Clinical trials: Autoimmune Hyperthyroidism
Radioactive Iodine-Induced Hypothyroidism in Graves Disease Patients
Factors Affecting Timing of Hypothyroidism Following Radioactive Iodine Therapy Patients With Graves Disease
The purpose of this retrospective study was to clarify the possible risk factors of early hypothyroidism after RAI therapy in Graves' disease.
- Trial name
- NCT05643365
- Testing
- Radioactive Iodine therapy
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Graves Disease, Graves' Disease
Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease
The goal of this randomized pilot feasibility clinical trial is to determine the feasibility of implementing a protocol for a larger trial to assess the effects of high-dose vitamin D supplementation in pediatric patients (9-17…
- Conditions
- Graves Disease, Graves' Disease, Hyperthyroidism
- Trial name
- NCT07369063
- Testing
- Ergocalciferol 50,000 IU, Methimazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Type 1 Diabetes, Autoimmune Diseases
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up
This study aims to describe the prevalence of additional autoimmune diseases and their specific antibodies at type 1 diabetes (T1D) diagnosis, and their incidence rate during follow-up, for children and adolescents.
- Conditions
- Type 1 Diabetes, Autoimmune Diseases, Hashimoto Disease, Graves Disease
- Trial name
- AADT1D (NCT04789993)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Thyrotoxicosis
Thiamine Supplement in Patients With Severe Hyperthyroidism
Thyrotoxicosis is a hypermetabolic state in which there is increased utilization of thiamine. Thiamine deficiency has been observed in association with hyperthyroidism.
- Trial name
- NCT02767245
- Testing
- Thiamine
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Ramathibodi Hospital
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Graves Disease
Effect of Lugol's Solution in the Patients With Graves' Disease
Context: Although some of endocrine surgeons administer Lugol's solution to decrease thyroid gland vascularity, there is still no agreement on its effectiveness.
- Trial name
- NCT00432146
- Testing
- lugol's solution
- Volunteers
- 36 people
- Sponsor
- Istanbul University
Autoimmune Hyperthyroidism, Children
Autoimmune Hyperthyroidism in Prepubertal Children
The investigators propose a multicenter retrospective study to assess clinical, biochemical, and auxological characteristics at diagnosis and during follow-up in a cohort of Caucasian pediatric patients diagnosed with autoimmune…
- Trial name
- IPER6 (NCT07544290)
- Testing
- restrospective observational study
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Ospedale San Raffaele
Graves Disease
Effective Iodide Therapy for Untreated Patients With Graves' Hyperthyroidism Avoiding Thionamide Drugs With Many Side Effects
As the drug treatment of Graves' hyperthyroidism, Plummer reported the effectiveness of excess iodide in 1923 and iodide was used as the therapy for Graves' hyperthyroidism starting from the 1930s.
- Trial name
- NCT04686006
- Testing
- Potassium Iodide
- Volunteers
- 504 people
- Sponsor
- Kyushu University
Thyroid Associated Ophthalmopathy
Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid Associated Ophthalmopathy
The aim of the study is to compare the measurements of retinal nerve fiber layer (RNFL), macula and optical disc parameters obtained by optical coherence tomography (OCT), and intraocular pressure (IOP) between the patients with…
- Trial name
- NCT02766660
- Testing
- Optical Coherence Tomography
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Neon Hospital
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Hypothyroidism, Exophthalmos
The Prospective Study of Standard Treatment of Graves Disease Iodine 131 and Prevention of Adverse Reactions
Iodine 131 (131I） treatment on Graves disease and Graves ophthalmopathy relationship has always been the focus of debate. Majority view is that the current treatment does not increase 131I Graves ophthalmopathy, therefore,Graves…
- Trial name
- NCT01204359
- Testing
- Iodine 131
- Where
- 2 sites in China
- Volunteers
- 627 people
- Sponsor
- Sun Yat-sen University
Thyroid Disease, Autoimmune Hepatitis
Thyroid Disorders in Pediatric Autoimmune Hepatitis
This cross-sectional study aims to determine the frequency and spectrum of thyroid disorders among children with autoimmune hepatitis attending Assiut University Children's Hospital.
- Conditions
- Thyroid Disease, Autoimmune Hepatitis, Hashimoto Thyroiditis, Graves Disease
- Trial name
- NCT07827235
- Volunteers
- 32 people
- Sponsor
- Assiut University
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Thyroid Eye Disease
Evaluation of the Corneal Endothelial Cell Layer by Specular Microscopy in Patients With Thyroid Eye Disease
To investigate corneal endothelial cell layer damage by specular microscopy in patients with thyroid eye disease
- Trial name
- NCT06235372
- Testing
- Specular microscopy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bone Density, Low, Bone Mineral Density in Children With Graves' Disease
Bone Mineral Density in Children With Graves' Disease
to evaluate bone mineral density in children with graves' disease
- Trial name
- NCT06375096
- Testing
- evaluate bone mineral density
- Volunteers
- 100 people
- Sponsor
- Assiut University
Graves' Disease
TSH Receptor Antibody Heterogeneity in Children and Adolescents With Graves' Disease
Graves' disease, the most common form of hyperthyroidism in children, is caused by Thyrotropin (TSH) Receptor Antibodies (TRAbs) that mimic the action of TSH.
- Trial name
- NCT00335062
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Graves' Disease
Genetic Polymorphisms Associated With Cigarette Smoking and Risk of Graves' Disease
Cigarette smoking is a well-recognized risk factor of Graves' disease and, particularly, Graves' ophthalmopathy. Hence, germline polymorphisms of detoxification genes and genes belonging to the major DNA repair/apoptosis pathways…
- Trial name
- NCT00505011
- Volunteers
- 1,998 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Thyroid Diseases, Congenital Hypothyroidism
Prospective Evaluation of OptiThyDose
The aim of this multicentric, randomised, two-arms and single-blinded clinical trial is to prospectively evaluate OptiThyDose for Congenital hypothyroidism (CH) and Graves' disease (GD).
- Conditions
- Thyroid Diseases, Congenital Hypothyroidism, Graves Disease
- Trial name
- NCT06864351
- Testing
- OptiThyDose
- Where
- 7 sites in Armenia, France and 1 more
- Volunteers
- 150 people
- Sponsor
- University Children's Hospital Basel
Eye Diseases
Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease
In active phase of thyroid eye disease some patients have obvious upper lid retraction , and sometimes exposure keratopathy .To date there is not any standard treatment for this situation .
- Trial name
- NCT00370734
- Testing
- Botulinum toxin A injection
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Hashimoto Thyroiditis, Graves Disease
DNA Methylation and Autoimmune Thyroid Diseases
Hashimoto Thyroiditis (HT) and Graves Disease (GD) are known to be caused by abnormal immune response against self cells and tissues.
- Trial name
- THYRODNA (NCT02491567)
- Where
- Greece
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki