people
- Sponsor
- Anterogen Co., Ltd.
Crohn's Disease
Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)
The purpose of this study is to evaluate the combined remission of complex perianal fistulas, defined as the clinical assessment at Week 24 of closure of all treated external openings that were draining at baseline despite gentle…
- Trial name
- ADMIRE-CD-II (NCT03279081)
- Testing
- Cx601
- Where
- 159 sites in United States, Belgium and 13 more
- Volunteers
- 568 people
- Sponsor
- Tigenix S.A.U.
Anterior Cruciate Ligament Partial Rupture
Effectiveness and Safety of Autologous ADRC for Treatment of Anterior Cruciate Ligament Partial Rupture
Autologous adipose-derived regenerative cells (ADRC) will be extracted using Celution 800/CRS System (Cytori Therapeutics Inc) from a portion of the fat harvested from the patient's front abdominal wall.
- Trial name
- NCT02469792
- Testing
- Liposuction, ADRC isolation, Arthroscopic surgery
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Atopic Dermatitis
Study of ADSTEM Injection for Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis
Study of ADSTEM Injection for Patients with Moderate to Severe Subacute and Chronic Atopic Dermatitis
- Trial name
- ADSTEM Inj (NCT07377838)
- Testing
- ADSTEM Inj.
- Volunteers
- 286 people
- Sponsor
- EHL Bio Co., Ltd.
Overweight
Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds
The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts.
- Trial name
- NCT01218945
- Testing
- Cell Culture
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- University of Zurich
Amyotrophic Lateral Sclerosis
Compassionate Treatment : An Exploratory Clinical Trial to Assess Treatment of Amyotrophic Lateral Sclerosis
The purpose of the study is to determine the safety and possible effectiveness of Autologous Adipose-Tissue Derived Stem Cells treatment in a Amyotrophic Lateral Sclerosis(ALS) patient.
- Trial name
- NCT02383654
- Testing
- Autologous Adipose-Tissue Derived Stem Cells
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- China Medical University Hospital
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)
The goal of this prospective observational study is to evaluate whether injections of stem cells derived from the patient's own fat tissue (adipose tissue) can improve erectile function in men aged 30 to 75 who have erectile…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- RISE (NCT06605508)
- Testing
- Autologous Adipose Tissue-Derived Stem Cell Injection for Erectile Dysfunction, Stem cell-derived Exosomes Injection for Erectile Dysfunction
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Jumeirah American Clinic
Covid19
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 "Long Haul" Pulmonary Compromise
This is a Phase 1b study to assess the safety and efficacy of COVI-MSC in treating post COVID-19 "long haulers" with pulmonary compromise.
- Trial name
- NCT04909892
- Testing
- COVI-MSC
- Sponsor
- Sorrento Therapeutics, Inc.
Moderate to Severe Chronic Kidney Disease
Adipose-derived Stem Cells (ADSCs) for Moderate to Severe Chronic Kidney Disease
1. To assess the safety of allogeneic injection of expanded ADSCs to patients with Moderate to Severe Chronic Kidney Disease 2. To assess the efficacy of allogeneic injection of expanded ADSCs to patients with Moderate to Severe…
- Trial name
- NCT02933827
- Testing
- ELIXCYTE
- Where
- 3 sites in Taiwan
- Volunteers
- 39 people
- Sponsor
- UnicoCell Biomed CO. LTD
Bacterial Pneumonia
Cx611-0204 SEPCELL Study
The purpose of this randomised, multicentre, double-blind, placebo-controlled, phase Ib/IIa study is to assess the safety, tolerability and efficacy of eASCs (Cx611) administered intravenously as adjunctive therapy, therefore in…
- Trial name
- SEPCELL (NCT03158727)
- Testing
- Cx611
- Where
- 33 sites in Belgium, France and 4 more
- Volunteers
- 84 people
- Sponsor
- Tigenix S.A.U.