Clinical trials: Autistic Spectrum Disorder
Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder
Neurodevelopmental Disorders in Youth With Criminal Behaviors
1. Describe the prevalence of neurodevelopmental disorders among youth with criminal behaviors 2. Explore the relationship between specific neurodevelopmental disorders and the rates and types of crime 3.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder, Conduct Disorders in Adolescence
- Trial name
- NCT05875363
- Testing
- collect data
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Sleep Initiation and Maintenance Disorders
Sensory-Friendly Physical Activity for Sleep in Autistic Children
Sleep problems are very common in children on the autism spectrum and can worsen daytime behaviour, learning, and family stress. Many families have limited access to specialist sleep services.
- Trial name
- SFPAS (NCT07277101)
- Testing
- Sensory-Friendly Physical Activity Program (PAP), Conventional control group
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Xili Wen
Neurodevelopmental Disorders, Autism
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare.
- Conditions
- Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- CALM (NCT06081348)
- Testing
- Sertraline
- Where
- 7 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)
In this project, the investigator will test the effect of augmenting an evidence based joint attention intervention (JASPER) with a motor-sound system intervention (PROMPT) compared to JASPER only on speech and language outcomes.
- Trial name
- BLOOM (NCT04218331)
- Testing
- JASPER, PROMPT
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)
ML-004-003 is a multi-center, open-label extension study that will enroll approximately 120 adolescent and adult subjects with ASD that have completed study ML-004-002.
- Trial name
- NCT05889273
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- MapLight Therapeutics
Autism Spectrum Disorder (ASD)
Exercise Efficacy on Autism Spectrum Disorder
The goal of this clinical trial is to learn if regular exercise intervention may improve the health status of the participants diagnosed with autism spectrum disorder, ages between 5-13 years old.
- Trial name
- NCT06831188
- Testing
- daily life exercise group, specific type exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Autism Spectrum Disorder
PRISM Intervention Study
This research study, Personalized, Responsive Intervention Sequences for Minimally Verbal Children with Autism (PRISM), is designed to maximize language outcomes for limited-language preschoolers, thereby lowering the risk of…
- Trial name
- NCT03883139
- Testing
- JASPER, DTT (Discrete Trial Training)
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Autism, Autism Spectrum Disorder
Biomarkers Research in Anxiety for Validation and Efficacy
A within-subjects design will be used for this preliminary investigation of four biomarkers across two contexts of use: prediction of treatment response (i.e., stratification) and quantification of response (i.e., change).
- Trial name
- BRAVE (NCT06221176)
- Testing
- Being Brave
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
Effectiveness of Caregiver-involved Group-based NDBIs Intervention for Autistic Preschoolers
This is a study that investigate the feasibility, acceptability, and preliminary efficacy of NDBIs for autistic preschoolers delivered in a group-setting.
- Trial name
- NCT06221943
- Testing
- Group-based Naturalistic Developmental Behavioral Intervention, One-on-one Naturalistic Developmental Behavioral Intervention, ASD Diagnosis
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder (ASD), Autism
Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism
The goal of this study is to compare two well-established early autism interventions, Early Start Denver Model (ESDM) and Pivotal Response Treatment (PRT), to better understand which approach is most effective for improving…
- Trial name
- NCT07522190
- Testing
- Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 7, who have been diagnosed with moderate to severe autism.
- Trial name
- NCT06359080
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder, Self Harm
Culturally Adapted Intervention to Prevent Self-harm in Young People With Autism
The goal of this feasibility randomized controlled trial is to assess the feasibility and acceptability of Youth Culturally Adapted Manually Assisted brief psychological intervention (YCMAP) in young people with autism in…
- Trial name
- NCT06591130
- Testing
- Youth culturally adapted manual assisted psychological intervention (Y-CMAP)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Living and Learning
Autism Spectrum Disorder, Autism
A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
The purpose of this study is to examine the effectiveness of pivotal response training (PRT) in an intensive center-based environment to treat social communication deficits in children with autism spectrum disorder (ASD).
- Trial name
- PRT-C (NCT03778827)
- Testing
- Intensive Center-Based Pivotal Response Treatment (PRT-C)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Autism, Autism Spectrum Disorder
A Study of Esomeprazole in Children With Autism
Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication and the presence of repetitive/stereotyped behaviors.
- Trial name
- NCT03866668
- Testing
- Esomeprazole
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Autism Spectrum Disorder, Restricted Behavior
Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty…
- Conditions
- Autism Spectrum Disorder, Restricted Behavior, Autism
- Trial name
- M-PRT-IS (NCT06362733)
- Testing
- Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism, Autism Spectrum Disorder
hCT-MSC in Children With Autism Spectrum Disorder
The purpose of this Phase II study is to determine the efficacy of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) for improving social communication abilities in children with autism spectrum disorder…
- Trial name
- IMPACT (NCT04089579)
- Testing
- Cord Tissue Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Joanne Kurtzberg, MD
Autism, Autism Spectrum Disorder
Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young…
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- PRT-HvC (NCT04899544)
- Testing
- Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C), Home-Based Pivotal Response Treatment (PRT Intervention (PRT-H)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorders
Susceptibility Genes in Autism Spectrum Disorders
The main objective of the study is to define, for Autism Spectrum Disorder, the extent of genetic variation in synaptic pathways that may be targeted for therapeutic development.
- Trial name
- NCT02628808
- Where
- 5 sites in France
- Volunteers
- 1,616 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder
A Placebo-controlled Trial of Folinic Acid in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and the presence of restricted or repetitive behaviors.
- Trial name
- AFAT (NCT07642661)
- Testing
- Folinic Acid
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Prof. Adi Aran