Clinical trials: Autistic Disorder in Children and Adolescents
Fragile X Syndrome, Autism Spectrum Disorder
Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders
Fragile X Syndrome (FXS) is a complex neurodevelopmental disorder caused by a mutation on the X chromosome. Scientists have investigated FXS extensively in both humans and animals.
- Conditions
- Fragile X Syndrome, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- ENTRAIN (NCT06227780)
- Testing
- Alpha Auditory Entrainment
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder (ASD)
Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved
Introduction: Adolescents with autism spectrum disorder (ASD) have more mental health problems than typically developping adolescents (without ASD).
- Trial name
- NCT07360223
- Testing
- Questionnaire and interview
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Autism Spectrum Disorder
Feasibility and Effectiveness of Computerized Cognitive Training in Adolescents With Autism Spectrum Disorder
The investigators will conduct a randomized placebo-controlled trial of a computerized intervention targeting cognition in 30 teens with autism spectrum disorder.
- Trial name
- MGHTCT (NCT02472860)
- Testing
- Targeted Cognitive Training (TCT), Youth Appropriate Online Games
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autistic Disorder
Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD).
This study will compare the effectiveness (how well the drug works) of aripiprazole, flexibly dosed with a placebo, in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).
- Trial name
- NCT00332241
- Testing
- Aripiprazole
- Where
- 9 sites in United States
- Volunteers
- 98 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism Spectrum Disorder
A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD)
For participants enrolled prior to Version 6 of the protocol: This was a Phase II multi-center, randomized, double-blind, 24-week, 3-arm, parallel group, placebo-controlled study to investigate the efficacy, safety, and…
- Trial name
- NCT02901431
- Testing
- RO5285119
- Where
- 45 sites in United States
- Volunteers
- 339 people
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorders
Investigating Phenotypic Profiles of Children and Adolescents With ASD
The purpose of this study is to provide a detailed description of language and cognitive profiles found among children and adolescents diagnosed with autism spectrum disorders (ASD).
- Trial name
- Phenotyping (NCT02700113)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston University Charles River Campus
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Vestibulo-Ocular Reflex for Balance and Stimming in Autism Spectrum Disorder
Autism spectrum disorder is a neurodevelopmental disorder that encompasses a number of disorders specifically affecting social skills, Communication and present with Rapid repetitive behaviors.
- Trial name
- NCT06340139
- Testing
- conventional treatment, experimental treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD)
Physiotherapy for Improving Mental Health in Children and Adolescents With ASD and ADHD
This study investigates whether a structured physiotherapy program can help reduce symptoms of stress, anxiety, and depression in children and adolescents diagnosed with Autism Spectrum Disorder (ASD) or…
- Conditions
- Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Neurodevelopmental Disorders
- Trial name
- NCT07231354
- Testing
- Structured Physiotherapy Program
- Where
- Greece
- Volunteers
- 117 people
- Sponsor
- International Hellenic University
Autistic Disorder
Aripiprazole Oral Solution in the Treatment of Children and Adolescents With Autistic Disorder
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, tolerability and the steady-state plasma trough concentration of aripiprazole flexible-dosed in children…
- Trial name
- NCT03487770
- Testing
- Aripiprazole Oral Solution
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Otsuka Beijing Research Institute
Autistic Disorder, Asperger Syndrome
Study of Aripiprazole to Treat Children and Adolescents With Autism
The purpose of this open label study in children and adolescents is to examine the acute and long-term effects of aripiprazole on problem behaviors associated with autism spectrum disorders and development in areas which appear…
- Conditions
- Autistic Disorder, Asperger Syndrome, Autism Spectrum Disorder
- Trial name
- PAIRS (NCT00619190)
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism
The Feasibility of a Remote Problem-Solving Intervention for Autistic Adolescents or Young Adults and a Caregiver
This project seeks to evaluate the feasibility and acceptability of a remote metacognitive strategy training intervention in transition-age autistic adolescents and young adults and a primary caregiver.
- Trial name
- NCT07216196
- Testing
- Pathways and Resources for Engagement and Participation (PREP)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Missouri-Columbia
Autistic Disorder
Motor Learning and Brain Changes in Autism
The purpose of this pilot study is to determine whether a video-game based motor training can affect postural stability, daily living skills, autism symptoms, and white matter microstructure of the corticospinal tract in…
- Trial name
- NCT02358317
- Testing
- Video Game Motor Training, Sedentary Video Game Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder High-Functioning
Establishment of Social Skills Training Group in Adolescents With Autism Spectrum Disorder and Effectiveness Analysis
Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction, and the presence of restricted, repetitive behavior and interests.
- Trial name
- NCT05341011
- Testing
- PEERS® Social Skills Training
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Cognitive and Emotional Processing of Social Stimuli in Children and Youth With Autism Spectrum Disorder
Children and youth diagnosed with autism spectrum disorder (ASD) have been shown to react abnormally to social stimuli, especially to human faces.
- Trial name
- NCT01322984
- Testing
- Pictures, Startle eliciting noise
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Autism Spectrum Disorder
Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of Gabapentin
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is increasing in prevalence, and is characterized by deficits in social communication and interaction across multiple contexts, and restricted, repetitive…
- Trial name
- NCT03589898
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Massachusetts, Worcester
ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder (ASD)
Biomarkers of ASD/ADHD and Factors Affecting Anxiety and Depression in Children and Young Adults
The PUREMIND OS1/OS2 study is a multinational, prospective, longitudinal observational study designed to identify early neurophysiological, biological, environmental, and psychosocial markers associated with neurodevelopmental…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder (ASD), Developmental Coordination Disorder (DCD)
- Trial name
- PUREMIND-OS (NCT07570381)
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Autism Disorder
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
A Randomized Placebo-Controlled TRIal of PPF3 vs. PlaCEbo in the TReatment of children and AdolescenTs with NeurOdeveloPmental DisorderS
- Trial name
- TRICERATOPS (NCT07893964)
- Testing
- PPF3
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital