Clinical trials: Articular Cartilage Injury
Defect of Articular Cartilage, Articular Cartilage Disorder of Knee
the Safety and Efficacy Evaluation of Chondron Compared With Mircrofracture of Knee
The purpose of this study is to evaluate safety and efficacy of Chondron(autologous cultured Chondrocyte) by comparing between Chondron implantation and Microfracture.
- Conditions
- Defect of Articular Cartilage, Articular Cartilage Disorder of Knee, Degeneration; Articular Cartilage, Knee
- Trial name
- NCT02524509
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Cartilage Injury, Cartilage Damage
ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry
The primary objective of this registry is to obtain long-term outcomes on ProChondrix CR in cartilage repair procedures of the knee, ankle, foot and hip.
- Trial name
- NCT04301258
- Testing
- Articular cartilage repair
- Where
- 5 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AlloSource
Osteoarthritis
Developing Allogeneic Musculoskeletal Therapies
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other…
- Trial name
- NCT06167928
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Keele University
Defect of Articular Cartilage, Cartilage Injury
Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair
This is a proof-of-concept study to determine the safety and efficacy of a novel device to increase the reparative capacity of the knee.
- Conditions
- Defect of Articular Cartilage, Cartilage Injury, Osteoarthritis, Knee
- Trial name
- AURA (NCT02696876)
- Testing
- Arthroscopic synovial brushing, Microfracture
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Leeds
Cartilage Loss, Microfracture
Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects
The study will examine clinical and radiographic outcomes of microfracture surgery (a common technique to address isolated areas of cartilage loss) in the knee used with or without unloader bracing.
- Trial name
- Mfxbracing (NCT02016300)
- Testing
- Unloader Bracing, Non-Bracing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Defect of Articular Cartilage, Osteoarthritis
Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using…
- Conditions
- Defect of Articular Cartilage, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539030
- Testing
- Microfracture, CartiFill
- Where
- 12 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Anterior Cruciate Ligament Rupture
Initial Graft Tension and ACL Surgery
The anterior cruciate ligament (ACL) is one of four strong ligaments connecting the bones of the knee joint. If overstretched, the ACL can tear. Reconstruction of a torn ACL is now a common surgical procedure.
- Trial name
- NCT00434837
- Testing
- Initial graft tension during ACL reconstruction surgery
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Acute Injury of Anterior Cruciate Ligament
Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury
This study will evaluate the bio-mechanical and biochemical abnormalities in acute ACL-injured knees over time. Data will be collected through advanced quantitative MR imaging, functional testing, and bio-specimen collection.
- Trial name
- NCT02010125
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
Gait Rehabilitation to Treat FastOA
The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee
- Trial name
- NCT05848622
- Testing
- Real-time gait biofeedback
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Carolina, Chapel Hill
Defect of Articular Cartilage
the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture in patients with cartilage defects in their ankles.
- Trial name
- NCT02519881
- Testing
- Microfracture, CartiFill
- Where
- 3 sites in South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Anterior Cruciate Ligament Injuries, Cartilage Degeneration
The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
Explore The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
- Trial name
- NCT04968665
- Testing
- gait testing, functional MRI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Lateral Patellar Compression Syndrome, Patellar Dislocation
Tactile Guided Lateral Patellar Release
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin.
- Conditions
- Lateral Patellar Compression Syndrome, Patellar Dislocation, Patellar (or Kneecap) Instability and Mal-alignment, Patella Alta
- Trial name
- TGLPR (NCT07637344)
- Testing
- Percutaneous lateral retinacular release of the patella
- Volunteers
- 23 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.