Clinical trials: Appendix
Appendix Cancer, Pseudomyxoma Peritonei
The Appendix Cancer PMP Research Foundation Natural History Study/Patient Registry
ACPMP's first-ever patient-powered global patient registry/natural history study collects patient and caregiver information and data to fuel clinical trials and drive breakthroughs for appendix cancer and PMP.
- Trial name
- NCT07769346
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Appendix Cancer Pseudomyxoma Peritonei Research Foundation
Appendicitis
Impact of Oral Contrast in the Large Intestine on the Recognition of Appendix
Acute appendicitis is the most common cause of abdominal pain requiring surgical intervention. The gold standard test for the diagnosis of acute appendicitis is the CT scan.
- Trial name
- NCT02497183
- Testing
- ultrasound, iodine based solution of oral contrast material
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- HaEmek Medical Center, Israel
Appendicitis
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
- Trial name
- HASSEL (NCT07049965)
- Testing
- Suture ligation, Harmonic Scalpel
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Acute Appendicitis
IA Model for Acute Appendicitis in CT
the investigators's study group has developed a fully automated 3D convolutional neural network (CNN)-based diagnostic framework using information of appendix (IA) model to identify non-appendicitis and simple and complicated…
- Trial name
- NCT06175169
- Testing
- Information of Appendix (IA) model
- Where
- South Korea
- Volunteers
- 568 people
- Sponsor
- Hallym University Medical Center
Appendicitis
Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
Acute appendicitis (AA) is the most common condition requiring emergency surgery in children. At a network of institutions nationwide, a tool called the pediatric appendicitis risk calculator (pARC)1 is being studied to assess…
- Trial name
- NCT03522233
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Carcinoma of the Appendix, Colorectal Cancer
Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Carcinoma of the Appendix, Colorectal Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00006112
- Testing
- chemotherapy, fluorouracil, leucovorin calcium
- Where
- France
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Appendix Diseases, Surgery
Treatment Strategy for Complicated Pediatric Appendicitis Based on Laparoscopic Surgery
Observational retrospective study included 765 children with Operative management by laparoscopic appendectomy, conservative management for appendicular mass and drainage of abscess by IR should be tried first.
- Trial name
- CALAP (NCT07385261)
- Testing
- laparoscopic appendectomy
- Where
- Egypt
- Volunteers
- 765 people
- Sponsor
- Mohammad Daboos
Laparoscopic Appendectomy
Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require…
- Trial name
- NCT06945263
- Testing
- Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Acute Appendicitis, Abdominal Pain (AP)
Preserving or Resecting the Normal Appendix in Patients Undergoing Laparoscopy Surgery for Suspected Appendicitis
When appendicitis is suspected, patients are typically planned for emergency surgery preferably using a laparoscopic approach. Up to 20% of these patients will have a normal appendix, thus not suffering from appendicitis.
- Conditions
- Acute Appendicitis, Abdominal Pain (AP), Diagnostic Laparoscopy, Laparoscopic Appendectomy
- Trial name
- NCT06917612
- Testing
- Normal diagnostic laparoscopy, Negative appendectomy
- Volunteers
- 20,000 people
- Sponsor
- Herlev Hospital
Appendix, Appendectomy
Selective Rather Than Routine Histopathological Examination Following Appendectomy and Cholecystectomy
The FANCY study will investigate whether a selective policy of histopathological examination of appendices and gallbladders based on the intraoperative findings of the surgeon is safe and cost-effective.
- Conditions
- Appendix, Appendectomy, Appendiceal Neoplasms, Gallbladder
- Trial name
- FANCY (NCT03510923)
- Testing
- Inspection and palpation of the appendix, Inspection and palpation of the gallbladder
- Where
- Netherlands
- Volunteers
- 17,380 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pediatric ALL, Appendix Diseases
The Effectiveness of the Training Given With Audio and Picture Book Before the Surgery
Behavioral practices applied to the child in the preoperative period; It includes methods such as introducing the hospital and operating room to children and their parents, reading storybooks, giving training books, an…
- Trial name
- NCT04960761
- Testing
- İntervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Parasitic Disease
Enterobius Vermicularis Infestation of the Appendix
This study identifies the incidence of appendiceal Enterobius vermicularis (E.v) infestation in all the patients undergoing appendectomy and evaluates the relationship between E.v infestation of the appendix and the acute…
- Trial name
- NCT04576273
- Testing
- Pathology examination
- Where
- Saudi Arabia
- Volunteers
- 1,150 people
- Sponsor
- Al-Azhar University
Neoplasms, Appendix Cancer
Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the Appendix
The goal of this observational study is to investigate the beneficial value of complementary surgery for appendiceal neuro-endocrine tumours in children. .
- Trial name
- NETkids (NCT05919758)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cancer
Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer
RATIONALE: Hepatic arterial infusion uses a catheter to deliver anticancer substances directly into the liver. Drugs used in chemotherapy, such as melphalan, work in different ways to stop tumor cells from dividing so they stop…
- Trial name
- NCT00096083
- Testing
- isolated perfusion, melphalan
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Delcath Systems Inc.
Appendicitis, Appendix Mass
Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population
Aim of this study is to evaluate the effect of different treatment strategies on overall complications, health related-Quality of Life (hr-QOL) and costs among two subtypes of complex appendicitis in children (<18 years old).
- Conditions
- Appendicitis, Appendix Mass, Appendicitis Perforated
- Trial name
- CAPP (NCT04755179)
- Testing
- Laparoscopic appendectomy, Open appendectomy, Non-operative treatment
- Where
- 32 sites in Netherlands
- Volunteers
- 1,308 people
- Sponsor
- Ramon Gorter
Appendix Rupture, Pain
Virtual Reality for Appendectomy Pain
To determine the impact of VR-Biofeedback and VR-Distraction on pain and medication utilization in children and adolescents undergoing surgery for ruptured appendix.
- Conditions
- Appendix Rupture, Pain, Pain, Postoperative
- Trial name
- NCT04357132
- Testing
- VR-Biofeedback, VR-Distraction
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Inflammation of Appendix
Laparoscopic Versus Open Appendectomy
comparison between laparoscopic and open appendectomy in the management of chronic appendicitis
- Trial name
- NCT04618666
- Testing
- laparoscopic and open surgery intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Advanced Malignant Mesothelioma, Carcinoma of the Appendix
Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
RATIONALE: An orientation and patient education program and telephone counseling may help improve the quality of life in patients with peritoneal surface malignancies.
- Conditions
- Advanced Malignant Mesothelioma, Carcinoma of the Appendix, Ovarian Sarcoma, Ovarian Stromal Cancer
- Trial name
- HOPE (NCT01126346)
- Testing
- HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Appendix
Closure of Appendicular Stump
this study compare between different types of appendicular stump closure
- Trial name
- NCT07229690
- Testing
- endoloop closure, intracorporeal suture
- Where
- Egypt
- Volunteers
- 666 people
- Sponsor
- Zagazig University