Clinical trials: Ankle Sprains
Ankle Sprains
Comparison Between Two Mobilization Techniques of Ankle on Balance in Patients With Chronic Ankle Instability
The ankle joint is often affected by injuries, especially lateral sprains, often leading to chronic instability. Joint mobilization techniques seem to influence the sense of joint positioning.
- Trial name
- NCT03079804
- Testing
- Experimental MWM, Experimental Thrust
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal do Ceara
Ankle Sprain
FS-67 in the Treatment of Pediatric Patients With Ankle Sprain
The objective of this study is assess the efficacy and safety of single and multiple applications of the FS-67 patch in the treatment of ankle sprain in pediatric population (ages 13-17).
- Trial name
- NCT01037816
- Testing
- FS-67 Patch
- Where
- 23 sites in United States
- Volunteers
- 252 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Physical Therapy
Impact of Physiotherapy Intervention for Children With Ankle Sprains
This study will investigate whether adding a physiotherapy intervention to standard Emergency Department care will lead to improved recovery following an ankle sprain in the pediatric and adolescent population as well as to a…
- Trial name
- NCT01405274
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Ankle Sprains
A Mobile Recovery Guidance App for Children and Young Adults With Acute Ankle Inversion Injuries
Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a…
- Trial name
- SPRAIN (NCT05785533)
- Testing
- Smartphone App, Standard of Care
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Naveen Poonai
Ankle Sprains
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains
A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle…
- Trial name
- NCT01198834
- Testing
- MRX-7EAT, Lidocaine, Etodolac
- Where
- 33 sites in United States
- Volunteers
- 600 people
- Sponsor
- MEDRx USA, Inc.
Ankle Sprains, Telerehabilitation
Telehealth Delivered Physical Rehabilitation for an Ankle Sprain
A vast majority (75-85%) of ankle sprain patients treated in emergency departments (ED) receive pain medication and are not referred for physical rehabilitation.
- Conditions
- Ankle Sprains, Telerehabilitation, Analgesic, Opioid, Analgesics, Non-narcotic
- Trial name
- NCT04520854
- Testing
- Telehealth Protocol, Usual Care
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kyle Kosik
Acute Ankle Sprain
Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain
This is a randomized, multi-center, double-blind, placebo-controlled, multi-dose, parallel-group study. Approximately 300 subjects (150 per group) 16 years of age and older with a current (within 24 hours from Visit 1) Grade I or…
- Trial name
- NCT01874626
- Testing
- SST-0225 Topical Ibuprofen Cream
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Strategic Science & Technologies, LLC
Sprains and Strains
Ankle Manual Therapy for Ankle Sprains
The purpose of this study is to determine the effect of using ankle manual therapy procedures on clinical outcomes in individuals with post-acute ankle sprains.
- Trial name
- AMT (NCT00888498)
- Testing
- Passive Positioning, High-Velocity, Low-Amplitude Stretch, Slow, Mobilization Stretch
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of the Pacific
Ibuprofen, Ankle Injuries
Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children
Ankle sprains are common in children, and optimal pain management has not been determined. We hypothesize that children age 7-17 years of age with acute ankle sprain randomized to receive regular dose ibuprofen will show a…
- Trial name
- NCT01092676
- Testing
- Ibuprofen Regular Dosing, PRN dosing Ibuprofen
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Ankle Sprains
Smartphone App to Improve Functional Outcomes in Ankle Sprains
Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a…
- Trial name
- SPRAIN (NCT03564015)
- Testing
- Smartphone app, Paper handout
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ankle Sprain
Systematic Ultrasound in the Initial Assessment of Ankle Sprain
Ankle sprains are the most frequently encountered trauma in emergency and general medicine. Lateral ankle sprain injuries have the highest relapse rate of all musculoskeletal injuries of the lower limbs.
- Trial name
- PFEEC (NCT06856889)
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Hopital Nord Franche-Comte
Pain in Leg, Unspecified, Knee Sprain
Efficacy of Instrumental Chiropractic Treatment Using Activator Methods for Pain and Dysfunction in Juvenile Athletes
The goal of the study is to prove efficacy of instrumental chiropractic treatment for leg pain in juvenile athletes. A randomized placebo controlled clinical trial including juvenile athletes with functional impairment and pain…
- Trial name
- NCT01449994
- Testing
- Activator IV (Activator Methods Int. Phoenix, Arizona)
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Sprain of Ankle
Evaluation of the Effect of the Association of Proton Pump Inhibitor (PPIs) With Non-Steriodal Anti-Inflamatories (NSAIDs) in Work Leave Time.
Retrospective cohort study to evaluate the effect of the association of PPIs with NSAIDs in work leave time.
- Trial name
- NCT00717119
- Where
- Spain
- Volunteers
- 6,356 people
- Sponsor
- AstraZeneca
Ankle Sprain
A Comparison of Early Mobilization Versus Traditional Treatment for Acute Ankle Sprains.
Acute ankle sprain is one of the most common musculoskeletal injuries, accounting for an estimated 2 million injuries per year and 20% of all sports injuries in the United States.
- Trial name
- NCT01134653
- Testing
- Jump Stretch
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Nationwide Children's Hospital
Ankle Sprain 1St Degree
First-degree Ankle Sprains
Grade I ankle sprains are common, especially among athletes, women, teenagers, and physically active individuals. While over a million cases are reported annually, this represents only half of the total occurrences.
- Trial name
- NCT06645262
- Testing
- Cryotherapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- Rehabilitation Centre Zivot
Ankle Injuries, Ligament Injury
Medial and Lateral Combined Ligament Arthroscopic Repair for Multidirectional Ankle Instability: Case Series
Abstract Introduction: The high prevalence of sprains in the population has provided a substantial number of patients with lateral instability of the ankle.
- Conditions
- Ankle Injuries, Ligament Injury, Joint Instability, Deltoid Ligament; Sprain (Strain) (Ankle)
- Trial name
- NCT04459910
- Testing
- Arthroscopic Brostrom combined with Arthroscopic Deltoid Repair
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- Federal University of São Paulo
Ankle Injuries
5% Topical Ibuprofen (IBU) for Ankle Sprain
This study is being conducted to evaluate the effects of IBU 5% Topical Gel versus topical placebo for the relief of pain associated with a first or second degree ankle sprain.
- Trial name
- NCT01945034
- Testing
- Topical IBU twice daily, Topical IBU three times daily
- Where
- 19 sites in United States
- Volunteers
- 304 people
- Sponsor
- Pfizer
Ankle Injuries
Effects of Proprioceptive Training on Neurofunctional Control and Ankle Sprains Incidence
The aim of this study is to investigate the influence of a 12-week proprioceptive training program on the neurofunctional control and the incidence of ankle sprains in fencing athletes.
- Trial name
- NCT02739308
- Testing
- Proprioceptive Training, Control Group
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of Rio Grande do Sul
Young Football Players, Ankle Sprain Prevention
Comparison Interventions on Kinetic and Kinematic Parameters
Currently, it is difficult to find studies in the literature comparing proprioception exercises with the effect of manual therapy on improving balance, and in the long run it may translate into improved activity, functionality…
- Trial name
- Balance (NCT07326475)
- Testing
- Manual therapy, Exercise
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk