Clinical trials: Anesthesia; Adverse Effect
Adverse Effect of Other General Anesthetics, Sequela
Automated Assessment of Difficult Airway With Facial Recognition Techniques
General anaesthesia mandates artificial ventilation and tracheal intubation in order to provide patients with artificial breathing.
- Trial name
- PeScho (NCT02022397)
- Where
- Switzerland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Adenotonsillar Hypertrophy
Teleconsultation vs Face-to-Face Evaluation for Perioperative Respiratory Events in Pediatric Adenotonsillectomy
The goal of this clinical trial is to assess whether preoperative anesthesia teleconsultation is at least equivalent to in-person consultation in preventing perioperative respiratory adverse events (such temporary reduction in…
- Trial name
- Teleped (NCT07175779)
- Testing
- Face-to-Face Preanesthesia Consultation, Telemedicine Preanestehsia Consultation
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Andrea Saporito
Anesthesia, Infant Development
General Anesthesia Exposure and Neurodevelopmental Outcome in Pediatrics
This study investigates the impact of different levels of anesthesia exposure on children's neurocognitive development and evaluates the concurrent validity of different methods that assess neurodevelopmental outcome.
- Conditions
- Anesthesia, Infant Development, Anesthesia; Adverse Effect
- Trial name
- GAP (NCT04604106)
- Testing
- Eyetracker, Ages & Stages questionnaire, Bayley Scale of Infant Development
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Nasal Obstruction, Nasopharyngeal Obstruction
Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy
Adenotomy, together with tonsillectomy, belongs among the most frequently performed surgical procedures in paediatric patients. These surgical procedures are associated with the second highest incidence of post-operative nausea…
- Conditions
- Nasal Obstruction, Nasopharyngeal Obstruction, Snoring, Apnea, Obstructive
- Trial name
- NCT03398044
- Testing
- Dexamethasone
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Airway Complication of Anesthesia
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
The main objective of this study was to investigate whether propofol assisted extubation could reduce the incidence of respiratory adverse events in children with tonsil adenoidectomy.
- Trial name
- NCT05769842
- Testing
- propofol, normal saline
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Children's Hospital of Fudan University
Tonsillectomy With or Without Adenoidectomy
Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy
To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy.
- Trial name
- NCT07118579
- Testing
- Remimazolam, Propofol, Ciprofol
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tongji Hospital
Children, Anaesthesia
NEonate-Children sTudy of Anaesthesia pRactice IN Europe Epidemiology of Morbidity and Mortality in Neonatal Anaesthesia
To study the 30-day morbidity and mortality after neonatal anaesthesia, and predictive factors that can be responsible for poor outcome.
- Trial name
- NECTARINE (NCT02350348)
- Where
- 10 sites in Belgium, Denmark and 7 more
- Volunteers
- 5,500 people
- Sponsor
- European Society of Anaesthesiology
Anesthesia; Adverse Effect
Factors Analysis Related to Prolonged Stay in the Pediatric Post-Anesthesia Care Unit(PACU)
The purpose of this study is to determine which factors contribute to prolonged stay of children in the PACU.
- Trial name
- PACU (NCT06396000)
- Volunteers
- 10,000 people
- Sponsor
- Saiqiang Guo
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Agitation
The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia
The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
- Trial name
- NCT01440114
- Testing
- fentanyl, NSS
- Where
- Thailand
- Volunteers
- 144 people
- Sponsor
- Prince of Songkla University
Emergence Delirium, Anesthesia; Adverse Effect
Language During Inhalational Induction
The aim of this study is to compare the impact of common (standard of care) language vs positive language used by clinicians during inhalational induction of anesthesia on anxiety and negative behaviors in children.
- Trial name
- NCT06324955
- Testing
- Standard/common language during induction, Positive language during induction
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Oxygen Deficiency, Desaturation of Blood
THRIVE Use in Pediatric Populations- Multi Site
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT04322994
- Testing
- Transnasal Humidified Rapid-Insufflation Ventilatory Echange
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sedative Adverse Reaction
Effect of Sedation on Pulmonary Aeration in Children
Pediatric sedation is an anesthesiological technique with a good safety profile, but various complications might ensure, especially from the respiratory point of view.
- Trial name
- LunSed (NCT03392012)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS San Raffaele
Pain, Postoperative, Adverse Reaction to Epidural Anesthesia
Pediatric Caudal Anesthesia Block. And Pain Control
Caudal epidural block CEB is the most commonly performed neuraxial block to provide effective pain relief and analgesia in patients undergoing infra-umbilical pediatric surgery.
- Conditions
- Pain, Postoperative, Adverse Reaction to Epidural Anesthesia, Anesthesia, Caudal
- Trial name
- CEB (NCT05581940)
- Testing
- Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
- Where
- Bahrain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Anesthesia; Adverse Effect
Does Sevoflurane Cause Genomic Damage
This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed.
- Trial name
- NCT03109119
- Testing
- Sevoflurane, Propofol
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Pediatric Spinal Anesthesia
Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation
The investigators can summarize intrathecal clonidine can potentiate bupivacaine thereby bringing about better quality and longer duration of analgesia, better sedation and better postoperative outcomes with minimal side effects.
- Trial name
- NCT01661803
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ACPM Medical College
Anesthesia, Anesthesia; Adverse Effect
EEG-guided Propofol Sedation Versus Standard Care for Oesophagogastroduodenoscopy and Colonoscopy in Children
The goal of this clinical trial is to compare electroencephalogram (EEG) guided propofol sedation versus standard care in paediatric patients aged 6-16 undergoing oesophagogastroduodenoscopy and colonoscopy.
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Emergence Delirium, Sedation Complication
- Trial name
- EPOC (NCT06225037)
- Testing
- Sedline EEG monitoring, Sedline EEG with output concealed
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- KK Women's and Children's Hospital
Brain Tumors
Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia
An optimal analgesic therapy is very important for postoperative recovery. In recent years, several studies showed that the prevalence of the moderate to severe pain after craniotomy ranged from 69 to 87% of patients.
- Trial name
- NCT04313374
- Testing
- Morphine PCA 1 mg, Morphine PCA 0,5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Fentanyl Adverse Reaction, Caudal Anesthesia
Fast Tracking Impact on Fentanyl Consumption and Parents Satisfaction
The investigators are measuring fentanyl consumption in micrograms used during anesthesia for patients on fast track congenital cardiac surgeries
- Trial name
- NCT04376541
- Testing
- Fentanyl
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Epinephrine Causing Adverse Effects in Therapeutic Use
Cardiovascular Effects of Racemic Epinephrine Pellets
The primary aim of this study was to determine if topical racemic epinephrine pellets affect heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) or mean arterial pressure (MAP) in children receiving…
- Trial name
- NCT04688346
- Testing
- HemeRX epinephrine pellets
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Washington