Clinical trials: Adolescents With Obesity
Prader-Willi Syndrome, Hyperphagia
Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
The investigators propose a randomized double-blind 8 week treatment trial of intranasal oxytocin (IN-OXT) vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect on (1) Eating behaviors (2)…
- Trial name
- OXT-PWS (NCT02629991)
- Testing
- Intranasal Oxytocin (IN-OXT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Adolescent Overweight, Adolescent Obesity
Improving Sleep, Decision-Making, and Eating in Adolescents With Obesity
This study is being performed to understand the effects of a lifestyle modification and sleep intervention on weight loss outcomes in adolescence.
- Conditions
- Adolescent Overweight, Adolescent Obesity, Sleep, Eating Behaviors
- Trial name
- STAR (NCT06745570)
- Testing
- Lifestyle Modification and Sleep Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Obesity
A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity
A phase II, randomized, double-blind, placebo-controlled, in parallel groups clinical trial to assess the safety and efficacy of dietary supplementation with tryptophan to achieve weight loss, and its neuropsychological effects…
- Trial name
- NCT02612259
- Testing
- TRYPTOPHAN
- Volunteers
- 44 people
- Sponsor
- Fundació Sant Joan de Déu
Obese Adolescents, Obesity
A Study of XW003 Injection in Chinese Adolescents With Obesity
The aim of the study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XW003 injection in Chinese adolescents with obesity
- Trial name
- NCT07143227
- Testing
- XW003 injection
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Physical Inactivity, Obesity
Factors Associated With Physical Inactivity Among Adolescents
Despite the acknowledgment that physical activity is important for health, there are still few population-based or school-based studies that uses the current physical activity guidelines for adolescents.
- Conditions
- Physical Inactivity, Obesity, Overweight
- Trial name
- FAPIA (NCT01137227)
- Where
- Brazil
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Obesity
Double-blinded, 6 Months Study With Bydureon® or Placebo in Adolescents With Obesity to Explore Changes in BMI
Combat-JUDO (Combating Juvenile Diabetes and Obesity through normalization of beta-cell function) is part of a collaborative project funded by the Seventh Framework Programme of the European Commission aiming to develop…
- Trial name
- Combat-JUDO (NCT02794402)
- Testing
- Exenatide
- Where
- 2 sites in Austria, Sweden
- Volunteers
- 44 people
- Sponsor
- Uppsala University
Psoriasis, Obesity
Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
Hypothesis 1: Patients with psoriasis will have clinical and laboratory assessments differing from control patients. Hypothesis 2: Patients with psoriasis will have laboratory alterations that correlate with other clinical…
- Conditions
- Psoriasis, Obesity, Cardiovascular Risk, Inflammation
- Trial name
- NCT01122095
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Bipolar Disorder
Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
A prospective, large, pragmatic, randomized trial to study the impact of METFORMIN and healthy lifestyle intervention (LIFE) vs.
- Trial name
- MOBILITY (NCT02515773)
- Testing
- Metformin, healthy lifestyle intervention (LIFE)
- Where
- 29 sites in United States
- Volunteers
- 1,565 people
- Sponsor
- Melissa Delbello
Polycystic Ovary Syndrome, Obesity
Two Different Dietary Interventions for Girls With Polycystic Ovary Syndrome
This study was conducted to evaluate the efficacy of the MEtabolic Syndrome REduction in NAvarra (RESMENA) diet versus a control diet based on American Heart Association (AHA) recommendations for the treatment of PCOS in…
- Conditions
- Polycystic Ovary Syndrome, Obesity, Androgen; Hypersecretion, Diet, Healthy
- Trial name
- NCT05768724
- Testing
- intervention diet, control diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pediatric Obesity, Type 2 Diabetes
Time Limited Eating in Adolescents With Type 2 Diabetes (KT2D)
To find the effectiveness of a diet plan (Time Limited Eating or TLE) on glycemic control, B-cell function, body fat, and body mass index (BMI) in adolescents with type 2 diabetes.
- Conditions
- Pediatric Obesity, Type 2 Diabetes, Time Restricted Eating
- Trial name
- NCT04536480
- Testing
- Time Limited Eating, Components Common to All Study Arms., Control
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Children's Hospital Los Angeles
Hypothalamic Obesity, Hypothalamic Tumor
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant form of obesity have excess rates of metabolic sequelae compared to…
- Conditions
- Hypothalamic Obesity, Hypothalamic Tumor, Craniopharyngioma
- Trial name
- NCT06299891
- Testing
- Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Obesity, Binge-Eating Disorder
Emotion Regulation and Binge Eating in Youth With Obesity
This study will investigate neural activation patterns in emotion- and cognition-related brain regions during an emotion regulation task involving cognitive reappraisal, and their associations with age and pubertal status, among…
- Trial name
- NCT02783872
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
CONTROL Condition, Exercise
Effect of Acute Exercise on Sensory and Hedonic Responses to a Fixed Meal in Adolescents With Obesity
While long considered independently, energy expenditure and energy intake have been shown to interact. Fot the last 20 years, the litterature has been describing tyhe effects of an acute bout of exercise on subsequent energy…
- Trial name
- SMASH (NCT06017440)
- Testing
- EXERCISE, CONTROL
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity
Effectiveness of Adapted Basketball Programs in Adolescents With Obesity (ABBA)
This study aims to evaluate the effects of different basketball training programs on adolescents with obesity. The objective is to assess how these programs influence body weight, physical fitness, motivation to exercise, and…
- Trial name
- ABBA (NCT07046871)
- Testing
- 1. Intervention Name (Arm 1) Name: Adapted Basketball Program with Video Support Type: Behavioral Description: A 7-week basketball intervention for adolescents with obesity, combining pedagogically a, ADAPT Adapted Basketball Program
- Where
- Tunisia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
The prevalence of childhood obesity in the United States has more than tripled in the past four decades affecting one in every five adolescent girls and is disproportionally higher among racial and/or ethnic minorities.
- Trial name
- NCT07169136
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Obesity, Childhood, Diet, Healthy
Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity
This study will address the following aims: Aim 1: Conduct an 8-week pilot RCT to examine the effects of a whole foods diet intervention on body adiposity in adolescents with obesity.
- Conditions
- Obesity, Childhood, Diet, Healthy, Body Weight Changes
- Trial name
- NCT06464497
- Testing
- Whole Foods MyPlate Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Adolescent Obesity, Adolescent Overweight
Helping Educate and Advance Learning Through Healthy Bite-Sized Eating Strategies
The goal of this clinical trial is to compare the effectiveness of a mobile health intervention in adolescents (14-17 years) with overweight or obesity.
- Conditions
- Adolescent Obesity, Adolescent Overweight, Diet, Healthy
- Trial name
- HEALTHY BITES (NCT06082830)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital of Philadelphia
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Girls and women 12-35 years old with obesity and polycystic ovarian syndrome who are on or off metformin, will receive a glucagon like peptide-1 receptor agonist intervention for 10 months to induce metabolic changes, weight loss…
- Trial name
- RESTORE (NCT05819853)
- Testing
- Semaglutide Injectable Product (Wegovy and/or Ozempic)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Childhood Obesity, Dyslipidemia
Nutritional Treatment of Overweight Adolescents With Cardiovascular Risk Factors (PowerUp)
This study is designed to evaluate the efficacy of two diets, a low glycemic load diet and a low saturated fat diet, in the treatment of adolescents with some heart disease risk factors associated with being overweight, such as…
- Conditions
- Childhood Obesity, Dyslipidemia, Insulin Resistance, Hypertension
- Trial name
- NCT00477477
- Testing
- Diet
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Boston Children's Hospital