Clinical trials: Appropriateness
Adverse Drug Reaction (ADR)
The INTEGRATE Study: Integrated Pharmacogenetics, TDM and Active Pharmacovigilance as Innovative Tools for the Optimisation and Appropriateness of Drug Therapy
The primary goal of this observational study is to evaluate the feasibility of implementing a multidisciplinary approach based on pharmacogenetics, TDM (Therapeutic Drug Monitoring) and MedReview into the clinical practice in…
- Trial name
- INTEGRATE (NCT06822959)
- Testing
- Pharmacogenetics, TDM and MedReview
- Where
- 2 sites in Italy
- Volunteers
- 450 people
- Sponsor
- Direzione centrale salute, politiche sociali e disabilità
Fever, Acute Pain
Using a Decision-making System to Support the Management of Fever and Acute Pain in Children
FEVER is a single-center, prospective, open-label, pre-market, pivotal, single-arm study aimed at demonstrating how the use of an algorithm integrated with a Class I Medical Device (Puntofarma®), which is made available through a…
- Trial name
- FEVER (NCT07344090)
- Testing
- Puntofarma® FEVER
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Qwince Innovation S.r.l.
Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes
Appropriateness of Coronary Angioplasty in PAtients With isCHEmic Heart Disease
An observational, retrospective, multicenter, blinded adjudication study to evaluate the clinical appropriateness of Percutaneous Coronary Intervention (PCI) indication and execution in patients with stable Coronary Artery…
- Conditions
- Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes, NSTEMI, Unstable Angina
- Trial name
- APACHE (NCT02748603)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Italian Society of Invasive Cardiology
Children,Hospitalized, Vascular Access Devices
Implementation and Evaluation of the Selection Scheme of Peripheral Venous Infusion Devices for Hospitalized Children
This study is a stepped wedge cluster randomized trial design. The object is to evaluate the influence on patient outcomes, medical staff's evidence-based practice behavior and hospital context after implementation of the…
- Trial name
- NCT05378568
- Testing
- the selection scheme of peripheral venous access devices, the existing nursing routine
- Where
- China
- Volunteers
- 4,652 people
- Sponsor
- Children's Hospital of Fudan University
Acquisition of Literacy Skills for All Children, Including Those With SLDs, Appropriateness of Referrals for SLD Assessment for Accurate Early Detection of SLDs
Literacy Skills Improvement and Early Diagnosis of Specific Learning Disorders (SLD) Using a New Phono Syllabic Program
Scientific evidence shows that systematic phonological approaches are more effective than other methods in teaching children to read and should therefore be adopted in schools.
- Trial name
- ALFABETO (NCT07510126)
- Testing
- Alfabeto program, Other literacy teaching methods
- Where
- Italy
- Volunteers
- 1,407 people
- Sponsor
- IRCCS Burlo Garofolo
Inappropriate Prescribing, Primary Health Care
Deprescribing in Primary Health Care
Medications can help older adults but can also harm them. Frail older adults tend to have many health problems that require treatment, but are also at risk of harm from the medications prescribed.
- Conditions
- Inappropriate Prescribing, Primary Health Care, Polypharmacy
- Trial name
- NCT03903484
- Testing
- Deprescribing toolbox and intervention
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Behavior Problem, Behavior, Child
Effectiveness of an Online Parenting Training
Child and adolescent behavioral health problems are related to the leading causes of youth morbidity and mortality. Parent-focused preventive interventions, such as GenerationPMTO (GenPMTO), effectively prevent behavioral health…
- Conditions
- Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
- Trial name
- NCT05111886
- Testing
- Communication Skills Training, eHealth GenPMTO, Written Referral Process
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Metastatic Breast Cancer, End of Life
Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
I this qualitative study, Investigators will conduct semi-structured interviews with clinicians that are involved in the care of patients with breast cancer to evaluate the acceptability, appropriateness, and…
- Trial name
- NCT05440929
- Testing
- Clinician Qualitative Interview
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Parent Child Relationship, Parenting Intervention
The New Beginnings Podcast: Brief Audio Intervention for Parents From Divorced and Separated Families
The goal of this study is to learn if the New Beginnings Podcast can help children whose parents are going through a divorce or separation.
