Clinical trials: Anginal Pain
Coronary Artery Disease, Angina Pectoris
SORT-OUT VI - Randomized Clinical Comparison of Biomatrix Flex® and Resolute Integrity®
To perform a randomized comparison between the BioMatrix Flex™ and the Resolute Integrity® stents in the treatment of unselected patients with ischemic heart disease.
- Trial name
- SO VI (NCT01956448)
- Testing
- Drug eluting stent
- Where
- 3 sites in Denmark
- Volunteers
- 2,800 people
- Sponsor
- Aarhus University Hospital Skejby
Cardiovascular Disease
High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi…
- Trial name
- NCT01306565
- Testing
- Low dose Atorvastatin, High dose atorvastatin
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Healthy
Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets
This study will determine whether and how nitrites and nitrates in the diet affect the level of nitric oxide gas that is breathed out in air.
- Trial name
- NCT00027157
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Heart Disease, Angina Pectoris
The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris
The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.
- Trial name
- NCT00737958
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Coronary Disease, Myocardial Ischemia
Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease
This study will test whether inhaling nitric oxide gas can improve blood flow to the heart, ventricular function, exercise tolerance in patients with coronary artery disease and chest pain that has not improved with medical or…
- Trial name
- NCT00014040
- Testing
- Nitric Oxide and INOpulse Delivery System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital
Angina Pectoris, Cardiovascular Diseases
Women's Ischemia Syndrome Evaluation (WISE)
To evaluate innovative diagnostic methods that will improve the diagnostic reliability of cardiovascular testing in evaluation of ischemic heart disease in women.
- Conditions
- Angina Pectoris, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000554
- Testing
- Angiography, MRI, Dobutamine-Stress Echocardiography, PET,, Myocardial Contrast Echo, Coronary Flow and Vasomotor Testing
- Sponsor
- University of Pittsburgh
Angina
Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief
Nasal oxygen is widely used as pain relief against ischemic pain during Percutaneous Coronary Intervention (PCI). However, to our knowledge no randomised clinical trials have tested this.
- Trial name
- OXYPAIN (NCT01413841)
- Testing
- Nasal oxygen, Regular nasal air
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Angina Pectoris, Coronary Heart Disease
Reducing the Pro-ischaemic Effects of Air Pollution Exposure Using a Simple Face Mask
Air pollution is a major cause of cardiorespiratory morbidity and mortality. The exact components of air pollution that underlie the cardiovascular effects are not yet known, but combustion-derived particulate matter is suspected…
- Conditions
- Angina Pectoris, Coronary Heart Disease, Blood Pressure, Heart Rate Variability
- Trial name
- NCT00809653
- Testing
- No Face Mask, Face Mask
- Where
- China
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Acute Myocardial Infarction, Unstable Angina
Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study
The EMERALD II study is a multinational, multicenter, and retrospective study. ACS patients who underwent CCTA from 1 months to 3 years prior to the event will be retrospectively identified.
- Trial name
- EMERALD II (NCT03591328)
- Testing
- Coronary CT angiography
- Where
- South Korea
- Volunteers
- 429 people
- Sponsor
- Seoul National University Hospital
Vasospastic Angina
Immunomodulatory Therapy & VSA
Vasospastic angina (VSA) is caused by brief spasms of the main coronary artery and its major branches, resulting in varying degrees of luminal occlusion.
- Trial name
- NCT06696807
- Testing
- glucocorticosteroids and/or intravenous immunoglobulin
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Dao Wen Wang
Coronary Heart Disease, Angina Pectoris
Safety Study of DanshenDuofensuanyan(a Chinese Medicine Injection)Used in Hospitals in China
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in January 2013.
- Trial name
- NCT01814566
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Stable Angina Pectoris
Prevalence and Prognostic Value of Unrecognized Myocardial Injury in Stable Coronary Artery Disease (PUMI)
This study includes patients with stable coronary artery disease without previously known myocardial infarction, and investigates the prevalence of clinically unrecognized myocardial damage and its prognostic implication.
- Trial name
- PUMI (NCT01257282)
- Where
- 6 sites in Sweden
- Volunteers
- 275 people
- Sponsor
- Uppsala University
Angina Pectoris, Variant
Efficacy Study of Atorvastatin to Treat Variant Angina
The objective of this study is to evaluate effect of statin treatment for vasospastic angina.
- Trial name
- ESAVA (NCT00620204)
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Samsung Medical Center
Stable Angina, Unstable Angina, Silent Coronary Ischemia, Coronary Artery Disease
ISAR-DAPT (A Comparative Evaluation of Efficacy and Safety in the 3-Months DAPT Group vs. the 6-Months DAPT Group of Patients Treated With the Coroflex ISAR Stent; A Prospective, Multicenter, Randomized, Open-Label Clinical Trial)
This clinical trial studies patients treated with the Coroflex ISAR Stent for coronary artery disease in order for the objective of verifying the non-inferiority of results that among patients who were administered DAPT for 3…
- Trial name
- NCT02609698
- Testing
- Coroflex ISAR, 3 months DAPT, 6 months DAPT
- Where
- South Korea
- Volunteers
- 906 people
- Sponsor
- Ajou University School of Medicine
Angina
The Syndrome X-ercise Study SYNDEX
This pilot study evaluates the effect of exercise training on CFR, functional capacity, heart rate variability, endothelial function and quality of life in patients with no obstructive coronary artery disease and angina.
- Trial name
- SYNDEX (NCT02905630)
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Helse Stavanger HF
Angina, Status Post PCI
Impact of Coronary Anatomy on Angina Relief in Patients Undergoing Coronary Revascularization
We hypothesize that Coronary Artery Disease (CAD) severity assessed by SYNTAX score is an independent predictor of recurrent or persistent angina following coronary revascularization.
- Conditions
- Angina, Status Post PCI, Status Post CABG
- Trial name
- NCT01665833
- Volunteers
- 4,000,000 people
- Sponsor
- North Texas Veterans Healthcare System
Congestive Heart Failure, Angina
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Heart Disease
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of congestive heart failure and angina
- Trial name
- NCT05147766
- Testing
- AlloRx
- Where
- 2 sites in Antigua and Barbuda, Argentina
- Volunteers
- 3 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Angina Pectoris, Microvascular Angina
Angina in Non Coronary Artery Disease
Many patients undergoing coronary angiography are found to have no significant coronary artery disease (CAD) despite angina equivalent symptoms and/or electrocardiographic abnormalities suggestive of myocardial ischemia.
- Conditions
- Angina Pectoris, Microvascular Angina, Angina Pectoris, Variant
- Trial name
- HeartQuest (NCT01318629)
- Where
- Switzerland
- Volunteers
- 718 people
- Sponsor
- Luzerner Kantonsspital
Heart Diseases, Cardiovascular Diseases
Acute Cardiac Ischemia in Women in the ACI/TIPI Trial
To conduct a series of five inter-related studies on acute cardiac ischemia (ACI) in women.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Angina Pectoris, Myocardial Ischemia
- Trial name
- NCT00005701
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)