Clinical trials: Apathy
Parkinson Disease, Apathy
Move to Improve Physical Activity in Parkinson's Disease
Apathy is a multi-dimensional behavior characterized by impairments to motivation, planning and initiation; collectively called, goal-directed behavior.
- Trial name
- MoTIvatE (NCT04051151)
- Testing
- Gameficiation
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Pennsylvania
Apathy, Alzheimer's Disease
Apathy in Dementia Methylphenidate Trial 2
Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a Phase III, placebo-controlled, masked, 6 month, multi-center randomized clinical trial sponsored by National Institutes of Aging involving 200 participants with…
- Trial name
- ADMET2 (NCT02346201)
- Testing
- Methylphenidate
- Where
- 10 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Alzheimer Disease, Apathy in Dementia
rTMS for Apathy Clinical Trial
Apathy is a common, early, and disabling symptom in dementias and mild behavioural impairment such as Alzheimer's disease (AD) and is characterized by lack of interest and enthusiasm.
- Conditions
- Alzheimer Disease, Apathy in Dementia, Dementia, Mild Behavioural Impairment
- Trial name
- REACT (NCT05561205)
- Testing
- rTMS, methylphenidate
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Lack of; Attention, With Hyperactivity (ADHD)
Treatment Plan for ADHD With Indifferent Traits
For children with ADHD aged 4-10 at the time of enrollment, starting from preschool, focusing on apathy and emotional control, using psycho-behavioral measurements, EEG experiments, and eye tracking technology to evaluate and…
- Trial name
- NCT05075447
- Testing
- Emotion Control Treatment Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Emotions, Dementia
Dementia Associated Apathy.
We want to determine if patients with dementia show any kind of emotion while they look at a defined selection of photos. These are photos taken from a international image-platform and mixed with photos (biographic) that show…
- Conditions
- Emotions, Dementia, Apathy
- Trial name
- NCT03293537
- Testing
- Skin conductance and Heart rate measurement
- Where
- Switzerland
- Volunteers
- 133 people
- Sponsor
- Zurich University of Applied Sciences
Tourette Syndrome, Apathy
Apathy in Tourette Syndrome and Changes in Quality of Life
Tourette syndrome is a complex neuropsychological disorder with both motor and vocal tics associated with multiple psychological co-morbidities. Apathy has not been widely studied in patients with Tourette syndrome.
- Trial name
- NCT02765178
- Testing
- Children's Motivation Scale, Yale Global Tic Severity Scale (YGTSS), Studies Depression Scale for Children (CES-DC)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Florida
Parkinson's Disease, Deep Brain Stimulation
Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease
The primary objective of the study is to determine if subthalamic nucleus (STN) deep brain stimulation (DBS) using the Vercise directional leads improves neuropsychiatric state and neuropsychiatric fluctuations 12 months after…
- Trial name
- Steeropt (NCT04578678)
- Testing
- Steering
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 105 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Alzheimer s Disease, Alzheimer Dementia (AD)
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
This study evaluates whether the combined treatment of methylphenidate and non-invasive brain stimulation, called intermittent theta burst stimulation, can effectively treat apathy in individuals with Alzheimer's disease or mixed…
- Conditions
- Alzheimer s Disease, Alzheimer Dementia (AD), Alzheimer Dementia, Alzheimer Disease
- Trial name
- PRIME (NCT07279740)
- Testing
- intermittent theta burst stimulation (iTBS), Methylphenidate (MPH)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
Parkinson's Disease, Apathy
Study of Rivastigmine to Treat Parkinsonian Apathy Without Dementia
Apathy usually refers to a set of behavioural, emotional and cognitive features as a reduced interest and participation in main activities of daily life, a lack of initiative, a trend toward an early withdrawal from started…
- Conditions
- Parkinson's Disease, Apathy, no Dementia
- Trial name
- CHoPA-I (NCT00767091)
- Testing
- rivastigmine
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille