Clinical trials: Anatomical Pathological Condition
Splenomegaly, Hepatomegaly
Biomarker for Gaucher Disease: BioGaucher (BioGaucher)
Development of a new mass spectrometry-based biomarker for the early and sensitive diagnosis of Gaucher Disease from blood (plasma)
- Trial name
- BioGaucher (NCT01331642)
- Where
- 4 sites in Germany, India and 1 more
- Sponsor
- CENTOGENE GmbH Rostock
Stone, Kidney, Child, Only
Shock Wave Lithotripsy Using Fluoroscopic Versus Ultrasonic Localization
Epidemiological studies have shown a progressive increase in the incidence of pediatric urolithiasis over the past few decades.
- Trial name
- NCT05413603
- Testing
- ultrasonic focus Shock wave lithotripsy, fluoroscopic focus Shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Egymedicalpedia
Sarcopenia
Whole-body Electromyostimulation in Inpatient Rehabilitation
Based on various studies, scientific evidence has proven the effectiveness of whole-body electromyostimulation (WB-EMS) on parameters such as increased physiological performance and body composition.
- Trial name
- GERKO (NCT03767088)
- Testing
- WB-EMS, (synchronized) Training program without WB-EMS
- Where
- Germany
- Volunteers
- 134 people
- Sponsor
- Prof. Dr. Frank Mooren
Total Parenteral Nutrition-induced Cholestasis, Cholestasis
Compassionate Use of Omegaven in Children
This is a single-assignment study to evaluate whether Omegaven (IV fish oil) is effective at treating liver disease in children on long-term IV nutrition.
- Conditions
- Total Parenteral Nutrition-induced Cholestasis, Cholestasis, Short Bowel Syndrome, Gastroschisis
- Trial name
- NCT02370251
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Oklahoma
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colon Cancer
Specific Training After Stoma Surgery
In Sweden, approximately 43,000 people have undergone surgery with ileo-, colo- or urostomy. The most common type of stomy is a sigmoidostomy.
- Trial name
- STASS (NCT04701853)
- Testing
- Specific abdominal muscle training, Usual care
- Where
- 4 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Göteborg University
Pain, Inguinal Hernia
Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair
The purpose of this research study is to find the best way to decrease pain in children right after surgery whom have had their hernia fixed.
- Trial name
- NCT01740193
- Testing
- TAP Block, Ilioinguinal/iliohypogastric blockade
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Congenital Diaphragmatic Hernia, Persistent Pulmonary Hypertension of the Newborn
Milrinone in Congenital Diaphragmatic Hernia
Infants with congenital diaphragmatic hernia (CDH) usually have pulmonary hypoplasia and persistent pulmonary hypertension of the newborn (PPHN) leading to hypoxemic respiratory failure (HRF).
- Conditions
- Congenital Diaphragmatic Hernia, Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure, Pulmonary Hypoplasia
- Trial name
- NCT02951130
- Testing
- Milrinone
- Where
- 19 sites in United States
- Volunteers
- 66 people
- Sponsor
- NICHD Neonatal Research Network
Cachexia; Cancer, Muscle Wasting
Muscle Wasting in Children and Adolescents With Cancer
The series of the 3-year study aims to explore parents' experience of caring for a child's weight change among parents of children and adolescents with cancer, examine the associations and trends among muscle wasting and…
- Conditions
- Cachexia; Cancer, Muscle Wasting, Child Development, Adolescent Development
- Trial name
- NCT04353063
- Testing
- Multidisciplinary care with a personalized care
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- National Taiwan University Hospital
Large Renal Stone
A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy
Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in…
- Trial name
- NCT06394219
- Testing
- traditional transperitoneal laparoscopic pyelolithotomy, modified transperitoneal laparoscopic pyelolithotomy
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Mortality, Morbidity
Natural Orifice Specimen Extraction in Sigmoid Volvulus
Sigmoid resection can be performed using conventional and laparoscopic methods. There are few publications in the literature reporting specimen removal from the natural hole in patients with a diagnosis of sigmoid volvulus.
- Trial name
- NCT04740619
- Testing
- Natural Orifice Specimen Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Pelvic Organ Prolapse
The Development of De-novo Stress Urinary Incontinence After Stage II-III Pelvic Organ Prolapse Surgery
Surgery for Stage II-III Pelvic organ prolapse
- Trial name
- NCT03221725
- Testing
- sacrospinous ligament fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Coronary Artery Disease
Efficiency of AI Reporting (EAIR).
While there are features on a CCTA that are correlated with plaque vulnerability and can be reported on, this is not always done.
- Trial name
- EAIR (NCT05583968)
- Where
- United Kingdom
- Sponsor
- London North West Healthcare NHS Trust
Children, Adult, Plaque
Efficacy of Regular, Musical and Electric Toothbrushes in Plaque Removal in Children
Tooth brushing is essential for maintaining oral hygiene, especially in children, who are at a critical stage for developing lifelong oral health habits.
- Trial name
- NCT06541743
- Testing
- Regular Toothbrush, Musical toothbrush, Electric toothbrush
- Where
- Saudi Arabia
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Jouf University
Gastrointestinal Complication, Intestinal Obstruction
The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
- Conditions
- Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease
- Trial name
- NCT06072976
- Testing
- Standard of Care, Exclusive Human Milk
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Seattle Children's Hospital
Inguinal Hernia, Cryptorchidism
Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children
The purpose of this study is to compare the effects of caudal dexmedetomidine with intravenous dexmedetomidine on caudal levobupivacaine analgesia in children undergoing lower abdominal surgeries.
- Trial name
- NCT01701778
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine, sevoflurane
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yao Yusheng
Spinal Muscular Atrophy (SMA)
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
This is a global, prospective, multi-center study that is designed to assess the long-term safety and efficacy of OAV101 in patients who participated in an OAV101 clinical trial.
- Trial name
- SPECTRUM (NCT05335876)
- Testing
- onasemnogene abeparvovec
- Where
- 32 sites in United States, Australia and 17 more
- Volunteers
- 20 people
- Sponsor
- Novartis Pharmaceuticals
Stone, Kidney, Lithiasis Renal
Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades.
- Conditions
- Stone, Kidney, Lithiasis Renal, Surgery
- Trial name
- NCT03771365
- Testing
- Standard-PCNL, Mini-PCNL, SMP
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Anesthesia, Hernia, Inguinal
Comparative Study Between US Guided Erector Spinae and US Guided Cudal Epidural Block
Inguinal hernia is a common condition requiring surgical repair in the pediatric age group. The incidence of inguinal hernias is approximately 3% to 5% in term infants and 13% in infants born at less than 33 weeks of gestational…
- Trial name
- NCT07127601
- Testing
- Ultrasound guided erector spinae plain block (ESPB).
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Renal Calculi
Energy Ramping Versus Fixed Dose ESWL
This clinical trial compares two techniques of extracorporeal shock wave lithotripsy (ESWL) - energy ramping versus fixed dose - in adult patients with renal stones.
- Trial name
- NCT07334236
- Testing
- Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- mohammed Abdelhafez