Clinical trials: Advanced Age, open to volunteers
Ulcerative Colitis (Disorder)
Efficacy and Safety of Etrasimod in Elderly Patients With Ulcerative Colitis
Eligible patients will be identified in regular clinical practice. After providing thorough explanation and obtaining voluntary written informed consent, the clinical course, adverse events, endoscopic findings, and…
- Trial name
- NCT07243639
- Testing
- Etrasimod administration
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Showa Inan General Hospital
Coronary Disease, Heart Diseases
Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)
This international, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) compared to dual antiplatelet therapy (DAPT) in elderly or high bleeding risk patients…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Myocardial Ischemia
- Trial name
- PIV-EPIC (NCT06535568)
- Testing
- Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT)
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Lower Extremity Muscle Strength
Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease
This is a pilot trial of a 16-week physical activity and power training program among up to 30 Veterans/arm with advanced chronic kidney disease. The trial aims to test whether the program is tolerable to Veterans.
- Trial name
- NCT06089057
- Testing
- Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease, Attention Control for Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Guideline Implementation, Physiotherapy
Physiotherapy Practice in Flemish Nursing Homes
The goal of this observational study is to evaluate the extent to which physiotherapy sessions in Flemish nursing homes adhere to the IAGG-GARN guidelines and to explore factors influencing clinical practice among…
- Conditions
- Guideline Implementation, Physiotherapy, Nursing Homes, Focus Group
- Trial name
- NCT07576751
- Testing
- Mapping therapy sessions
- Where
- 4 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Enhance Care to Victims of Violence
Testing and Evaluating a Psychoeducation Tool and Guidelines for Victims of Violence in Belgian Hospitals.
The "Operation Alert/Operatie Alert/Opération Alerte" project, developed by UGent-ICRH and UZGent with funding from the Belgian Federal Public Service for Health, focuses on strengthening basic competencies to better and more…
- Trial name
- Operatie Alert (NCT06780540)
- Testing
- Operation Alert: Support prgram
- Where
- 10 sites in Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Ventilator-Induced Lung Injury
Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.
1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. 2.
- Trial name
- NCT06367946
- Testing
- mechanical ventilation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Long Term Care Homes, Malnutrition Elderly
CHOICE+ Quality Improvement for Long Term Care Homes
CHOICE+ is an eLearning program that empowers staff to improve the mealtime experience of long-term care (LTC) residents. This program is based on principles that align with relationship-centered care and promote resident quality…
- Conditions
- Long Term Care Homes, Malnutrition Elderly, Malnutrition Risk in Elder
- Trial name
- CHOICE+ (NCT07505407)
- Testing
- CHOICE+ virtual training program
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Waterloo
Sleep Disturbance
Sleep Detection in Residents of Long-term Care Facilities
Sleep disorders are common among older people. People who suffer from sleep disorders typically have difficulty falling asleep, staying asleep, wake up early and do not get restful sleep.
- Trial name
- NCT07819409
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eastern Switzerland University of Applied Sciences
Physical Fitness in Older Adults, Exercise Program
"Bliib Fit - Mach Mit!" in Residential Care Facilities
The goal of this clinical trial is to learn, if the video-based exercise program "Bliib fit - mach mit!" can be used to improve physical fitness in older adults living in residential care facilities.
- Trial name
- NCT06738186
- Testing
- Video-based exercise program, Caregiver-led activation program
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eastern Switzerland University of Applied Sciences
Chronic Intestinal Insufficiency, Advanced Glycation and Products
AGE Accumulation in Patients on Long-term Parenteral Nutrition
This prospective and observational study aims to evaluate the accumulation of advanced glycation end-products (AGEs) in adult and pediatric patients starting long-term parenteral nutrition, by non-invasive skin AGE measurements…
- Conditions
- Chronic Intestinal Insufficiency, Advanced Glycation and Products, Parenteral Nutrition
- Trial name
- NUPARAGE2 (NCT07392801)
- Testing
- Non-invasive skin AGE measurements
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations
Comparison of Dairy and Plant-based Alternatives in Adolescents and Older Adults
The purpose of the Dairy vs Plant study is to compare the effects of dairy and plant-based alternative products on blood sugar regulation and nutrient quality in adolescents and older adults.
- Conditions
- Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations, Appetite Regulation
- Trial name
- NCT06874400
- Testing
- Dairy, Plant-based alternative
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Solid Tumors Harboring MET Amplification
A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events and change in disease activity of telisotuzumab adizutecan.
- Trial name
- NCT07196644
- Testing
- Telisotuzumab Adizutecan
- Where
- 38 sites in United States, Israel and 3 more
- Volunteers
- 100 people
- Sponsor
- AbbVie
Frail Elderly, Frailty
Frailty Training for Emergency Nurses: A Cluster RCT in Morocco
This study tests whether a training program helps nurses better recognize and care for older adults with frailty in hospital emergency departments.
- Trial name
- NCT07892612
- Testing
- Structured Educational Program on Geriatric Frailty
- Where
- Morocco
- Volunteers
- 144 people
- Sponsor
- Cadi Ayyad University
3-nil Buildings Seniors
Pilot Project on Enhancing Support for Hidden Elderly in the Three-nil Buildings and Old Tenement Buildings: Capacity Building & Impact Evaluation
The aims of this interventional study are of two-fold. First, the study aims to develop the capacity to facilitate the collaborating NGOs to address the social determinants of aging well for 3-N seniors.
- Trial name
- NCT07920328
- Testing
- Mapped intervention based on health status
- Where
- Hong Kong
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frailty in Older Adults, Functional Decline
Prevalence of Anticholinergics in Geriatric Patients With Acute Functional Deterioration
This study investigates the anticholinergic burden on patients seen in the Subacute mobile outpatient geriatric clinic in Aalborg, Denmark, between the years of 2024 and 2025.
- Conditions
- Frailty in Older Adults, Functional Decline, Anticholinergic Syndrome
- Trial name
- NCT07165574
- Testing
- No intervention as the study is observational
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital
UTI - Urinary Tract Infection
Urine Collection and Novel UTI Biomarkers in Children and Older Adults
Suspected urinary tract infection (UTI) is a common driver of antibiotic prescribing and hospital admission, yet accurate diagnosis remains challenging.
- Trial name
- COLLECT-UTI (NCT07766278)
- Where
- United Kingdom
- Volunteers
- 230 people
- Sponsor
- Queen's University, Belfast
Pneumococcal Vaccines, Immunosuppression
Evaluation of PCV21 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans
The investigators will evaluate the immune response of immunocompromised adults, who have previously received at least 1 dose of 23-valent pneumococcal polysaccharide vaccine, to the booster with of 21-valent pneumococcal…
- Trial name
- NCT06271681
- Testing
- 21-valent pneumococcal conjugate vaccine
- Volunteers
- 45 people
- Sponsor
- VA Sierra Nevada Health Care System
Acute Respiratory Infections (ARIs)
RSV in Acute Respiratory Infection Surveillance Among Community-Dwelling Elderly Aged ≥50 Years in China
This is a multicenter, prospective, observational, community-based study designed to evaluate the incidence of respiratory syncytial virus (RSV) infection among community-dwelling elderly individuals in China, as well as their…
- Trial name
- RAISE (NCT07075029)
- Testing
- NP swabs
- Where
- 13 sites in China
- Volunteers
- 28,800 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital