Clinical trials: Aneurysm, Brain
Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease
Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit
The wireless NIRS sensor will be placed on the participant's forehead, directly underneath the INVOS wired sensor. The wireless NIRS sensor will remain in place for 4 consecutive hours, over 2 consecutive days.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease, Stroke Hemorrhagic, Aneurysm Cerebral
- Trial name
- NCT07732244
- Testing
- Wireless NIRS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Brain Aneurysm
Aneurysm Study of Pipeline in an Observational Registry
The primary objective of this study is to further expand the body of clinical knowledge in patients undergoing Pipeline Embolization Device (Pipeline or PED) placement for intracranial aneurysms (IAs or ICAs) according to…
- Trial name
- ASPIRE (NCT01557036)
- Testing
- Pipeline Embolization Device
- Where
- 36 sites in United States, Argentina and 6 more
- Volunteers
- 200 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
Stroke, Thromboses, Intracranial
Stroke Thrombectomy and Aneurysm Registry
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the…
- Conditions
- Stroke, Thromboses, Intracranial, Aneurysm, Brain
- Trial name
- STAR (NCT04994756)
- Testing
- Stroke/Thrombectomy/Aneurysm-specific surgical procedures
- Where
- 63 sites in United States, Canada and 7 more
- Volunteers
- 40,000 people
- Sponsor
- Medical University of South Carolina
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion
Brain Aneurysm, Stroke
Safety and Efficacy of Aneurysms Treated With Endovascular Devices
In this project the investigators study the safety and efficacy of the recent endovascular devices used in treatment of brain aneurysms.
- Conditions
- Brain Aneurysm, Stroke, Intracranial Hemorrhages
- Trial name
- SEATED (NCT07175519)
- Testing
- Endovascular treatment of aneurysms
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- King's College London
Arteriovenous Malformations, Cerebral, Unruptured Brain Arteriovenous Malformation
Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations
A new endovascular route for the treatment of brain AVMs may be possible in some cases: Trans-Venous Embolization (TVE). The technique uses microcatheters to navigate to the draining veins of AVM, to reach and then fill the AVM…
- Conditions
- Arteriovenous Malformations, Cerebral, Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation
- Trial name
- TATAM (NCT03691870)
- Testing
- Standard Trans-Arterial Embolization (TAE), Trans-Venous Embolization (TVE)
- Where
- 9 sites in Canada, France
- Volunteers
- 77 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Brain Aneurysms
International Retrospective Study of Pipeline Embolization Device
The primary objective of this retrospective study is to determine the incidence of important safety outcomes in patients who have undergone Pipeline Embolization Device placement for intracranial aneurysms (IAs).
- Trial name
- IntrePED (NCT01558102)
- Where
- 17 sites in United States, Argentina and 4 more
- Volunteers
- 793 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation
Treatment of Brain AVMs (TOBAS) Study
The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of…
- Conditions
- Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation, Arteriovenous Malformations, AVM
- Trial name
- TOBAS (NCT02098252)
- Testing
- Neurosurgery, Radiation therapy, Embolization
- Where
- 30 sites in United States, Brazil and 4 more
- Volunteers
- 1,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Aneurysm, Aneurysm, Brain
Setting Benchmarks for Microsurgical Clipping of Unruptured Intracranial Aneurysms
To conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following microsurgical clipping of unruptured intracranial aneurysms (UIA).
- Conditions
- Aneurysm, Aneurysm, Brain, Aneurysm Cerebral, Aneurysm of Cerebral Artery
- Trial name
- NCT05029947
- Testing
- Microsurgical Clipping of Unruptured Intracranial Aneurysm
- Where
- Germany
- Volunteers
- 3,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Subarachnoid Hemorrhage, Brain Ischemia
Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
Dapsone is a drug that has been used clinically for several decades due to its anti-infective effect, making it widely available. Its neuroprotective effects have been found through its glutamate receptors antagonistic effect.
- Conditions
- Subarachnoid Hemorrhage, Brain Ischemia, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- NCT05131295
- Testing
- Dapsone, Aluminum Hydroxide Gel
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Epileptic Seizure, Intracranial Tumor
Our Anesthesia Experience During MRI Scan
In this study we aim to investigate the relationship between our anesthesia practice and post procedure complications after MRI scanning with sedation. This is a retrospective, single center observational study.
- Conditions
- Epileptic Seizure, Intracranial Tumor, Intracranial Hypertension, Intracranial Aneurysm
- Trial name
- NCT03123302
- Where
- Turkey (Türkiye)
- Volunteers
- 977 people
- Sponsor
- Akdeniz University
Brain Aneurysm
Current Treatment Modalities for Wide Necked Intracranial Aneurysms
Give an effective treatment for intracranial wide necked aneurysm and can detect the best method could be used. Improve the outcome of these patients and decease rate of recurrence and complications.
- Trial name
- NCT03852680
- Testing
- aneurysm clipping
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intracranial Aneurysm, Brain Edema
Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
This is a prospective, randomized controlled trial to determine if using FloTrac/EV1000 system in neurosurgical patients undergoing craniotomies for aneurysm repair or tumor resection complicated by cerebral edema, or complex…
- Conditions
- Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
- Trial name
- NCT02701582
- Testing
- Phenylephrine, Epinephrine, Albumin
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- NYU Langone Health
Arteriovenous Malformations, Cavernous Angiomas
Influence of MMP on Brain AVM Hemorrhage
Brain vascular malformations, including arteriovenous malformations (AVM), cavernous malformations (CVM) and aneurysms, are a source of life-threatening risk of intracranial hemorrhage. The etiology and pathogenesis are unknown.
- Conditions
- Arteriovenous Malformations, Cavernous Angiomas, Brain Aneurysms
- Trial name
- NCT00783523
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of California, San Francisco