Clinical trials: Agitated Behaviour
Psychomotor Agitation
Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation
Compare the effects of intravenous midazolam and ketamine on emergence agitation after sevoflurane anesthesia
- Trial name
- NCT02256358
- Testing
- Midazolam, Ketamine
- Volunteers
- 68 people
- Sponsor
- Inje University
Behavioral Monitoring in ICU, Prediction of Accidental Events Using AI-Assisted Video Analysis
Exploring the Use of AI-Assisted Video Monitoring to Predict Accidental Events in ICU Patients
This study aims to improve the safety and care of patients in the Intensive Care Unit (ICU) by using artificial intelligence (AI) to analyze video monitoring.
- Conditions
- Behavioral Monitoring in ICU, Prediction of Accidental Events Using AI-Assisted Video Analysis, ICU Patient Safety and Early Warning System
- Trial name
- AIME-ICU (NCT07307521)
- Testing
- AI-Assisted Video Monitoring
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Alzheimer's Disease, Psychosis
Treatment of Psychosis and Agitation in Alzheimer's Disease
Clinically, many patients with AD show no response or minimal response to antipsychotics for symptoms of agitation/aggression or psychosis, or they have intolerable side effects on these medications.
- Conditions
- Alzheimer's Disease, Psychosis, Agitation
- Trial name
- NCT02129348
- Testing
- Lithium
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- New York State Psychiatric Institute
Alzheimer's Disease
CATIE-Alzheimer's Disease Trial
The CATIE Alzheimer's Disease Trial is part of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project. The study is for people with Alzheimer's disease who are having trouble with their thinking or…
- Trial name
- NCT00015548
- Testing
- Olanzapine, Quetiapine, Risperidone
- Where
- 34 sites in United States
- Volunteers
- 450 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anesthesia, Emergence Delirium
The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics
Some changes in the patient's cognitive state are observed during the recovery period from general anesthesia. This period of behavioral dysregulation has been called emergence agitation (EA) and emergence delirium (ED).
- Conditions
- Anesthesia, Emergence Delirium, Anesthesia Awareness, Behavior Child Problems
- Trial name
- NCT06323616
- Testing
- MAC adjustment to PSI between 25 and 50
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Brain Injuries, Craniocerebral Trauma
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI).
- Conditions
- Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
- Trial name
- NCT01322048
- Testing
- IV Propranolol and Per Tube Clonidine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Agitation in Adolescents and Young Adults With ASD
INP105 Proof-of-concept Study for the Acute Treatment of Agitation in Adolescents and Young Adults With ASD
This is a Phase 2a, proof-of concept, 2-way, 2-period crossover, double-blind study to evaluate the safety and efficacy of INP105 as an acute treatment versus placebo in adolescents and young adults with autism spectrum disorder…
- Trial name
- CALM 201 (NCT05163717)
- Testing
- INP105
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Impel Pharmaceuticals
Neuro-Degenerative Disease
Efficiency of E-learning and Role-playing for the Training of Nursing Home Caregivers in the Support of Agitation in Neurodegenerative Diseases
This study will investigate the effects of "I-Learn cognition and behaviour" training in the care in agitation in patients with neurodegenerative diseases.
- Trial name
- NCT04937127
- Testing
- I-LEARN training, usual care
- Where
- 7 sites in France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Tours
Psychomotor Agitation
Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?
Clonidine is widely used off-label in children for several indications. Clonidine is used for treatment and/or prevention of postoperative agitation in children anaesthetised with Sevoflurane.
- Trial name
- NCT02361476
- Testing
- Clonidine
- Where
- 3 sites in Denmark
- Volunteers
- 379 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sleep Disorders, Circadian Rhythm, Insomnia
Actigraphic Analysis of Treatment Response
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Insomnia, Psychomotor Agitation
- Trial name
- NCT00723580
- Testing
- risperidone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Agitation, Child
Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery
This study is a single-center, prospective, randomized, controlled trial. To investigate if preoperative using of eye patch will decrease emergence agitation, and to provide a better method of decreasing emergence agitation to…
- Conditions
- Agitation, Child, Anesthesia
- Trial name
- NCT02590744
- Testing
- eye patch, non-eye patch
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xiaoliang Gan
ADHD, Sleep Problems
A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep
The goal of this clinical trial is to learn if iron supplementation works to restless sleep in youth with ADHD. A second goal is to learn if iron supplementation helps to ease ADHD symptoms.
- Trial name
- NCT07061470
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Agitation
Scalp Nerve Block on Emergence Agitation
Emergence agitation is a common problem in children during recovery from sevoflurane anesthesia. Pain is considered as a cause of postoperative emergence agitation and compounding factor of agitation assessment in children.
- Trial name
- NCT02428283
- Testing
- Ropivacaine, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Ajou University School of Medicine
Agitation
Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type
The primary objective of this study is to evaluate the efficacy of DMTS on frequency and severity of agitation associated with dementia of the Alzheimer's type, compared with placebo.
- Trial name
- NCT06052254
- Testing
- 12 cm2 - 2 Active DMTS Patches
- Where
- 8 sites in United States
- Volunteers
- 150 people
- Sponsor
- Teikoku Pharma USA, Inc.
Iron Deficiency, Restless Leg Syndrome
Probiotics in the Treatment of Iron Deficiency in Children With Restless Leg Syndrome
A double-blind randomized controlled trial comparing iron plus vitamin C plus probiotic (lactobacillus plantarum 299) to iron plus vitamin C plus placebo in correcting the iron deficiency in children with Restless leg syndrome…
- Trial name
- NCT01617044
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
FOXP1 Syndrome
Psychiatric Phenotype Characterization of Individuals With FOXP1 Syndrome
FOXP1 syndrome is a rare genetic disorder with a variable phenotype, characterized somatically by facial dysmorphia, dysphagia, hypotonia, relative or real macrocephaly, which may be associated with cerebral, cardiac, urogenital…
- Trial name
- FOXP1-PP (NCT06211673)
- Testing
- Semi-structured interviews, Heteroquestionnaires
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Agitation
Midazolam Effect on Agitation Postnasal Surgery
Postoperative agitation is a common complication, it's incidence post head and neck surgery is around 11-26%. Avoiding such complication is mandatory to facilitate patient's recovery and reduce risk of postoperative agitation…
- Trial name
- NCT05165914
- Testing
- Intravenous midazolam before emergence from general anesthesia, Intravenous normal saline before emergence from general anesthesia
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jordanian Royal Medical Services
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Polysomnography, Sleep Apnea Syndromes
Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database
The primary purpose of the proposed study is to validate our previously developed predictive model for adults with obstructive sleep apnea using (i) clinical data from multiple large academic centers, (ii) a longer follow-up…
- Conditions
- Polysomnography, Sleep Apnea Syndromes, Risk Factors, Prognosis
- Trial name
- NCT03834792
- Testing
- No intervention but exposure
- Where
- Canada
- Volunteers
- 5,155 people
- Sponsor
- Ottawa Hospital Research Institute
Critical Illness
Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit
The objective of this study is to administer music therapy to patients in the pediatric intensive care unit (PICU) in order to observe how music affects patient agitation, vital signs, and overall recovery in the unit.
- Trial name
- NCT03453814
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- State University of New York at Buffalo