Clinical trials: Bacteria
Healthy
Genomic Tools for Studying the Ecology of the Human Vaginal Microflora
The human vagina contains a large number of normal bacteria. These bacteria are important because provide protection against other bacteria that may cause disease.
- Trial name
- VM (NCT00576797)
- Where
- 3 sites in United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Gut Microbiome Development
Phages Dynamics and Influences During Human Gut Microbiome Establishment
Microbial communities are key components of human environment. Consequently, human gut microbiome have been extensively studied providing a better understanding of the relations between bacterial populations and host physiology.
- Trial name
- METAKIDS (NCT03296631)
- Testing
- collection of diapers with fresh stools
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Dental Caries
Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children.
The purpose of this study is to evaluate the efficacy of probiotic products on caries-associated salivary bacterial counts (Streptococcus mutans and Lactobacillus) and its effect on dental plaque accumulation in a group of…
- Trial name
- NCT02692625
- Testing
- (L. reuteri Prodentis®).
- Where
- Saudi Arabia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Obesity, Intestinal Bacteria Flora Disturbance
Study on Dietary Nutrition Intervention Techniques for Children Obesity
With the rapid development of society and economy, children's simple obesity is the rising in the world and has become a chronic disease which is one of the biggest public health challenges in the world.
- Conditions
- Obesity, Intestinal Bacteria Flora Disturbance, Body Weight
- Trial name
- NCT02539836
- Testing
- Dietary nutrition based on plant fermentation extract, MRI in quantifying liver fat with MRS
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Neonatal Sepsis
Use of Probiotics to Reduce Infections, Death and ESBL Colonisation
This study examines the effect of oral probiotic treatment to newborns on preventing hospitalizations, death and colonization with Extended-spectrum beta-lactamase-producing Gram negative bacteria.
- Trial name
- ProRIDE (NCT04172012)
- Testing
- Labinic (R) probiotic mixture
- Where
- Tanzania
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Haydom Lutheran Hospital
Oral Odor (Halitosis), The Study Want to Know if Site Specific Mouth Rinsing With Oral Mouth Disinfectants Can be Better Than Paonoral Mouth Rinsing
Comparing Site Specific Mouth Disinfection With Commercial Oral Mouth Rinse With Traditional Oral Maouth Disinfection
Objectives: To determine whether site-specific mouth rinsing with oral disinfectants can improve oral odor beyond the traditional panoral mouth disinfection with mouth rinses by targeting specifically oral malodor implicate…
- Trial name
- NCT02221193
- Testing
- traditional mouth rinsing and site-specific mouth rinsing (crossover)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Baha University
Juvenile Idiopathic Arthritis
Oral Health, Saliva Bacteria, and Disease Activity in Children With JIA: A Cross-Sectional Study.
The goal of this observational study is to learn about the relationship between disease activity and oral health status in children with juvenile idiopathic arthritis (JIA).
- Trial name
- JIA (NCT07799831)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Dental Caries in Children
Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash…
- Trial name
- NCT05623605
- Testing
- Moringa mouthwash, star anise mouthwash, Indian costus mouth wash
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahda University
Generalized Aggressive Periodontitis
Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.
Generalized aggressive periodontitis (GAP) is an inflammatory disease that causes the severe and rapid destruction of periodontal tissue.
- Trial name
- NCT03642353
- Testing
- Triclosan
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Diarrhea
Etiology of Diarrhea in Guinea-Bissau and in Finland
Diarrhoea is the leading cause of death in the world with 2.2 million deaths every year. The majority of deaths are among children in developing countries, but the travellers encounter the disease as well.
- Trial name
- NCT01269554
- Where
- 3 sites in Finland, Guinea-Bissau
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Black Stains
Investigating the Bactericidal Effect of Probiotics on Chromogenic Bacteria in Children An In Vivo and In Vitro Study
To investigate the bactericidal effect of probiotics (Streptococcus salivarius M18 and Lactobacillus reuteri) on two types of bacteria (Aggregatibacter actinomycetemcomitans and Actinomyces naeslundii) causing black stains of…
- Trial name
- NCT06834815
- Testing
- Probiotic with Prebiotic
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Feeding; Disorder, Nonorganic Origin, Calcium Disorder
Evaluation of the Effect of Palm Olein Free Formula on Intestinal Flora and Gastrointestinal Tolerance
Depending on recent studies in literature the investigators aimed to compare whether gastrointestinal tolerance differs between infants fed with palm olein containing or palm olein free formulas.
- Conditions
- Feeding; Disorder, Nonorganic Origin, Calcium Disorder, Intestinal Bacteria Flora Disturbance
- Trial name
- NCT03770143
- Testing
- Feeding with palm olein formula
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Crohn Disease
Bacteria & Inflammation in the Gut (BIG) Study
Exclusive Enteral Nutrition (EEN) is the liquid diet given to children with active Crohn's Disease (CD). EEN has previously been shown to induce changes in major bacterial metabolites and dominant bacterial species which are more…
- Trial name
- BIG (NCT02341248)
- Testing
- Exclusive Enteral Nutrition (EEN)
- Where
- 5 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Acute Gastroenteritis
Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis
The goal of this clinical trial is to test the effect of mothers' application of yogurt probiotic bacteria on relieving their young children's acute gastroenteritis in children had two to five years old.
- Trial name
- NCT06090708
- Testing
- yogurt with probiotic bacteria
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Appliance Complication
The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs).
- Trial name
- NCT04788550
- Testing
- Fluoridated toothpaste, fluoride varnish (5% sodium fluoride), CPP-ACP plus crème group
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Primary Hypertension
Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension
Children and adolescents with primary hypertension (high blood pressure without an underlying secondary cause) are at increased risk of cardiovascular disease in adulthood.
- Trial name
- NCT07236125
- Testing
- No active intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yelda Kasımoğlu
Black Stains
Effect of Herbal Toothpaste Versus Conventional One on Black Stains
Twenty eight children with black stains on their teeth were divided into 2 groups of toothpaste to assess their effect on parental satisfaction, recurrence rate of black stains and change in number of bacteria before and after…
- Trial name
- RCT (NCT06872827)
- Testing
- Herbal toothpaste
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Attention Deficit Hyperactivity Disorders, Caries, Dental
Salivary Bacteria and Oral Health Status in Children With ADHD
Attention deficit and hyperactivity (ADHD) affect 6% of school-aged children. Few studies reported higher prevalence of caries and restorations among children with ADHD. Methylphenidate is the drug of choice to treat ADHD.
- Conditions
- Attention Deficit Hyperactivity Disorders, Caries, Dental, Xerostomia
- Trial name
- ADHD (NCT00966394)
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Airborne Microorganisms, Particulate Matter (PM)
Clean Air for Everyone (CLAIRE): an Intervention Study to Reduce the Amount of Fine Particulate Matter and Microorganisms in Classroom Air
In this study, the investigators tested whether portable air cleaners can improve the air quality in primary school classrooms. Poor air quality can affect children's respiratory health and learning.
- Trial name
- CLAIRE (NCT07479420)
- Testing
- HEPA filter air cleaners, Ionization or plasma air cleaners
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lidwien Smit