Clinical trials: Alpha-Tocopherol
Tetralogy of Fallot (TOF), Alpha-tocopherol
Effect of Parenteral Alpha-Tocopherol in the Definitive Surgery of Tetralogy of Fallot
Introduction: Tetralogy of Fallot (ToF) correction with cardiopulmonary bypass (CPB) poses a risk of ischemia-reperfusion injury, especially in cyanotic myocardium.
- Conditions
- Tetralogy of Fallot (TOF), Alpha-tocopherol, Cardiac Surgery
- Trial name
- NCT07194304
- Testing
- alpha-Tocopherol, Sterile Water for Injection
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Cancer, Neuropathy
Nutritional Supplement for Treating Chemotherapy Induced Neuropathy
Administration of a nutritional supplement containing palmitoyethanolamide, alpha lipoic acid, vitamin B12, vitamin B6 , vitamin B1, nicotinamide, magnesium, zinc, vitamin E, and superoxide of dismutase in individuals receiving…
- Conditions
- Cancer, Neuropathy, Chemotherapy Induced Pain Neuropathy, Chemotherapy-Induced Peripheral Neuropathy
- Trial name
- NCT07022938
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 71 people
- Sponsor
- Aristotle University Of Thessaloniki
Beta Thalassemia Major Anemia, Hemolysis
The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia Major
The accumulation of unpaired α-globin chains in β-thalassemia major patients may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia.
- Conditions
- Beta Thalassemia Major Anemia, Hemolysis, Oxidative Stress
- Trial name
- NCT03948737
- Testing
- Alpha-Tocopherol
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Burn
Vitamin E Supplementation in Burned Patients
A dietary antioxidant, alpha-tocopherol, will be used to potentially attenuate Vitamin E short- and long-term losses in plasma and adipose, reverse the oxidative stress of burn injury and, in the process, decrease the secondary…
- Trial name
- NCT01749371
- Testing
- Vitamin E
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Breast Cancer, Lymphedema
Vitamin E and Pentoxifylline in Treating Women With Lymphedema After Radiation Therapy for Breast Cancer
RATIONALE: Vitamin E and pentoxifylline may be effective in decreasing lymphedema in women who have received radiation therapy for breast cancer.
- Trial name
- NCT00022204
- Testing
- vitamin E, pentoxifylline, quality-of-life assessment
- Where
- United Kingdom
- Sponsor
- Royal Marsden NHS Foundation Trust
Fragile X Syndrome
Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome
The Fragile X syndrome (FXS) was first described by Dr. Martin and Dr. Bell in 1943, in families with several patients affected by sex-linked mental disability.
- Trial name
- SXF-TRA152 (NCT01329770)
- Testing
- Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Yolanda de Diego Otero
Complementary Feeding Recommendation, Linear Programming,
Effect of Enhanced Counseling Using Complementary Feeding Recommendation Based on Linear Programming on Nutritional Status,Omega-3 Fatty Acids, Malondialdehyde, and Alpha-Tocopherol in Overweight Children in East Jakarta
The epidemic of pediatric obesity has become a public health burden in both developed and developing countries, due to its serious health consequences, including an increased risk of type 2 Diabetes Mellitus and heart disease.
- Conditions
- Complementary Feeding Recommendation, Linear Programming,, Nutritional Status, Omega-3 Fatty Acids
- Trial name
- NCT02592109
- Testing
- Enhanced Counseling using CFR based on Linear Programming
- Where
- Indonesia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Inflammation, Fibrosis
Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
No proven treatment exists for nonalcoholic fatty liver disease (NAFLD) in children and adolescents. We aim to determine the efficacy of lifestyle intervention with or without antioxidant therapy in pediatric NAFLD.
- Conditions
- Inflammation, Fibrosis, Insulin Resistance
- Trial name
- VITENAFLD (NCT00655018)
- Testing
- Vitamin treatment (alpha tocopherol plus ascorbic acid)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Osteoradionecrosis, Osteoradionecrosis of Jaw
Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible
Radiation is commonly used to treat cancer in the head and neck, however, this can lead to a serious complication called osteoradionecrosis (ORN), where there is necrotic (dead) open bone inside or outside of the mouth.
- Conditions
- Osteoradionecrosis, Osteoradionecrosis of Jaw, Osteoradionecrosis of the Mandible
- Trial name
- NCT06055257
- Testing
- modified PENTOCLO (mPENTOCLO)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
HIV Infections
A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs
The purpose of this study is to see if certain vitamins (C, E, B1, and B2) can keep lactate levels from becoming too high in patients who are taking nucleoside reverse transcriptase inhibitor (NRTI) anti-HIV drugs.
- Trial name
- NCT00037063
- Testing
- Thiamine hydrochloride, Riboflavin, Ascorbic acid
- Where
- 4 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)