- Conditions
- Parent Child Relationship, Parenting Intervention, Parenting Behaviour, Interparental Conflict
- Trial name
- NBP-P (NCT07529548)
- Testing
- New Beginnings Podcast Program, No Interventions
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Charla Aubrey Rhodes
IV Oral Switch, Appropriateness Review
Switch Timely to Oral Medication
The goal of this study compare the effectiveness of an electronic note versus a telephone call to alert the prescriber of a possible IV to oral switch.
- Trial name
- STORM (NCT03254407)
- Testing
- Screening medical record
- Where
- Belgium
- Volunteers
- 8,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy Volunteers Only
Determining Age Appropriateness of Children's Products and Toys
Background: Play during childhood is an important part of healthy development, and children can learn many things when they play. Much of the time that children spend playing is with toys.
- Trial name
- NCT02544035
- Testing
- Type of Toy, Play Partner
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Trauma, Psychological, Trauma and Stressor Related Disorders
Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)
Trauma-focused cognitive behavior therapy (TF-CBT) has the strongest evidence of any clinical intervention for youth trauma but is rarely adopted in the education sector - the most common setting for youth mental healthcare.
- Trial name
- NCT06941428
- Testing
- Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Washington
Blood Component Transfusion
Appropriateness of Frozen Plasma Use in Canada
There is little evidence to guide the current use of Frozen Plasma. Despite this, over 260,000 units of frozen plasma are transfused in Canada annually.
- Trial name
- NCT01187030
- Volunteers
- 2,580 people
- Sponsor
- Ottawa Hospital Research Institute
Antimicrobial Stewardship, Urinary Tract Infections
Nurse-led Antimicrobial Stewardship Intervention to Increase Antibiotic Appropriateness in Residential Aged Care Facilities
The study will explore the impact of a nurse-led bundled antimicrobial stewardship intervention on the appropriateness of antimicrobial use in residential aged care facilities.
- Conditions
- Antimicrobial Stewardship, Urinary Tract Infections, Respiratory Tract Infections, Skin and Soft Tissue Infections
- Trial name
- NCT03941509
- Testing
- Antimicrobial stewardship
- Where
- Australia
- Volunteers
- 700 people
- Sponsor
- Bayside Health
Anti-Infectives Adverse Reaction
Appropriateness of Intravenous Antibiotics Prescriptions at Hospital Discharge
A quasi-experimental study was conducted among patients receiving care at the medicine units of the Maharaj Nakorn Chiang Mai Hospital to determine the appropriateness of intravenous antibiotics at hospital discharge with and…
- Trial name
- NCT03173768
- Testing
- ID specialist approval
- Where
- Thailand
- Volunteers
- 173 people
- Sponsor
- Chiang Mai University
Appropriateness of Prescribing in Older Patients
RCT Assessing the Impact of Online Training on Doctors' Prescribing for Older Patients
This study will assess, by means of a randomized controlled trial, the impact of an online educational tool, on doctors' knowledge and confidence with regards to prescribing for older patients.
- Trial name
- NCT02405975
- Testing
- SCRIPT
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- University College Cork
Morbid Obesity
Study on the Appropriateness of Bariatric Surgery in Adolescents
single-center study carried out in order to evaluate in prospective among patients seen or treated in the pediatric endocrinology unit and multidisciplinary management of obesity, the potential number of patients eligible for…
- Trial name
- NCT01249950
- Testing
- feasibility
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Nursing Workload
ICU Nurses' Perspectives on a Nursing Workload Dashboard
Increasing patient complexity, staffing shortages, and administrative burdens have intensified nurses' workloads, contributing to burnout and reduced job satisfaction.
- Trial name
- NCT07173218
- Volunteers
- 60 people
- Sponsor
- Willemijn Berkhout
Pulmonary Rehabilitation, Physical Activities
Feasibility of Integrating Street Racket Into Ambulatory Pulmonary Rehabilitation
This study looks at whether Street Racket is a feasable activity that can be added to pulmonary rehabilitation for people with chronic lung disease.
- Conditions
- Pulmonary Rehabilitation, Physical Activities, Exercise Therapy
- Trial name
- APRacket (NCT07430943)
- Testing
- Street Racket
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- Mona Lichtblau
Echocardiography
Clinical Reminder to Improve Appropriateness of Echocardiography
This study will test a clinical reminder to show recent echocardiograms when a new echocardiogram is ordered. The goal is to avoid unnecessary comprehensive echocardiography.
- Trial name
- NCT04925245
- Testing
- Clinical Reminder
- Where
- United States
- Volunteers
- 1,365 people
- Sponsor
- Stanford University