Clinical trials: Alveolar Cleft
Cleft Lip and Palate
Liposomal Bupivacaine Use in Alveolar Bone Graft Patients
The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with…
- Trial name
- NCT06284434
- Testing
- Liposomal Bupivacaine, Bupivacain, Epinephrine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kerry O'Rourke
Alveolar Cleft
Alveolar Cleft Grafting by Double Iliac Bone Blocks Versus Iliac Spongy Bone From Anterior Iliac Crest
Reconstruction of Alveolar Cleft Using Double Iliac Corticocancellous Blocks in comparison with the gold standard technique ( cancellous bone ) both from anterior iliac crest.
- Trial name
- NCT05283005
- Testing
- Grafting of the alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Grafting
Evaluation of Computer-Guided Secondary Alveolar Cleft Bone Grafting With and Without Platelet-Rich Fibrin
This study aims at investigating the role of platelet-rich fibrin in alveolar cleft secondary grafting. This grafting is done from the patient's chin using a computer-guided stent that is customized for each patient, and the…
- Trial name
- NCT05422196
- Testing
- Platelet-rich fibrin
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cleft Lip and Palate
Fabrication of Naso-alveolar Molding (NAM) Appliance in Cleft Lip and Palate (CLP) From Digital Magnetic Resonance Imaging (MRI) Face Scan
The purpose of this study is to fabricate a nasoalveolar molding (NAM) appliance that is digitally fabricated and 3 dimensionally printed utilizing an MRI face scan and to assess the fit of the NAM in new borns with cleft lip and…
- Trial name
- NCT04369638
- Testing
- 3D NAM, Traditional NAM
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Health Science Center, Houston
Unilateral Alveolar Cleft of Maxilla
Sticky Bone Grafting With Concentrated Growth Factor Membrane for Repair of Unilateral Alveolar Cleft
The aim of this study is to evaluate using Sticky Bone grafting combined with concentrated growth factor membrane for repair of unilateral alveolar cleft.
- Trial name
- NCT07066293
- Testing
- Unilateral alveolar cleft repair
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Alveolar Cleft
Radiographic Evaluation of Secondary Alveolar Bone Grafting in Patients With Alveolar Cleft
Study about the comparison of post-operative results of secondary alveolar grafts according to two age groups: early secondary (4 to 7 years) versus late secondary (8 to 11 years) using a recently proposed score based on…
- Trial name
- SABG (NCT04845308)
- Where
- France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Montpellier
Cleft Lip and Palate, Bone Graft; Complications
Correlation Between Body Mass Index and Progressive Grafted Bone in Cleft Patients
The cleft patients received alveolar bone graft(ABG) for alveolar defect. Body mass index (BMI) was measured for each patients when receiving ABG.
- Trial name
- NCT05002920
- Testing
- alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 39 people
- Sponsor
- Chang Gung Memorial Hospital
Alveolar Cleft Grafting
Tertiary Alveolar Cleft Reconstruction Using Double Mandibular Cortical Bone Blocks Technique Versus Double Iliac Corticocancellous Bone Blocks Technique
The current study aims to compare the double mandibular corticocancellous bone blocks technique with mandibular cancellous bone particles in between versus the double iliac corticocancellous bone blocks technique with iliac…
- Trial name
- NCT07612423
- Testing
- grafting of the alveolar cleft
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cleft Lip and Palate
Tissue Engineered Constructs for Alveolar Cleft Repair
Description of the research question In children undergoing unilateral alveolar cleft reconstruction, would stem cells carried on collagen scaffold provide bone of a good quality and quantity if compared to autogenous bone…
- Trial name
- NCT03563495
- Testing
- tissue engineered group, autogenous bone graft group
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Lip and Palate
Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients
The aim of this study is to perform the bone tissue engineering to reconstruct the alveolar bone defect in cleft lip and palate patients using mesenchymal stem cells from deciduous dental pulp associated with a collagen and…
- Trial name
- NCT01932164
- Testing
- maxillary alveolar graft by tissue engineering, Bone tissue engineering using mesenchymal stem cells
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Hospital Sirio-Libanes
Cleft Lip, Congenital Nose Malformation
Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities
There is a robust body of research suggesting that the use of pre-surgical orthopedic devices prior to definitive cleft lip/nose repair results in significant improvement of facial aesthetics with long term follow up.
