Clinical trials: Atopy
Dermatitis, Atopic, Eczema
A Study of Lebrikizumab in Combination With Topical Corticosteroids in Patients With Atopic Dermatitis (AD) That Are Not Adequately Controlled With or Are Non-eligible for Cyclosporine
The main purpose of this study is to evaluate the efficacy of lebrikizumab compared with placebo in participants not adequately controlled with cyclosporine or for whom cyclosporine is not medically advisable up to Week 16.
- Trial name
- ADvantage (NCT05149313)
- Testing
- Lebrikizumab
- Where
- 48 sites in Austria, Belgium and 6 more
- Volunteers
- 331 people
- Sponsor
- Almirall, S.A.
Atopic Dermatitis
Efficacy of Oral Supplementation of Probiotics in Children With Atopic Dermatitis
Various clinical studies have evaluated the role of probiotics in children with atopic dermatitis, with some studies showing improvement in clinical outcome after supplementation of probiotics and others showing no additional…
- Trial name
- NCT04706559
- Testing
- Probiotic sachet containing mixture of four strains i.e.Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium longum, and Saccharomyces boulardii, Conventional treatment
- Where
- Nepal
- Volunteers
- 98 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Atopic Hand and Foot Dermatitis
A Study to Investigate the Efficacy and Safety of Lebrikizumab in Participants With Moderate-to-Severe Atopic Hand and Foot Dermatitis
The main purpose of this study is to assess the efficacy of lebrikizumab versus placebo on skin lesions in adults and adolescent participants with atopic hand and foot dermatitis.
- Trial name
- ADtouch (NCT06921759)
- Testing
- Lebrikizumab
- Where
- 76 sites in United States, Argentina and 6 more
- Volunteers
- 221 people
- Sponsor
- Eli Lilly and Company
Allergy, Asthma
Early Origins of Allergy and Asthma
Birth cohort study with recruitment during pregnancy to determine prenatal and perinatal conditions, as well as genetic and epigenetic factors, that participate in the early setting of immune responses, and the role of these in…
- Conditions
- Allergy, Asthma, Food Allergy, Allergic Sensitisation
- Trial name
- ARIES (NCT04186949)
- Where
- Chile
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Atopic Dermatitis
Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
AD is a disease found in children; the focus of the study is the mechanisms associated in children with AD induced by food allergies.
- Trial name
- NCT00557284
- Testing
- Montelukast
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- 1st Allergy & Clinical Research Center
Atopic Dermatitis, Eczema, Atopic
Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream for Very Dry, Irritated to Atopic Sensitive Skin.
Multicentric, double blind, randomized, comparative study with two parallel group: study group vs placebo group. 5 visits: inclusion visit [day (D) 0] and 4 follow-up visits (D30, D60, D90, and D120).
- Trial name
- NCT05575882
- Testing
- Skin hydration, Barrier function measurement, Potential of hydrogen measurement (pH)
- Where
- 3 sites in Argentina, India and 1 more
- Volunteers
- 100 people
- Sponsor
- NAOS Argentina S.A.
Atopic Dermatitis
Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA)
The purpose of this trial is to evaluate the efficacy and safety of tralokinumab administered as subcutaneous (SC) injection by an autoinjector in adults and adolescents (age 12 to 17 years) with moderate-to-severe atopic…
- Trial name
- INJECZTRA (NCT05194540)
- Testing
- Tralokinumab
- Where
- 29 sites in United States
- Volunteers
- 136 people
- Sponsor
- LEO Pharma
Asthma, Atopy
The JOIN Project: The Air in Diagnosis and Prevention of Asthma and Allergy
The JOIN project combines the health and indoor environment research areas to contribute in the development and validation of a new asthma diagnosis method through exhaled VOC analysis.
- Trial name
- JOIN (NCT02802891)
- Where
- Portugal
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Atopic Dermatitis
Registry for Systemic Eczema Treatments
The Registry for Systemic Eczema Therapies (RESET) registry is a database and biospecimen repository for patients with pediatric-onset atopic dermatitis (AD) who have used or will initiate any systemic treatment(s) for AD.
- Trial name
- RESET (NCT06136767)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Atopic Dermatitis
Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis
This study is not being conducted in the United States of America (USA). Atopic dermatitis, also called eczema, is characterized by redness, papulation (skin elevation) and pruritus (skin itching).
