Clinical trials: Arthritis of Knee
Osteoarthritis, Knee
MOTION Clinical Trial
Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment.
- Trial name
- NCT06843980
- Testing
- MISHA Knee System, Non-Surgical Treatment
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- Moximed
Osteoarthritis
Study of AQUACEL™ Ag Surgical Cover Dressing Following Total Knee Replacement
The aim of the study is to determine whether the AQUACEL™ Ag SURGICAL cover dressing is successful in reducing the incidence of wound infection in high risk patients following total knee replacement.
- Trial name
- NCT02217202
- Testing
- Aquacel Ag dressing
- Sponsor
- Golden Jubilee National Hospital
Knee Pain Chronic, Osteo Arthritis Knee
Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.
This is an Individual Patient Expanded Access IND of autologous adipose derived Mesenchymal Stem Cells with the primary goal of treating 1 individual with bilateral knee pain who has exhausted all treatment options, his condition…
- Trial name
- NCT04604288
- Testing
- HB-adMSC
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Juvenile Idiopathic Arthritis, Persistent Knee Arthritis
Genicular Nerve Block in Juvenile Idiopathic Arthritis
N=104 juvenile idiopathic arthritis patients diagnosed after ILAR criteria with unilateral persistent knee arthritis. They will be randomly assigned into two groups; group 1 will receive genicular nerve block, group 2…
- Conditions
- Juvenile Idiopathic Arthritis, Persistent Knee Arthritis, no Intra-articular Injection in the Last 3 Months, no Other Cause for Chronic Kneearthritis
- Trial name
- NCT04687930
- Testing
- genicular nerve block, intra-articular steroid injection
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Sohag University
Osteoarthritis, Knee
Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy
The objective of this study was to evaluate the safety and efficacy of topical combined with intravenous tranexamic acid for high tibial osteotomy without placement of a drainage tube The clinical scores of patients and their…
- Trial name
- NCT03954860
- Testing
- Drainage Tube, Tranexamic Acid, Sodium Chloride 0.9%
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
Knee Osteoarthritis
Influence of Manual Physical Therapy on Habitual Activity in Knee Osteoarthritis
The investigators assessed overall physical activity and sleep quality in subjects with knee osteoarthritis(OA) at baseline, and at four and 12 weeks following initiation of physical therapy.
- Trial name
- NCT03573141
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brooke Army Medical Center
Osteoarthritis, Traumatic Arthritis
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
The purpose of the study is to assess the long-term performance of the NexGen LPS-Flex Mobile Bearing Knee in the treatment of patients with severe knee pain or degenerative knee disease.
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus
- Trial name
- NCT00854295
- Testing
- NexGen LPS-Flex Mobile Bearing Knee
- Where
- 3 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Osteoarthritis
Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee
To demonstrate that new drugs work, many complex multidose studies are often required. The intent of this study is to use Ibuprofen as an example of a marketed pain relief drug to validate a simpler single dose model for future…
- Trial name
- NCT00372801
- Testing
- Ibuprofen
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis
Assessment of Wrist Joint and Knee Joint Inflammation in Patients With Rheumatoid Arthritis by Quantitative Three Dimensional Power Doppler Ultrasonography
The purpose of this study is to: 1. To investigate the wrist joint synovial blood flow intensity and model by quantitative three-dimensional (3D) power Doppler ultrasonography (PDUS) in patients with rheumatoid arthritis before…
- Trial name
- 3D sono in RA (NCT00858169)
- Volunteers
- 49 people
- Sponsor
- Taichung Veterans General Hospital
Osteoarthritis, Arthralgia
Leeches for the Treatment of Knee Osteoarthritis
Previous studies have not addressed the question, whether or not a repeated leeching can supply symptomatic relief of osteoarthritic pain for extended periods of time.
- Trial name
- NCT00435773
- Testing
- Single Leeching, Repeated Leeching after 4 weeks
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- RWTH Aachen University
Rheumatoid Arthritis
Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis
Osteoarthritis of the knee is one of the most common causes of disability among elderly. Arthritis rheumatoid is an autoimmune disease which causes multi articular arthritis, such as knee osteoarthritis.
- Trial name
- NCT01873625
- Testing
- mesenchymal cell transplantation
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Meniscus Rupture, Meniscus Injury
Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces.
- Conditions
- Meniscus Rupture, Meniscus Injury, Osteoarthritis of Knee
- Trial name
- NCT07079254
- Testing
- Meniscus suture, Partial meniscectomy
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Knee Osteoarthritis
The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise
The purpose of the study is to explore if a subgroup of people with osteoarthritic knees can be identified using the McKenzie System of Mechanical Diagnosis and Therapy.
- Trial name
- NCT01641874
- Testing
- Exercise, Evidence based exercise
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Retrospective Follow-up Study of Synvisc® in Patients With Knee Osteoarthritis
Retrospective collection of data, aimed at a better knowledge of the use of Synvisc® among the patients with knee osteoarthritis (OA) since at least three years.
- Trial name
- NCT02195557
- Testing
- Synvisc®
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Osteoarthritis, Knee
Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II
Recently, E.Motion-PS-Pro (B.Braun-Aesculap, Tuttlingen, Germany), a new mobile bearing knee system with a unique ball and socket post-cam mechanism was developed for use in total knee arthroplasty.
- Trial name
- NCT02276118
- Testing
- device: e.motion PS Pro, device : Genesis II
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Osteoarthritis Knee
Effectivity of Allogenic Umbilical Cord Mesenchymal Stem Cells Conditioned Media for Osteoarthritis of the Knee Joint
Osteoarthritis (OA) is a joint disorder that often occurs and causes disability. This disorder is characterized by an inflammatory reaction in the synovial joints accompanied by a gradual degeneration process in the articular…
- Trial name
- NCT06688318
- Testing
- Intra-articular secretome injection therapy
- Where
- Indonesia
- Volunteers
- 11 people
- Sponsor
- Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
Osteoarthritis of Knee
Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis
Primary aim: evaluate efficacy of intra-articular injection of etanercept for moderate and severe knee osteoarthritis. Second aim: investigate the potentiality of serum cytokines (TNF-α, Interleukin 1-α (IL1-α), IL1-β, matrix…
- Trial name
- EIAIETNKOA (NCT02722772)
- Testing
- Etanercept, Health education, exercise and diet guidance
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Knee Osteoarthritis
Custom Guides for Total Knee Arthroplasty (TKA)
The goal of the study is to know if the reconstruction of the lower limb mechanical axis and the patient knee function is improved after Total Knee Arthroplasty (TKA) using patient specific instruments.
- Trial name
- NCT01573208
- Testing
- Custom guides
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Lausanne Hospitals
Osteoarthritis, Knee
Patients' Perceptions of Assessment and Treatment of Knee Osteoarthritis in Primary Care
Background: To diagnose osteoarthritis (OA), Swedish guidelines recommend an overall assessment including patient history, symptoms, and clinical findings. However, diagnostic radiography is not recommended when assessing OA.
- Trial name
- NCT05566925
- Testing
- Direct access to physiotherapist for assessment, diagnosis and treatment.
- Where
- 2 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Vastra Gotaland Region