Clinical trials: Baseline
Intellectual Disabilities
Reading Intervention for Children With Intellectual Disabilities Who Require Augmentative and Alternative Communication
The goal of this multiple single case study with multiple randomized baseline (with four starting points and 18 measurements across time) is to conduct a reading intervention for 40 children with intellectual disabilities who…
- Trial name
- NCT05709405
- Testing
- Reading intervention
- Where
- 2 sites in Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Neurogenic Detrusor Overactivity, Pediatric
A Clinical Study to Investigate How Solifenacin Fluid is Taken up, How Long it Stays in the Body and How Effective and Safe it is in Treating Children Aged From 6 Months to Less Than 5 Years With Symptoms of Neurogenic Detrusor Overactivity (NDO)
The purpose of this study was to evaluate long term efficacy and safety of treatment with solifenacin succinate (the study drug) in children with neurogenic detrusor overactivity after multiple dose administration.
- Trial name
- NCT01981954
- Testing
- Solifenacin succinate
- Where
- 8 sites in United States, Belgium and 4 more
- Volunteers
- 23 people
- Sponsor
- Astellas Pharma Europe B.V.
Concussion, Brain, Dynamic Vision Tests
A Comparison of Dynamic Vision Between College Athletes & Controls
The purpose of this study is to establish baseline reference values for tests of static and dynamic visual acuity and gaze stabilization in collegiate athletes and non-athletes, and to determine if there are differences in vision…
- Trial name
- NCT05819489
- Testing
- Dynamic Vision Testing
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
ACL Injury, Anterior Cruciate Ligament Injuries
Baseline ACL Injury Risk Screening and Normative Data
This is a prospective, observational cohort study aimed at establishing a database of normative biomechanics for healthy athletes and surveying these athletes for 12 months following baseline testing for the occurrence of new…
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
- Trial name
- NCT06635668
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Sanford Health
HIV Infections
A Comparison of Epivir Plus Crixivan Combined With Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
To evaluate the tolerance, and comparative virologic and immunologic effects of the two combination regimens.
- Trial name
- NCT00002369
- Testing
- Indinavir sulfate, Lamivudine, Stavudine
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 200 people
- Sponsor
- Bristol-Myers Squibb
HIV Infections
A Comparison of Two Anti-HIV Triple-Drug Combinations in HIV-Infected Patients
The purpose of this study is to compare the safety and effectiveness of two anti-HIV drug combinations when given to HIV-infected patients who have never been treated with anti-HIV drugs.
- Trial name
- NCT00002168
- Testing
- Indinavir sulfate, Lamivudine, Stavudine
- Where
- 13 sites in United States, Puerto Rico
- Volunteers
- 200 people
- Sponsor
- Bristol-Myers Squibb
Neurogenic Detrusor Overactivity
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC
- Trial name
- KANGUROO (NCT05491525)
- Testing
- Vibegron
- Where
- 38 sites in United States, Belgium and 14 more
- Volunteers
- 71 people
- Sponsor
- Urovant Sciences GmbH
Hearing Loss, Ear Diseases
Baseline Performance and Fitting Parameters for Sonova Products
The purpose of this study is to assess the effectiveness and optimization of various FDA approved products.
- Conditions
- Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
- Trial name
- NCT05859568
- Testing
- Pinna-located microphone, Pinna-simulated microphone algorithm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Advanced Bionics
Neurogenic Detrusor Overactivity
A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity
The purpose of this study was to investigate a medicine for the treatment of symptoms and complications of neurogenic detrusor overactivity (NDO) in children and adolescents.
- Trial name
- NCT01565694
- Testing
- Solifenacin succinate
- Where
- 21 sites in United States, Belgium and 8 more
- Volunteers
- 76 people
- Sponsor
- Astellas Pharma Europe B.V.
Post Traumatic Stress Symptoms, Preterm Infant
EMDR Therapy in Preterm-Born Infants With Post-Traumatic Stress Symptoms
This study examines a trauma-focused treatment for very young children who were born prematurely and developed post-traumatic stress related symptoms after medical care.
