Clinical trials: Agitated Behaviour
Anxiety, Agitated Depression
The Effects of Music Listening on Anxiety and Agitation in People With Mild and Moderate Cognitive Impairment
Advancing age is associated with an increased risk of developing dementia which can lead to a rapid acceleration in both the healthcare costs and caregiver burden.
- Trial name
- NCT05858541
- Testing
- Music Listening, Listening to Audiobooks
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Southern California
Agitation,Psychomotor
A Multicomponent Intervention Program to Prevent and Reduce ICU Agitation and Physical Restraint Use
Despite deleterious effects, physical restraints are still commonly used in (expected to become) agitated patients in Dutch ICUs (20-25%).
- Trial name
- PRAISE (NCT05783505)
- Testing
- Multicomponent intervention program
- Where
- 5 sites in Netherlands
- Volunteers
- 480 people
- Sponsor
- Radboud University Medical Center
Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease
Addressing Dementia Via Agitation-Centered Evaluation
This is a multi-center, randomized, double-blind, placebo-controlled study, to assess the efficacy and safety of AXS-05 in the treatment of agitation in patients with Alzheimer's disease.
- Conditions
- Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease, Agitation,Psychomotor
- Trial name
- ADVANCE (NCT03226522)
- Testing
- AXS-05, Bupropion
- Where
- 78 sites in United States, Australia
- Volunteers
- 366 people
- Sponsor
- Axsome Therapeutics, Inc.
Acute Agitation
Safety and Tolerability of INP105 (Olanzapine by I231 POD® Device) Nasal Spray in Healthy Volunteers - SNAP 101
The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of INP105, which is an investigational drug-device combination product comprised of the drug component OLZ administered by a…
- Trial name
- SNAP101 (NCT03624322)
- Testing
- Zyprexa IM, Zydis, INP105
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Impel Pharmaceuticals
Schizophrenia
Staccato Loxapine in Agitation (Proof of Concept)
The purpose of this study is to assess efficacy and safety of Staccato Loxapine in the treatment of acute agitation in schizophrenic patients.
- Trial name
- NCT00369577
- Testing
- Inhaled Loxapine 5 mg, Inhaled Loxapine 10 mg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Akathisia
Akathisia in Post Operative Outpatients Surgery
The main objective of this study is to evaluate the incidence of akathisia with Droperidol, the prophylactic treatment of post operative nausea and vomiting, used at two different doses, versus control group (Ondansetron), in…
- Trial name
- NCT01942343
- Testing
- Droperidol 1,25 mg administration, Droperidol 0,625 mg administration, Odansetron 4 mg administration
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Agitation,Psychomotor
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation
This study designed to evaluate the correlation between the effect of intraoperative magnesium sulfate infusion and the incidence of emergence agitation after pediatric ophthalmic surgery
- Trial name
- NCT03208452
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Schizophrenia, Psychotic Disorders
Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone
To assess the effect of risperidone 2 mg daily (QD) on the differential sensitivity of 2 spatial working memory tests (the GMLT and MDR) in non-agitated, drug-naive patients suffering from first-episode…
- Trial name
- NCT00174200
- Testing
- Risperidone 2 mg
- Where
- 3 sites in Canada, Russia
- Volunteers
- 20 people
- Sponsor
- Pfizer
Alcohol Abuse, Alcoholism
Consequences of At-risk Alcohol Consumption in ICU Patients
At-risk drinking is known to cause a high incidence of alcohol withdrawal syndrome which has a high impact on morbidity and mortality.
- Trial name
- NCT03565016
- Testing
- no interventional study
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Therapeutic Touch
The Effect of Therapeutic Touch on Agitation, Pain, and Cortisol Levels in Intensive Care Patients
Intensive care units (ICU) are special clinical areas where advanced monitoring and treatment of patients with life-threatening organ failure or those at risk of developing organ failure are carried out, with high technological…
- Trial name
- NCT07061340
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Cervical Spondylosis
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant
The purpose of this study is to determine the recovery profiles after general anesthesia in patient undergoing anterior cervical spine surgery.
- Trial name
- NCT02819089
- Testing
- Dexmedetomidine, NSS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Dementia
Decoding Death and Dying in People With Dementia by Digital Thanotyping
How can healthcare professionals recognize that a person with dementia is at the end of life? When people are dying, their physical, mental, and social abilities are gradually declining.
- Trial name
- 5-D (NCT06437132)
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- University of Bergen
Dementia, Alzheimer's Disease
Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
The purpose of this trial is to test the safety \& tolerability of intramuscular aripiprazole in acutely agitated patients diagnosed with Dementia.
- Trial name
- NCT00095719
- Testing
- Aripiprazole
- Where
- 14 sites in United States
- Volunteers
- 125 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Response of Agitated Patients to Dexmedetomidine
Dexmedtomodine Effect on Agitated Psychotic Patients Suffer COPD
Many studies approved dexmedetomodine as a drug controlled agitation for psychotic patients and also for patients on non invasive ventilation.
- Trial name
- NCT06567587
- Testing
- Dexmedetomidine, BIPAP
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Dementia
Effect of "breath of Fresh Air" Flash Activity on Dementia Agitation : Pilot Study
Non-drug therapies (NDT) constitute a strong axis of the person with dementia behaviour management. Among these NDT, the flash activities constitute a mode of intervention to prevent and control the expression of the most…
- Trial name
- DEMACTIFLASH (NCT04094779)
- Testing
- Usual relation care, Flash activity "breath of fresh air"
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Toulouse
Delirium, Agitation
Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium
The purpose of this randomized clinical trial is to determine whether risperidone alone, trazodone alone, or a combination of risperidone and trazodone is superior for the treatment of ICU acquired delirium.
- Trial name
- NCT02118688
- Testing
- Risperidone, Trazodone
- Where
- United States
- Sponsor
- Rochester General Hospital
Central Venous Catheterization, Exposure to X-Rays
Agitated Saline Versus CXR Confirmation of Central Venous Lines
Central venous lines insertion are common procedures these days. CVL placed under USG guidance have high success rates and low complications even in developing country settings.
- Trial name
- NCT03442790
- Testing
- Agitated Saline Method, chest x-ray
- Volunteers
- 260 people
- Sponsor
- Nepal Mediciti Hospital
Alzheimer Dementia, Agitation,Psychomotor
Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)
This study will explore the effect of ECT treatments plus usual care (ECT+UC) in reducing severe agitation in patients with moderate to severe dementia including Alzheimer's Disease, Vascular dementia, Frontotemporal dementia…
- Trial name
- ECT-AD (NCT03926520)
- Testing
- Electroconvulsive Therapy (ECT)
- Where
- 5 sites in United States
- Volunteers
- 41 people
- Sponsor
- Brent Forester
Delirium, Locally Advanced Malignant Neoplasm
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care
This phase II/IIII trial studies how well haloperidol and lorazepam work in controlling symptoms of persistent agitated delirium in patients with cancer that has spread to other places in the body undergoing palliative care.
- Conditions
- Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT03743649
- Testing
- Haloperidol, Lorazepam, Quality-of-Life Assessment
- Where
- 3 sites in United States, Brazil
- Volunteers
- 110 people
- Sponsor
- M.D. Anderson Cancer Center