Clinical trials: Atopic Disorders
Atopic Dermatitis
Effectiveness of Melatonin for Sleep Disturbances in Children With Atopic Dermatitis
Sleep disturbance is a common complaint among patients with atopic dermatitis(AD). Melatonin may aid sleep and also has anti-inflammatory properties, and has been suggested in managing sleep disturbance in AD patients.
- Trial name
- NCT01638234
- Testing
- Melatonin
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colic, Healthy Infants
Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns.
This study aims to demonstrate that a dietary supplement, which contains two strains of the probiotic L. reuteri is safe, well tolerated and able to reduce the incidence of colic and excessive crying/fussiness in healthy infants.
- Conditions
- Colic, Healthy Infants, Eczema Atopic Dermatitis
- Trial name
- ProtectPrevent (NCT07347743)
- Testing
- Two probiotic Limosilactobacillus reuteri strains
- Where
- Belgium
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Food Hypersensitivity, Asthma in Children
Toxicity of Micro and Nano Plastics Combined With Environmental Contaminants on the Risk of Allergic Disease
Single-center, cross-sectional, longitudinal, observational, population based cohort study with stratified sample (by age group, gender, and residential area).
- Conditions
- Food Hypersensitivity, Asthma in Children, Rhinitis, Allergic, Dermatitis, Atopic
- Trial name
- Imptox (NCT05177744)
- Where
- Croatia
- Volunteers
- 1,156 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Srebrnjak
Atopic Dermatitis
Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis
Atopic dermatitis (AD), also known as eczema, is a common chronic inflammatory skin disease that usually begins in infancy and causes significant itching, discomfort, and sleep disturbance.
- Trial name
- PROTEGO (NCT07333378)
- Testing
- Retention of Vernix Caseosa After Birth, Removal of Vernix Caseosa After Birth
- Where
- 2 sites in Chile
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Atopic Dermatitis
Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel
The purpose for this study is to assess the Safety and Efficacy of Daily Application for 4 weeks of DBI-001 Gel Versus Aqueous Gel in Subjects with Atopic Dermatitis
- Trial name
- NCT05253755
- Testing
- DBI-001, Aqueous gel
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DermBiont, Inc.
Dermatitis Atopic
A Study to Assess the Reliability/Feasibility of Using Emerald Touchless Sensor for Scratching and Sleep Quantification in a Subset of Participants From PEDISTAD Study (OBS15333; NCT03687359)
Primary objective: To explore and quantify the association between nighttime scratching and sleep patterns objectively in pediatric participants with moderate to severe atopic dermatitis (AD) using an innovative Emerald touchless…
- Trial name
- NCT05235724
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- Sanofi
Asthma, Allergic Rhinitis
Evaluation of an Integrated Care Project
The purpose of the study is to investigate the effectiveness and cost-effectiveness of the integrated care program of a statutory health insurance offering additional homeopathic treatment to their members
- Conditions
- Asthma, Allergic Rhinitis, Atopic Eczema, Migraine
- Trial name
- ediva (NCT01854580)
- Where
- Germany
- Volunteers
- 3,960 people
- Sponsor
- Charite University, Berlin, Germany
Atopic Dermatitis, Eczema
A Study to Evaluate the Efficacy and Safety of HAT01H in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by a disturbance of epidermal-barrier function that results in intensely pruritic subacute and chronic eczematous plaques.
- Trial name
- NCT03089229
- Testing
- HAT01H Cream, Vehicle Cream
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Haus Bioceuticals
Dermatitis, Atopic
Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis
To assess the efficacy of Locobase REPAIR® when used in children with moderate to severe AD
- Trial name
- NCT00673725
- Testing
- Locobase® REPAIR
- Where
- 3 sites in United Kingdom
- Volunteers
- 49 people
- Sponsor
- Astellas Pharma Europe B.V.
Atopic Dermatitis
Study of Crisaborole Ointment 2% in Mild to Moderate Atopic Dermatitis
The purpose of this study is to document the timing of improvement in atopic dermatitis symptoms and severity following the application of crisaborole ointment 2% in patients 2 years or older with mild to moderate atopic…
- Trial name
- NCT04214197
- Testing
- Crisaborole 2% Top Oint
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Atopic Dermatitis
Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)
This is a Phase 1b, randomized, placebo/vehicle-controlled, double-blinded, multi-center trial. It is designed to assess the safety and efficacy of S.