- Trial name
- EMDR-INFANTS (NCT07590778)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) storytelling method
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Tanja Holtackers
Competence
Live Supervision in Psychotherapy: Study Protocol for a Single Case Experimental Design Study (SCED)
Although clinical supervision is an essential part of psychotherapy training and development, the empirical evidence for effects on therapist competence and patient outcome is limited.
- Trial name
- NCT05612113
- Testing
- Live Supervision + Session Goal Formulation, Session Goal Formulation
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Karolinska Institutet
Retinoblastoma
Evaluation of MRI of the Pineal Gland in Retinoblastoma
Rationale: Currently baseline brain MRI (magnetic resonance imaging) with extended follow-up of pineal cysts is systematically performed in all new retinoblastoma (Rb) patients, because children with hereditary retinoblastoma…
- Trial name
- TRbFU (NCT06367569)
- Testing
- Screening for trilateral retinoblastoma with MRI
- Where
- Netherlands
- Volunteers
- 607 people
- Sponsor
- Amsterdam UMC, location VUmc
Congenital Heart Disease, Physical Inactivity
Exergame-Based Physical Activity Promotion for Children and Adolescents With Congenital Heart Disease
The goal of this clinical trial is to learn whether a Nintendo Switch-based exergame physical activity program can help children and adolescents with congenital heart disease increase their physical activity.
- Trial name
- ExPACE-CHD (NCT07593118)
- Testing
- Nintendo Switch-Based Exergame Physical Activity Promotion Intervention
- Where
- China
- Volunteers
- 13 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
X-Linked Adrenoleukodystrophy
A Study to Prospectively Assess Disease Progression in Male Children With X-ALD
This is a non-interventional, multi-center study that follows general principles of periodic assessment of X-ALD patients in routine practice.
- Trial name
- NCT03278899
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- NeuroVia, Inc.
Anorexia Nervosa, Anorexia in Adolescence
Emotional Dysregulation, Maladaptive Overcontrol in Anorexia - Effect of Radically Open Dialectical Behaviour Therapy
This clinical trial employs a two-fold approach, utilizing a single-arm feasibility design within a larger multiple baseline experimental case series study framework over 32 weeks.
- Conditions
- Anorexia Nervosa, Anorexia in Adolescence, Anorexia Nervosa, Atypical
- Trial name
- EMARO (NCT06244576)
- Testing
- Radically Open Dialectical Behaviour Therapy (RO-DBT)
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Umeå University
Idiopathic Short Stature
Predictive Value of the Insulin-like Growth Factor-1 (IGF-1) Generation Test for the Growth Response to Growth Hormone Treatment (PRED-IGF)
The evaluation of a standardized diagnostic test to predict the growth response in a 1 year trial with Growth Hormone (GH) treatment (carried out in the context of regular patient care) in non GH deficient short children with low…
- Trial name
- NCT01438801
- Testing
- Nutropin [Somatropin (rDNA origin) for injection]
- Sponsor
- Ipsen
Asthma
Observational Assessment of Baseline Asthma Control in African-American Children
To determine if baseline asthma control influences susceptibility to pollutant-induced health effects in African-American children with moderate-to-severe asthma.
- Trial name
- TeenAire (NCT01891630)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Hyperactivity Disorder (ADHD)
LearningRx Cognitive Training for ADHD
The purpose of this investigation is to conduct a series of case studies on the impact of LearningRx cognitive training on cognitive skills, brain structure, and daily functioning for participants with ADHD.
- Trial name
- NCT02917109
- Testing
- LearningRx cognitive training
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Gibson Institute of Cognitive Research
Patient Participation, Pediatric ALL
Inclusion Appeal Videos and Intent to Register for Pediatric Clinical Trials
An informational video about joining a Research Notification Registry is being compared with a version of the video tailored to African/ African American parents, reminding them about the importance of their being included in…
- Trial name
- NCT06138145
- Testing
- Video, Survey
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Renal Transplanted Recipients, Kidney Function
Renal Function Prediction in Living Donor Transplant Using Baseline Data
This study aims to predict early post-transplant kidney function in living donor kidney transplant recipients using baseline characteristics of donors and recipients.
- Trial name
- NCT06728995
- Where
- South Korea
- Volunteers
- 3,500 people
- Sponsor
- Seoul National University Hospital