- Trial name
- NCT00130364
- Testing
- Pimecrolimus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Novartis
Atopic Dermatitis
A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis
The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).
- Trial name
- NCT03257644
- Testing
- Ruxolitinib phosphate cream
- Where
- 23 sites in United States
- Volunteers
- 70 people
- Sponsor
- Incyte Corporation
Dermatitis Atopic
Evaluation of Biomarkers of Atopic Dermatitis in Pediatric Patients (PEDISTAD BIOMARKER STUDY)
Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: Disease state and time course of AD, Disease state and evolution of selected atopic comorbid conditions, Effectiveness of specific AD…
- Trial name
- NCT03849716
- Testing
- Blood sample, Cheek swab
- Where
- 48 sites in United States, Argentina and 7 more
- Volunteers
- 266 people
- Sponsor
- Sanofi
Atopic Dermatitis, Secondary Infection
Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis
Skin infections may complicate the treatment of atopic dermatitis.The use of topical ointments has become very important to avoid the use of oral antibiotics.
- Trial name
- NCT01064947
- Testing
- Retapamulin 1%
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Derm Research, PLLC
Atopic Dermatitis, Eczema
Evaluating Skin Barrier Dysfunction in Infants at High Risk of Atopy
It is hypothesized that food allergy is preceded by atopic dermatitis (AD), due to a disruption of skin barrier which can predispose one to food sensitization through the skin.
- Conditions
- Atopic Dermatitis, Eczema, Food Allergy
- Trial name
- NCT03089476
- Testing
- Evaluating atopy in infants, Evaluating TEWL and STS in adults
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Jewish Health
Atopic Dermatitis (AD), Atopic Dermatitis (Eczema)
Global Healthcare Study on Atopic Dermatitis
The Global Healthcare Study on Atopic Dermatitis (GHSAD) is an international, multicenter observational study hosted by the University of Zurich (UZH) investigating healthcare access, treatment patterns, disease severity, and…
- Trial name
- GHSAD (NCT07659756)
- Where
- Switzerland
- Volunteers
- 9,600 people
- Sponsor
- Julia Tatjana Maul
Asthma, Lung Function Decreased
Dietary Intake in Adults From the GA2LEN Folow-up Survey
The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
- Conditions
- Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation
- Trial name
- NCT03251157
- Testing
- Dietary intake of various nutrients, foods and biocompounds
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Atopic Dermatitis
Treatment and Medical Care of Patients With Moderate-to-severe Atopic Dermatitis - TREATswitzerland
As structured and detailed data on the management of AD, a common chronic inflammatory skin disease which has a high impact on patients' quality of life and socioeconomic burden, are not available in Switzerland, the planned…
- Trial name
- NCT05819463
- Where
- 9 sites in Switzerland
- Volunteers
- 700 people
- Sponsor
- Swiss Society of Dermatology and Venereology
Atopic Dermatitis, Pruritus
Scratch and Sleep Quantification in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic type of eczema affecting approximately 10% of adults and 12% of children in the US. The intense itching (pruritus) associated with AD can be significantly disruptive to sleep and quality of…
- Conditions
- Atopic Dermatitis, Pruritus, Sleep Disturbance
- Trial name
- SQUAD (NCT03490877)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester
Atopic Dermatitis (AD)
MH004 Ointment in Healthy Adult Volunteers and Participants With Mild to Moderate Atopic Dermatitis
This is a Phase I/II Study of MH004 in Healthy Adult Volunteers, participants with Mild to Moderate Atopic Dermatitis.
- Trial name
- NCT07182864
- Testing
- MH004 0.1% Ointment, MH004 0.3% Ointment, MH004 1.0% Ointment
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Minghui Pharmaceutical (Hangzhou) Ltd
Atopic Dermatitis (AD)
Treatment of Moderate-to-Severe Atopic Dermatitis With Ivarmacitinib in Adolescents and Adults
Atopic dermatitis (AD) is a skin condition characterized by a rash and itching, resulting from skin inflammation. Ivarmacitinib is an approved medication for treating AD.
- Trial name
- NCT07276620
- Testing
- Ivarmacitinib Sulfate Tablets
- Volunteers
- 1,000 people
- Sponsor
- Xiangya Hospital of Central South University