Clinical trials: Augmentation
Fragile X Syndrome
Randomized Controlled Study of Donepezil in Fragile X Syndrome
Fragile X syndrome (FraX) is the most common known heritable cause of human intellectual disability. Though recent research has revealed much about the genetic and neurobiological bases of FraX, knowledge about specific and…
- Trial name
- NCT01120626
- Testing
- donepezil, sugar pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Duchenne Muscular Dystrophy, Spinal Muscular Atrophy
Optimum Insufflation Capacity in NMD
Patients with underlying neuromuscular disorder (NMD) often suffer from weakness in the inspiratory and expiratory muscles. Consequently they do not have the strength to generate the minimum flow of 160 to 300 liters/minute for…
- Conditions
- Duchenne Muscular Dystrophy, Spinal Muscular Atrophy, Chronic Respiratory Insufficiency
- Trial name
- NCT01981915
- Testing
- IPPB, LIAM
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Universität Duisburg-Essen
Glaucoma
AGV Implantation With Ologen in Pediatric Glaucomas
Ahmed Glaucoma Valve Implantation with Ologen augmentation in secondary pediatric glaucomas: A 2-year randomized controlled trial. Background: Many studies have investigated the clinical benefits of Ologen for trabeculectomy.
- Trial name
- NCT05014386
- Testing
- Ahmed Glaucoma Valve Implantation in secondary pediatric glaucomas., Ahmed Glaucoma Valve Implantation with Ologen augmentation in secondary pediatric glaucomas
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Psychiatric Disorders, Anxiety Disorders
Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety
Background: Anxiety disorders are becoming more common among children and teenagers. Anxiety can lead to long-term physical and mental problems, such as depression.
- Trial name
- NCT06595953
- Testing
- Gaze-Contingent Music Reward Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bone Graft, Keratinized Tissue
Open Membrane Technique as an Innovative Minimally Invasive Technique for Bone Augmentation
Sixteen patients with horizontal deficiencies in the posterior mandible were treated with "the Open Membrane Technique" (OMT). Dense PTFE membranes covering an allograft biomaterial were used without any attempt to passivate the…
- Trial name
- NCT07386301
- Testing
- Bone Augmentation
- Where
- Lebanon
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Cleft Grafting
Assessment of Bone Volume Using Patient Specific Autogenous Bone Plug Versus Particulate Autogenous Bone for Unilateral Alveolar Ridge Reconstruction
Most common complications that arise from alveolar cleft repair surgeries are; failure of graft integration, wound dehiscence, scar tissue formation, infections, bone exposure and oral-nasal fistula formation.
- Trial name
- NCT07137975
- Testing
- autogenous bone plug, regular autogenous bone grafting
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Massive Rotator Cuff Tears, Rotator Cuff Injuries
Irreparable Rotator Cuff Tears Treatment. Comparison of Two Methods: With and Without Biceps Tendon Augmentation
Management of massive rotator cuff tears (MRCT) is associated with high rates of failure. The long head of the biceps tendon augmentation (LHBTA) by reinforcement of the reconstruction and additional blood supply may improve…
- Conditions
- Massive Rotator Cuff Tears, Rotator Cuff Injuries, Shoulder Pain Chronic
- Trial name
- NCT05001581
- Testing
- Arthroscopic partial repair of massive rotator cuff tear, Arthroscopic partial repair of rotator cuff with biceps augmentation
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Saint Lucas Hospital, Poland
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Alveolar Cleft Grafting
Alveolar Cleft Grafting Using Two Different Alloplastic Grafts
P-patients with unilateral alveolar clefts I-purabone with -β-tricalcium phosphate graft C-β-tricalcium phosphate graft alone O-clinical out come Outcome name Measurement device Measurement unit Esthetic satisfaction (Primary…
- Trial name
- NCT03016793
- Testing
- Puerarin, β- tricalcium phosphate, β- tricalcium phosphate alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sickle Cell Disease
Arterial Function Parameters and Transcranial Doppler Velocity in Paediatric Patients With Sickle Cell Disease
Structural and functional changes in arteries are increasingly being recognized as significant features of sickle cell disease. This study aims to determine whether there are differences in arterial function parameters between…
- Trial name
- AFAT (NCT05748717)
- Where
- Jamaica
- Volunteers
- 34 people
- Sponsor
- The University of The West Indies
Bipolar Disorder
The Treatment of Children and Adolescents With Treatment-Resistant Depression
This study seeks to learn about brain function in adolescents with depression and to determine whether adding lithium carbonate to antidepressant medication can reduce depression in children and adolescents.
