Clinical trials: Back Surgery
Adolescence Idiopathic Scoliosis, Preoperative Anxiety
the Effect of the Preoperative Information Method on Intraoperative Anxiety and Postoperative Outcomes in AIS Patients: a Randomized Clinical Trial
Due to the increasing use of smartphones and social media in contemporary times, adolescents experience a rapid loss of attention while reading or listening.
- Conditions
- Adolescence Idiopathic Scoliosis, Preoperative Anxiety, Postoperative Pain After Spinal Surgery
- Trial name
- NCT07902674
- Testing
- İntervention 1: Video-Based Preoperative Education, İntervention 2: Brochure-Based Preoperative Education, Routine Verbal Preoperative Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gazi University
Cerebral Palsy Spastic Diplegia, Gait, Spastic
The Effect of Selective Dorsal Rhizotomy Surgery on Walking in Children With Ambulatory Cerebral Palsy in Turkey
Cerebral Palsy (CP) is a motor disorder that develops during fetal brain development or due to non-progressive damage to the developing infant brain.
- Trial name
- NCT06617507
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Acıbadem Atunizade Hospital
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Intermediate Uveitis, Posterior Uveitis
Retisert and Cataract Surgery in Patients With Severe Uveitis
To review chart data at the Duke Eye Center and determined whether a 3-year fluocinolone acetonide sustained drug delivery system (FA) safely suppressed postoperative inflammation when combined with phacoemulsification and…
- Trial name
- NCT00570830
- Testing
- Retisert (fluocinolone acetonide implant)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Congenital Cataract, Aphakic Glaucoma
Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma
This is a retrospective, nonrandomized comparative trial with historical control to investigate the safety and efficacy of a novel progressive grasping peripheral iridectomy (PGPI) surgical method in preventing aphakic…
- Trial name
- NCT03610295
- Testing
- PPI group, cataract extraction
- Where
- 2 sites in China
- Volunteers
- 87 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Idiopathic Scoliosis
Skeletal Muscle and Adipose Tissue Study
The purpose of this research study is to compare the current standard of care for prophylactic Cefazolin administered every 3 hours intravenously with continuous infusion of Cefazolin during pediatric spinal surgery.
- Trial name
- NCT03190668
- Testing
- Bolus dose of Cefazolin, Continuous Cefazolin drip, Paraspinal muscle microdialysis catheters
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Scoliosis Idiopathic, Scoliosis; Adolescence
Postoperative Rehabilitation or Mobilization After Scoliosis Surgery
Scoliosis surgery is a major surgery associated with postoperative pain, loss of physical function and pulmonary dysfunction in adolescent idiopathic scoliosis patients (AIS).Despite the advanced, various medical treatment…
- Trial name
- NCT04403152
- Testing
- Post-operative rehabilitation, Post-operative mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Adolescent Idiopathic Scoliosis
Minimally Invasive Surgery vs Standard Posterior Approach in the Treatment of Developmental Idiopathic Scoliosis
This is a randomized trial with 1:1 allocation. The aim of the study is to evaluate clinical and radiographic outcomes in patients with developmental age idiopathic scoliosis treated with mini invasive scoliosis surgery (MIS)…
- Trial name
- NCT05860673
- Testing
- mini invasive scoliosis surgery, posterior spinal fusion technique
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cataract
Post-Implant Performance of the EC-3 IOL
The purpose of this study is to obtain data on the performance of the EC-3 lens at an interval of two years (and beyond) from subjects who were implanted.
- Trial name
- NCT01333345
- Where
- 3 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Aaren Scientific Inc.
Surgical Injury, Back Pain Lower Back Chronic
Spinal Approach for Lumbar Active Discopathy
The study aims to study the impact on different surgical approaches for lumbar active discopathy. This inflammatory disease of the disc and adjacent vertebral endplates can induce low back pain with inflammatory-like features.
- Trial name
- NCT04086199
- Testing
- Lumbar discectomy
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Idiopathic Scoliosis
Study of DDAVP Combined With TXA on the Blood Loss and Transfusion Need During and After Scoliosis Correction Surgery
Intraoperative administration of tranexamic acid (TXA,T) reduces significantly blood loss and blood transfusion requirements during spinal posterior fusion in adolescents with scoliosis.
- Trial name
- NCT02084342
- Testing
- tranexamic acid and sodium chloride injection, normal saline, desmopressin acetate injection
- Volunteers
- 60 people
- Sponsor
- Liu Weifeng
Glaucoma
5 Years Long Term Results After Standalone CyPass-Implantation
This study evaluates the results of all clinically relevant findings of glaucoma diagnostics 5 Years after stent-implantation concerning the safety and effectiveness of the cypass stent procedure.
- Trial name
- NCT03114059
- Testing
- Glaucoma diagnostics
- Where
- Germany
- Volunteers
- 230 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Scoliosis; Adolescence, Spine Fusion
Evaluation of Surgical Treatment of Idiopathic Scoliosis With Vertebral Body Tethering Versus Posterior Spinal Fusion.
The aim of this study is to evaluate the short, medium and long-term efficacy and safety of vertebral body tethering, based on the results obtained at 3-5 months of follow-up, exploring not only the ability to correct scoliosis…
- Trial name
- NCT07450326
- Testing
- gait analysis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Istituto Ortopedico Rizzoli
Neurectomy
Graft Reinforcement for Posterior Nasal Nerve Neurectomy in Allergic Rhinitis Surgeries
Rhinitis is defined clinically as having two or more symptoms of anterior or posterior rhinorrhea, sneezing, nasal blockage and/or itching of the nose during two or more consecutive days for more than 1 h on most days.
- Trial name
- NCT05880134
- Testing
- conventional posterior nerve neurectomy, cartilage graft reinforcement after posterior nerve neurectomy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Kafrelsheikh University
Postoperative Pain, Cryptorchidism
Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing…
- Trial name
- NCT07426796
- Testing
- Ultrasound-guided Posterior Quadratus Lumborum Block., Ultrasound-guided Quadroiliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medipol University
Posterior Spine Surgery
Kyphoscoliosis Surgery: Blood Conservation and Analgesia
Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications.
- Trial name
- NCT03319563
- Testing
- Local anesthetic-epinephrine, Saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Congenital Hemivertebra
Early Surgical Intervention of Congenital Hemivertebra in Young Children
Early treatment of congenital hemivertebrae is very important. The investigators design this study to figure out how early hemivertebrae resection be apply to children.
- Trial name
- NCT04527406
- Testing
- posterior hemivertebra resection, conservative treatment+ delayed posterior hemivertebra resection
- Sponsor
- Children's Hospital of Fudan University
Failed Back Surgery Syndrome, Spinal Stenosis
Value of Three-dimensional Rotational Epidurography on Percutaneous Epidural Adhesiolysis
Conventional epidurography (CE) is thought to have insufficient usefulness on percutaneous epidural adhesiolysis (PEA). The investigators aimed to evaluate the association between the outcome of PEA and three…
- Trial name
- NCT04216992
- Testing
- Cone beam computed tomography
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Postoperative Infection
The Effect of Prolonged Postoperative Antibiotics Administration on Rate of Infection in Patients Undergoing Posterior Spine Surgery Requiring a Hemovac Drain
Post-operative antibiotics for infection prophylaxis are routinely given to most surgical patients, and for orthopaedic surgery patients, the standard of care is treatment for 24 hours following any elective procedure (1).
- Trial name
- PARISS (NCT01458223)
- Testing
- Antibiotic
- Where
- Canada
- Volunteers
- 645 people
- Sponsor
- The London Spine Centre