Clinical trials: Aggressive Behaviour
Autism, Intellectual Disabilities With Other Behavioral Symptoms
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation
The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors.
- Conditions
- Autism, Intellectual Disabilities With Other Behavioral Symptoms, Intellectual Disability
- Trial name
- RT-ID (NCT07624448)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cyberbullying
Bullying Prevention Intervention for Adolescent Primary Care Patients
The purpose of this randomized controlled study is to evaluate acceptability and feasibility, and to gather preliminary data about efficacy, of "iPACT" (intervention to Prevent Adolescent Cyber-victimization with Text messages)…
- Trial name
- iPACT (NCT03467009)
- Testing
- iPACT Intervention, Control: Enhanced Usual Care (EUC), iPACT Intervention- app
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Rhode Island Hospital
Autism Spectrum Disorder, Developmental Disability
Propranolol for Challenging Behaviors in Autism
Severe challenging behaviors such as aggression and self-injury can cause significant morbidity and decrease the quality of life for individuals with Autism Spectrum Disorders (ASD).
- Conditions
- Autism Spectrum Disorder, Developmental Disability, Aggression, Self-Injurious Behavior
- Trial name
- NCT04047355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rutgers, The State University of New Jersey
Oligodendroglioma
Proteomic Characterization of Aggressive Oligodendrogliomas
Oligodendrogliomas represent a distinct subgroup of adult gliomas characterized by specific molecular alterations (1p/19q codeletion, mutations of IDH, TERT promoter, CIC, FUBP1).
- Trial name
- PROGLIO (NCT04843085)
- Testing
- Proteomic analysis
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Hyperactivity Disorder (ADHD)
Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 1)
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of SPN-810 in the treatment of Impulsive Aggression (IA) in subjects with Attention-Deficit/Hyperactivity Disorder (ADHD) in conjunction with…
- Trial name
- NCT02618408
- Testing
- SPN-810 (18 mg), SPN-810 (36 mg)
- Where
- 28 sites in United States
- Volunteers
- 333 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Bullying, Cyberbullying
Using Digital Health Technology to Prevent Bullying and Cyberbullying Among Elementary School Students
This project is designed to address the urgent need for an effective primary prevention approach to the problem of bullying and cyberbullying among elementary school students.
- Conditions
- Bullying, Cyberbullying, Smoking
- Trial name
- NCT06592872
- Testing
- Bullying prevention
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Christopher Williams
Kidney Cancer
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00908739
- Testing
- gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Sponsor
- Case Comprehensive Cancer Center
Impulsive Aggression Comorbid With ADHD
A Study to Evaluate the Efficacy and Safety of SPN-810 as Adjunctive Therapy in Children With Impulsive Aggression Comorbid With Attention-Deficit/Hyperactivity Disorder (ADHD)
This will be a randomized, double-blind, placebo-controlled, dose-ranging, efficacy and safety study in children with impulsive aggression comorbid with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT01364662
- Testing
- SPN-810
- Where
- 27 sites in United States
- Volunteers
- 121 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Alzheimer's Disease, Agitation
Citalopram for Agitation in Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of citalopram for agitation in Alzheimer's dementia.
- Trial name
- CitAD (NCT00898807)
- Testing
- citalopram
- Where
- 8 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- JHSPH Center for Clinical Trials
Dating Violence, Dating Abuse
A Brief Intervention
This randomized controlled trial (RCT) study is a small scale test of the feasibility and preliminary efficacy of a brief motivational interview-style intervention.
- Trial name
- NCT01632176
- Testing
- Brief, motivational interview and one booster session
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston University
High-risk Aggressive Lymphoma After Auto-HSCT
Maintenance Therapy Post-HSCT in High-risk Aggressive Lymphoma
Relapse after autologous hematopoietic stem cell transplantation (ASCT) is still challenging for high-risk aggressive lymphoma. This study was to investigate the efficacy and safety of maintenance therapy post-ASCT.
- Trial name
- NCT03695055
- Testing
- Maintenance therapy post-HSCT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fujian Medical University
Childhood Trauma, Stress
Psychosocial Correlates of Trait Emotional Intelligence and Psychosomatic Symptoms Among Adolescents Exposed to Bullying and the Effects of Mindfulness-Based Stress Reduction.
This study examines the psychosocial correlates of trait emotional intelligence and psychosomatic symptoms among adolescents exposed to bullying and analyzes the effetiveness of Mindfulness Based Stress Reduction (MBSR) program…
- Conditions
- Childhood Trauma, Stress, Emotional Intelligence, Psychosomatic Disorders
- Trial name
- MBSR-RCT (NCT07694908)
- Testing
- Mindfulness Based Stress Reduction (MBSR)
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Fatima Jinnah Women University
Impulsive Aggression, ADHD
Dialectical Behavioral Therapy Skills for Impulsive Aggression
This trial aims to Study the efficacy of DBT skills for impulsive aggression and executive dysfunctions in drug naïve children who are presented with impulsive aggression and ADHD and attending Child and adolescent clinic at…
- Conditions
- Impulsive Aggression, ADHD, Executive Dysfunction
- Trial name
- NCT05351944
- Testing
- Dialectical behavioral therapy skills for the intervention experimental group A, psychoeducation or Atomoxetine or stimulants according to ADHD severity
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Alexandria University
Pituitary Tumor
PITUItary Carcinoma or Aggressive Tumors REgistry -Lyon
The purpose of this study is to observe predictors of pituitary tumor recurrence and markers of persistent disease activity through computerized collection of comprehensive demographic, therapeutic, pathologic and outcome…
- Trial name
- PITUICARE-Lyon (NCT02854228)
- Where
- France
- Volunteers
- 1,300 people
- Sponsor
- Hospices Civils de Lyon
Oppositional Defiant Disorder
Treatment of Children With Peer Related Aggressive Behavior
The efficacy of the Treatment Program for Children with Aggressive Behaviour (Therapieprogramm für Kinder mit aggressivem Verhalten, THAV) which is a social competence training delivered in an individual format will be evaluated…
- Trial name
- NCT01406067
- Testing
- Treatment Program for Children with Aggressive Behavior, Play group
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Cologne
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Dementia or a Related Disorder, Mental Health Diagnoses
Effectiveness and Implementation of Montessori Approaches in Person-Centered Care Within VA
Background: Addressing behavioral and neuropsychiatric symptoms of Veterans with dementia and serious mental illness (SMI) such as schizophrenia can be challenging for staff in VA long-term care settings, called Community Living…
- Conditions
- Dementia or a Related Disorder, Mental Health Diagnoses, Symptoms of Agitation or Aggression
- Trial name
- MAP-VA (NCT04829500)
- Testing
- Montessori Approaches to Person-Centered Care (MAP-VA)
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- VA Office of Research and Development
Lymphoma
SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00004031
- Testing
- rituximab, CHOP regimen, carmustine
- Where
- 15 sites in United States, Canada
- Volunteers
- 397 people
- Sponsor
- SWOG Cancer Research Network
Disruptive Behavior, Aggression Childhood
Digital Parent Training for Disruptive Behaviors in Children
This is an open pilot trial of web-based parent training for tantrums and disruptive behavior in children. Parents will be asked to complete a battery of tests to assess their children' behaviors before and after the…
- Conditions
- Disruptive Behavior, Aggression Childhood, Anger, Non-Compliance, Patient
- Trial name
- NCT03697837
- Testing
- Parent Management Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University