- Conditions
- Cleft Lip, Congenital Nose Malformation, Deformity, Nose Deformities, Acquired
- Trial name
- NCT04334590
- Testing
- Cleft Lip/Nose Repair without PSIO, Presurgical Infant Orthopedic Therapy
- Where
- United States
- Sponsor
- Johns Hopkins University
Cleft Lip Palate
Safety and Efficacy of Bone Bioengineering Kit With Stem Cells for Alveolar Cleft Repair
The objective of this study is to compare the safety and efficacy of a bone tissue engineering kit - composed of 10⁶ autologous mesenchymal stem cells derived from deciduous dental pulp combined with Bio-Oss® Collagen - with…
- Trial name
- NCT07305623
- Testing
- Bioengineering kit composed of stem cells from deciduous teeth and biomaterial., iliac crest bone graft surgery
- Where
- 2 sites in Brazil
- Volunteers
- 205 people
- Sponsor
- Instituto de Tecnologia do Paraná
Alveolar Bone Grafting, Alveolar Cleft Grafting
Serum Ropivacaine Concentrations in Pediatric Patients Receiving Continuous Wound Catheter Analgesia
The primary investigators in this study plan to investigate serum concentrations of ropivacaine in pediatric patients who already receive as standard of care a continuous wound catheter after an iliac crest alveolar bone graft…
- Trial name
- NCT02526563
- Testing
- ropivicaine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Pittsburgh
Cleft Lip and Palate
Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study
The literature on the effects of various devices on per-operative anxiety is scarce. There is currently no study on the effects of an interactive storyteller on per-operative anxiety in pediatric surgery.
- Trial name
- LUNII (NCT03740841)
- Testing
- Interactive story teller LUNII
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cleft of Alveolar Ridge
Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone in Alveolar Cleft Osteoplasty
Our aim was to combine regenerative techniques with bone grafting in human models to increase predictability and survival of reconstructed tissue.
- Trial name
- NCT02859025
- Testing
- anterior iliac crest graft, lateral ramus cortical bone+BFPSC+NBBM, anterior iliac crest graft+BFPSC+NBBM
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Alveolar Cleft
Evaluation of Bilateral Alveolar Cleft Grafting With Micro Plate Stabilization Versus Conventional Grafting Technique
The aim of the study is to enhance the maxillary segments stability during graft healing using microplate fixation to be compared with conventional grafting technique regarding gained bone quality and quantity.
- Trial name
- NCT06523855
- Testing
- bilateral alveolar cleft grafting using iliac crest particulate and microplate fixation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Alveolar Cleft
Xenografts With Platelet-rich Fibrin Versus Autogenous Bone in Alveolar Cleft Grafting
this work aims to evaluate xenografts mixed with PRF versus autogenous bone graft in alveolar cleft grafting.
- Trial name
- NCT04693741
- Testing
- secondary alveolar bone graft, Harvesting of the autogenous bone graft, Preparation of PRP
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Assiut University
Alveolar Bone Grafting, Quality of Life
Effect of Alveolar Bone Grafting
This study included patients who underwent secondary alveolar bone grafting by harvesting graft from the anterior iliac crest, in Oral and Maxillofacial Department, Faculty of Dentistry, Ankara University, Turkey, during the…
- Trial name
- NCT03549039
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ankara University
Unilateral Cleft Lip
The Effect of Use of Dermal Fat Graft as a Barrier Membrane
a study conducted to assess the use of dermal fat graft use as barrier membrane over grafted bone
- Trial name
- NCT05334602
- Testing
- Addition of dermal fat graft as protection over bone graft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Cleft
Diagnostic Efficiency of Low-dose Cone-beam Computed Tomography in Post-graft Evaluation.
Evaluation of a Low-dose exposure CBCT protocol for post-graft evaluation of treatment of cleft patients
- Trial name
- NCT06395077
- Testing
- CBCT low-dose protocol
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Malmö University