Clinical trials: Anesthesia; Adverse Effect
Perioperative Complication, Perioperative/Postoperative Complications
Registry of Anesthesia and Perioperative Medicine
To assess mortality and morbidity associated to anesthesia interventions
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Anesthesia Morbidity, Anesthesia; Adverse Effect
- Trial name
- RAMP (NCT05869578)
- Testing
- Anesthesia Intervention
- Where
- Chile
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Adenotonsillar Hypertrophy
Teleconsultation vs Face-to-Face Evaluation for Perioperative Respiratory Events in Pediatric Adenotonsillectomy
The goal of this clinical trial is to assess whether preoperative anesthesia teleconsultation is at least equivalent to in-person consultation in preventing perioperative respiratory adverse events (such temporary reduction in…
- Trial name
- Teleped (NCT07175779)
- Testing
- Face-to-Face Preanesthesia Consultation, Telemedicine Preanestehsia Consultation
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Andrea Saporito
Adverse Effect of Other General Anesthetics, Sequela
Automated Assessment of Difficult Airway With Facial Recognition Techniques
General anaesthesia mandates artificial ventilation and tracheal intubation in order to provide patients with artificial breathing.
- Trial name
- PeScho (NCT02022397)
- Where
- Switzerland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Anesthesia; Adverse Effect, Congenital Heart Disease
The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes to the wide variation in neurologic…
- Conditions
- Anesthesia; Adverse Effect, Congenital Heart Disease, Neurodevelopmental Disorders
- Trial name
- NDO (NCT03882788)
- Testing
- Isoflurane, Fentanyl (high dose), Fentanyl (low dose)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Stanford University
Postoperative Pain
Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects
Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now.
- Trial name
- NCT03058354
- Testing
- Propofol, general anaesthesia
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Anesthesia; Adverse Effect
Does Sevoflurane Cause Genomic Damage
This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed.
- Trial name
- NCT03109119
- Testing
- Sevoflurane, Propofol
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Anesthesia, Conduction, Nerve Block
Neurologic Complications in Peripheral Regional Anesthesia - An Evaluation Based on a Standardized Protocol
To evaluate the incidence of neurologic complications as a consequence of peripheral regional anesthesia, all patients receiving peripheral nerve blocks will be evaluated according to a standardized protocol screening pain…
- Conditions
- Anesthesia, Conduction, Nerve Block, Adverse Effects
- Trial name
- NCT00445016
- Testing
- peripheral regional anesthesia
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- BG Unfallklinik Murnau
Oxygen Deficiency, Desaturation of Blood
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT03430206
- Testing
- High-flow nasal cannula
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Stanford University
Evaluation of Success Rate, Airway Leak Pressure
Evaluation of Supraglottic Airway Devices in Children and Comparison to Historic Control
The supraglottic airway device LMA Supreme has recently been introduced for pediatric patients. The investigators will prospectively evaluate success rate and airway leak pressure in everyday's clinical pediatric anesthesia…
- Conditions
- Evaluation of Success Rate, Airway Leak Pressure, Side Effects of LMA Supreme in Pediatric Patients Undergoing General Anesthesia
- Trial name
- NCT01625858
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia, Infant Development
General Anesthesia Exposure and Neurodevelopmental Outcome in Pediatrics
This study investigates the impact of different levels of anesthesia exposure on children's neurocognitive development and evaluates the concurrent validity of different methods that assess neurodevelopmental outcome.
- Conditions
- Anesthesia, Infant Development, Anesthesia; Adverse Effect
- Trial name
- GAP (NCT04604106)
- Testing
- Eyetracker, Ages & Stages questionnaire, Bayley Scale of Infant Development
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Multiparametric Magnetic Resonance Imaging, Propofol Adverse Reaction
Safety Evaluation of Propofol Sedation for Magnetic Resonance Imaging in Pediatric Patients
Propofol is often used for sedation in children undergoing magnetic resonance imaging. The investigators will perform a chart review of 4 month of activity (about 100 cases) and review the incidence and severity of adverse events…
- Conditions
- Multiparametric Magnetic Resonance Imaging, Propofol Adverse Reaction, Sedation Complication, Anesthesia; Adverse Effect
- Trial name
- NCT04455776
- Testing
- Propofol
- Where
- Belgium
- Volunteers
- 99 people
- Sponsor
- Brugmann University Hospital
Anesthesia, Airway Complication of Anesthesia
Apnoeic Oxygenation During Pediatric Tracheal Intubation
The goal of this randomized, controlled, single-blinded clinical trial is to evaluate the effectiveness of apnoeic Oxygenation in pediatric anesthesia.
