Clinical trials: Alcohol-related Disorders
Fetal Alcohol Spectrum Disorders
FASST - Fetal Alcohol Spectrum Stimulant Trial
This study is a double-blind, placebo controlled, series of N-of-1 trials of individualised stimulant dose on ADHD symptomatology in children with FASD.
- Trial name
- FASST (NCT04968522)
- Testing
- Methylphenidate Hydrochloride, Methylphenidate Hydrochloride 18 MG, Dexamphetamine sulfate
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Monash Medical Centre
Alcohol Abuse, Alcohol Drinking
TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda
The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
- Trial name
- TREAT C-AUD (NCT04743024)
- Where
- Uganda
- Volunteers
- 7,188 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Alcohol Use Disorder
Evaluating the Effectiveness of Implementation Intentions to Strengthen Approach-avoidance Training
Approach Bias Modifcation corresponds to computerized interventions designed to change a cognitive bias (i.e., the approach bias) that may contribute to the maintenance of Alcohol Use Disorder.
- Trial name
- IMBA (NCT06211959)
- Testing
- Approach Bias Modification with Implementation Intentions
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Clinique de la Mitterie
Alcoholic Hepatitis, Acute Liver Failure
Outcomes Using MARS for Patients With ALF
Retrospective chart review will be conducted on patients at Methodist Dallas Medical Center, meeting the inclusion criteria from January 1, 2019 to December 15, 2020 to determine the transplant free survival and overall survival…
- Trial name
- NCT05594953
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Methodist Health System
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Diabetes, Endocrine System Diseases
Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial
The Transition Navigator Trial (TNT) is a pragmatic randomized controlled trial evaluating the effectiveness of usual care plus a patient navigator service versus usual care plus newsletters and other educational materials, to…
- Conditions
- Diabetes, Endocrine System Diseases, Gastro-Intestinal Disorder, Neuro-Degenerative Disease
- Trial name
- TNT (NCT03342495)
- Testing
- Patient Navigator, Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 337 people
- Sponsor
- University of Calgary
Alcohol Addiction, Mouth Diseases
Testing Interventions to Reduce Alcohol Consumption Among Outpatients in a Dental Setting
The investigators wish to investigate the feasibility of using a web based drinking app (www.drinksmeter.com) to reduce alcohol consumption among patients attending an outpatient clinic in a dental setting.
- Trial name
- NCT02374905
- Testing
- Drinksmeter, Brief Advice of Alcohol Use
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Substance Abuse
Parent-Adolescent Interactions and Adolescent Development
The purpose of this study is to observe parent-adolescent interactions and to examine the parenting behaviors and adolescent emotional and physiological responses that are associated with youth's substance use.
- Trial name
- PAIT (NCT01572441)
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- George Mason University
Mental Health, Substance Use (Drugs, Alcohol)
Understanding Psychological Distress and Therapeutic Environment in the Emergency Department
This research aims to establish the number of patients coming to Emergency Departments (EDs) with issues relating to mental health, alcohol or drugs, or in some form of psychological distress, including those for whom this was…
- Conditions
- Mental Health, Substance Use (Drugs, Alcohol), Psychological Distress
- Trial name
- UPDATE-ED (NCT06655467)
- Testing
- Routine Care
- Where
- United Kingdom
- Volunteers
- 398 people
- Sponsor
- NHS Fife
Alcohol Dependence
Telephone-Based Continuing Care for Alcohol Dependence
Alcohol dependency is the second most common psychiatric disorder and a major public health concern. As addictive disorders and now thought to be chronic disorders for many patients there is a need for the development of expanded…
- Trial name
- NCT02030093
- Testing
- Telephone-based counseling
- Where
- Switzerland
- Volunteers
- 317 people
- Sponsor
- University of Bern
Fetal Alcohol Spectrum Disorders
Alcohol Use During Pregnancy in Finland According to Meconium Samples
Meconium samples are collected anonymously from newborns in Helsinki University Hospital maternity ward. The study tries to to find how many women continue to use alcohol during the second half of the pregnancy.
- Trial name
- RASMEK21 (NCT04918043)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hanna Kahila
Alcoholic Liver Disease
Gut Mycobiome Profile in Alcoholic Liver Disease.
The fecal mycobiome, which refers to the community of fungi that resides in the human gut, is an important component of the gut microbiome.
- Trial name
- NCT05793190
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Suicidal Ideation, Social Behavior
Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol
The objective of this study is to make a massive suicide risk and social behavior assessment in 24 pre-graduate education centers in Mexico City (approximately 30,000 students aged between 15 and 22 years), taking also into…
- Conditions
- Suicidal Ideation, Social Behavior, Depression, Depressive Disorder
- Trial name
- TEDUCA (NCT04067076)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 30,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Healthy Participants
Prevention of Hazardous Use of Alcohol with Danish High School Students (Our Choice)
The trial 'Our Choice' examines the effect of two prevention interventions targeting school, parent, and student levels at Danish high schools.
- Trial name
- NCT06018389
- Testing
- Structural only, Structural+Group MI
- Where
- Denmark
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fetal Alcohol Spectrum Disorder
Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy?
Urine sample and exhaled Nitric Oxide will analyzed and compared between children diagnosed with Fetal Alcohol Spectrum Disorder and healthy control. Pilot study- 5 children in each group
- Trial name
- NCT03802708
- Testing
- Metabolomic analysis urine sample
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Substance-Related Disorders
Medical Office Intervention for Adolescent Drug Use
The goal of this study is to assess the efficacy of a new intervention based on motivational enhancement therapy among adolescents with a history of substance use.
- Trial name
- NCT00229983
- Testing
- Motivational Enhancement Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Boston Children's Hospital
Fetal Alcohol Syndrome, Attention Deficit Hyperactivity Disorder (ADHD)
Open-Label Study of the Long Term Tolerability and Safety of Atomoxetine in Children With FASD and ADD/ADHD
Determine if atomoxetine is safe and well tolerated by children with fetal alcohol syndrome.
- Trial name
- B4Z-US-050 (NCT00418262)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Oklahoma
Cocaine Dependence, Opioid Dependence
FMRI of Stress and Addictive Disorders
The purpose of this study is to explore whether frontal brain activation in response to stress varies as a function of the presence or extent of early trauma and whether or not this effect is greater in women compared to men.
- Conditions
- Cocaine Dependence, Opioid Dependence, Alcoholism, Pathological Gamblers
- Trial name
- NCT01558973
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University