- Trial name
- NCT06504160
- Testing
- ShA9 Topical Gel, Hydrocortisone Ointment, Clobetasol Ointment
- Where
- 8 sites in United States
- Volunteers
- 86 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Dermatitis
An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis
This study will compare the safety and efficacy of three test article foams (PDI-192 0.1% Foam, PDI-192 0.15% Foam, and Vehicle Foam) such that a final commercial product may be selected for future development.
- Trial name
- NCT01826461
- Testing
- PDI-192, Vehicle
- Where
- 9 sites in United States
- Volunteers
- 151 people
- Sponsor
- PreCision Dermatology, Inc.
Atopic Dermatitis
the Effectiveness of Probiotics on Atopic Dermatitis With Cow Milk Allergy
There is not enough evidence to support the use of probiotics for prevention or treatment of AD in children in clinical practice.
- Trial name
- NCT01045486
- Testing
- ATP mixed probiotics
- Volunteers
- 36 people
- Sponsor
- Soonchunhyang University Hospital
Dermatitis, Atopic
Evaluation of Cetaphil Advanced Usage to Control Light to Moderate Atopic Dermatitis, in Attempt to Reduce the Necessity of Topic Corticoids Application
The main goal of this present study is evaluate the decreasing of necessity of topic corticoids usage to control outbreaks of light to moderate atopic dermatitis by using the correct emollients.
- Trial name
- NCT01063218
- Testing
- Emollient - Cetaphil Advanced
- Where
- 2 sites in Brazil
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Galderma Brasil Ltda.
Atopic Dermatitis
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3)
The purpose of the study is to assess the efficacy and safety of ruxolitinib cream in children with Atopic Dermatitis. This is a randomized, double-blind, Vehicle Controlled study.
- Trial name
- NCT04921969
- Testing
- Ruxolitinib, Vehicle Cream
- Where
- 67 sites in United States, Canada
- Volunteers
- 330 people
- Sponsor
- Incyte Corporation
Atopic Dermatitis
A Long-term Data Collection Study of Participants in France Aged 6 Years Old or More With Atopic Dermatitis Receiving Dupilumab
This is a long-term study to collect data over 3 years in order to find out what is likely to happen in the future regarding participants 6 years of age and older who receive dupilumab for Atopic Dermatitis (AD) commonly known as…
- Trial name
- DUPILAB (NCT06169527)
- Testing
- Dupilumab
- Where
- 42 sites in France
- Volunteers
- 303 people
- Sponsor
- Sanofi
Atopic Dermatitis
Assessment of Pruritus Improvement With Pimecrolimus Treatment on the Areas Affected by Mild-to-moderate AD, in Patients 2- to 11- Year-old
The purpose of this study is to assess the efficacy and safety of pimecrolimus cream 1% in relation to the improvement of pruritus in pediatric patients (2- to 11- year-old) with mild to moderate atopic dermatitis.
- Trial name
- NCT00510003
- Testing
- Pimecrolimus
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Novartis Pharmaceuticals
Atopic Dermatitis
Study to Assess Efficacy and Safety of Two Regimens of Crisaborole Ointment 2% in Japanese Participants Aged ≥2 Years With Mild to Moderate Atopic Dermatitis
This is a Phase 2b, multi-center, randomized, double-blind, vehicle-controlled, intraparticipant study to evaluate efficacy and safety of two regimens of crisaborole ointment 2% in Japanese pediatric and adult participants…
- Trial name
- NCT03954158
- Testing
- Crisaborole ointment 2%, Vehicle
- Where
- 3 sites in Japan
- Volunteers
- 81 people
- Sponsor
- Pfizer
Moderate to Severe Atopic Dermatitis
Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis
The study was designed to test the hypothesis whether a standardized, time-and score-oriented treatment following a strict evidence based algorithm is equally effective to a standard treatment regimen for moderate to severe…
- Trial name
- NCT00148746
- Testing
- Pimecrolimus, Tacrolimus, Prednisolone
- Where
- Germany
- Sponsor
- Technische Universität Dresden
Atopic Dermatitis (AD)
A Phase 3 Trial of OPA-15406 Foam in Children and Infants With Atopic Dermatitis
To investigate the superiority of 0.3% OPA-15406 foam to the vehicle in children with atopic dermatitis (AD)
- Trial name
- NCT07184645
- Testing
- OPA-15406, Vehicle
- Where
- Japan
- Volunteers
- 198 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.