- Conditions
- Anesthesia, Airway Complication of Anesthesia, Anesthesia; Adverse Effect
- Trial name
- NCT06576596
- Testing
- apnoeic Oxygenation
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Heidelberg
Pediatric Spinal Anesthesia
Intrathecal Bupivacaine Versus Bupivacaine and Clonidine in Paediatrics Age Group:A Comparative Evaluation
The investigators can summarize intrathecal clonidine can potentiate bupivacaine thereby bringing about better quality and longer duration of analgesia, better sedation and better postoperative outcomes with minimal side effects.
- Trial name
- NCT01661803
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ACPM Medical College
Sleep Apnea, Obstructive, Tonsillectomy
The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
This is a research study using caffeine in children who have an obstructive sleep apnea (OSA). OSA means children who stop breathing during their sleep due to obstruction in their airway.
- Conditions
- Sleep Apnea, Obstructive, Tonsillectomy, Adenoidectomy, Postoperative Complications
- Trial name
- OSA (NCT00273754)
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center, Houston
Children, Anaesthesia
NEonate-Children sTudy of Anaesthesia pRactice IN Europe Epidemiology of Morbidity and Mortality in Neonatal Anaesthesia
To study the 30-day morbidity and mortality after neonatal anaesthesia, and predictive factors that can be responsible for poor outcome.
- Trial name
- NECTARINE (NCT02350348)
- Where
- 10 sites in Belgium, Denmark and 7 more
- Volunteers
- 5,500 people
- Sponsor
- European Society of Anaesthesiology
Sedative Adverse Reaction
Effect of Sedation on Pulmonary Aeration in Children
Pediatric sedation is an anesthesiological technique with a good safety profile, but various complications might ensure, especially from the respiratory point of view.
- Trial name
- LunSed (NCT03392012)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS San Raffaele
Fentanyl Adverse Reaction, Caudal Anesthesia
Fast Tracking Impact on Fentanyl Consumption and Parents Satisfaction
The investigators are measuring fentanyl consumption in micrograms used during anesthesia for patients on fast track congenital cardiac surgeries
- Trial name
- NCT04376541
- Testing
- Fentanyl
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Oxygen Toxicity, Anesthesia; Adverse Effect
Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia
The goal of this RCT is to demonstrate that, in neonatal anesthesia, the use of Lung Ultrasound (LUS) to guide choice of best Positive End-Expiratory Pressure (Peep) - the one that efficiently avoids lung atelectasis - leads to…
- Trial name
- NCT05737407
- Testing
- LUS-guided choice of Peep, Standard choice of Peep
- Where
- Italy
- Volunteers
- 280 people
- Sponsor
- Vittore Buzzi Children's Hospital
Anesthesia, Anesthesia; Adverse Effect
EEG-guided Propofol Sedation Versus Standard Care for Oesophagogastroduodenoscopy and Colonoscopy in Children
The goal of this clinical trial is to compare electroencephalogram (EEG) guided propofol sedation versus standard care in paediatric patients aged 6-16 undergoing oesophagogastroduodenoscopy and colonoscopy.
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Emergence Delirium, Sedation Complication
- Trial name
- EPOC (NCT06225037)
- Testing
- Sedline EEG monitoring, Sedline EEG with output concealed
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- KK Women's and Children's Hospital
Infection, Inflammation
Complications and Adverse Effects in Continuous Peripheral Regional Anesthesia
The investigators prospectively document infectious, neurological, and other complications or adverse events occurring during peripheral regional anesthesia via a catheter using computer-based data recording.
- Conditions
- Infection, Inflammation, Adverse Effects
- Trial name
- NCT00251654
- Testing
- perineural block (anesthesia)
- Where
- Germany
- Volunteers
- 9,000 people
- Sponsor
- Rechbergklinik Bretten