- Trial name
- NCT00029640
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health (NIMH)
Surgical Site Infection
Dressing Wear Time After Breast Augmentation With Prosthesis
This study was designed to determine whether the duration of dressing wear following augmentation mammaplasty influence skin colonization and eventually surgical site infections rates.
- Trial name
- NCT01553604
- Testing
- augmentation mammaplasty
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniela Francescato Veiga
Penile Skin, Buccal Mucosal Graft
Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture
The aim of this study is to analyze the outcomes of dorsal onlay buccal mucosal graft (BMG) and penile skin graft (PSG) urethroplasty in the management of long segment bulbar urethral stricture.
- Conditions
- Penile Skin, Buccal Mucosal Graft, Augmentation, Urethroplasty
- Trial name
- NCT07074717
- Testing
- Buccal Mucosal Graft (BMG) Urethroplasty, Penile Skin Graft (PSG) Urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Laparoscopic Cholecystectomy, Liver Ablation
Image Fusion in the OR
The objective of this study is to test the technical feasibility of LapAR visualization system for guiding laparoscopic surgeries and to gather clinical feedback on the use of this tool.
- Trial name
- NCT03670849
- Testing
- LapAR
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Raj Shekhar
Chronic Sinusitis, Open Sinus Elevation
Clinical and Radiographic Evidence of Alleviation of Preoperative Chronic Sinusitis After Open Sinus Allogeneic Bone Augmentation Surgery: A Retrospective Observational Study
The aim of this study is to evaluate the impact of open sinus elevation technique on chronic sinusitis when combined with simultaneous dental implant placement.
- Trial name
- NCT06773494
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Misr International University
Depressive Disorder
Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression
Depression is among the most prevalent psychiatric disorders, with an upward trend in its manifestation in younger individuals. In contrast to adult depression, adolescent depression often presents with longer attack durations…
- Trial name
- NCT06061653
- Testing
- IPT plus HD-tDCS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Craniofacial Microsomia
Clinical Trial of Fat Grafts Supplemented With Adipose-derived Regenerative Cells
Although first reports of the clinical use of adipose-derived regenerative cells (ADRC) suggest that this approach may be feasible and effective for soft tissue augmentation, there is a lack of randomized, controlled clinical…
- Trial name
- NCT01674439
- Testing
- Supplementation of ADRC, Without supplementation of ADRC
- Where
- Brazil
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Brachial Plexus Neuropathies
Human Amniotic Membrane and Mesenchymal Stem Cells Composite
The purpose of this clinical trial is to investigate the utility of composite wrapping comprising human amniotic membrane and allogeneic adipose-derived mesenchymal stem cells (HAM-AdMSC) for augmentation of nerve transfer…
- Trial name
- BPI+MSC (NCT04654286)
- Testing
- Nerve transfer procedure, Nerve transfer with HAM-AdMSC composite wrapping
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Open Sinus Elevation, Periapical Radiograph
A Standardized Novel Periapical Radiography Technique for Long Term Follow up of Implants Inserted Simultaneously With Sinus Allogenic Bone Augmentation
The Aim of this study is introducing a standardized novel periapical radiography technique for long term follow up of implants inserted simultaneously with sinus allogenic bone augmentation.
- Trial name
- NCT06773637
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Meniscal Tear
Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)
There are no current or past RCT comparing biologic augments for meniscal repair. There is good data supporting both the use of BMVP of the intercondylar notch and intra-articular PRP injections for augmentation of meniscal…
- Trial name
- NCT04775004
- Testing
- Bone marrow venting procedure (BMVP), Platelet Rich Plasma (PRP)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- University of Chicago