Clinical trials: Baseline
Psychosis, Psychotic Disorders
Imagery Rescripting as a Treatment for Early Psychosis
The goal of this multiple baseline case series study is to test the effect of imagery rescripting (ImRs) in early psychosis. Primary objective :The course of schema or core beliefs, wellbeing and self-esteem in early psychosis.
- Conditions
- Psychosis, Psychotic Disorders, Schizophrenia, Psychoses, Traumatic
- Trial name
- NCT06539780
- Testing
- Imagery Rescripting
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Food Allergy, Eczema
The Cork BASELINE Birth Cohort Study
The Departments of Paediatrics and Child Health, Obstetrics/Gynaecology and Nutritional Sciences, University College Cork, and the Department of Dermatology, Trinity College, Dublin have a unique and urgent opportunity to form a…
- Conditions
- Food Allergy, Eczema, Obesity
- Trial name
- BASELINE (NCT01498965)
- Where
- Ireland
- Volunteers
- 2,185 people, healthy volunteers welcome
- Sponsor
- National Children's Research Centre, Ireland
Lymphoma
Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00049595
- Testing
- bleomycin sulfate, filgrastim, pegfilgrastim
- Where
- 140 sites in Australia, Belgium and 11 more
- Volunteers
- 552 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Malaria
Baseline Cohort Malaria Morbidity Study
The BLOOMy study is a longitudinal prospective cohort study of healthy children to assess the incidence of clinical malaria over the main transmission season.
- Trial name
- BLOOMy (NCT04601714)
- Where
- Burkina Faso
- Volunteers
- 459 people
- Sponsor
- Groupe de Recherche Action en Sante
Hemophilia
The Dynamic Interplay Between Bleeding Phenotype and Baseline Factor Level in Moderate and Mild Hemophilia A and B
There are large inter-individual differences in the bleeding pattern of patients with moderate or mild hemophilia. The major determinant of bleeding phenotype is the level of coagulant factor VIII or IX.
- Trial name
- DYNAMO (NCT03623295)
- Testing
- Blood sample, Questionnaire, MRI-imaging
- Where
- 17 sites in Australia, Austria and 8 more
- Volunteers
- 304 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Idiopathic Short Stature
Predictive Value of the Insulin-like Growth Factor-1 (IGF-1) Generation Test for the Growth Response to Growth Hormone Treatment (PRED-IGF)
The evaluation of a standardized diagnostic test to predict the growth response in a 1 year trial with Growth Hormone (GH) treatment (carried out in the context of regular patient care) in non GH deficient short children with low…
- Trial name
- NCT01438801
- Testing
- Nutropin [Somatropin (rDNA origin) for injection]
- Sponsor
- Ipsen
Congenital Muscular Torticollis
Perception-Action Approach Intervention for Infants With Congenital Muscular Torticollis
Infants with congenital muscular torticollis (CMT) display postural and functional asymmetry that interferes with their development.
- Trial name
- P-AA (NCT02907801)
- Testing
- Perception-Action Approach
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Stroke, Acute, Driving
Evaluating the Practice Resource for Driving After Stroke
After stroke, individuals must be assessed to determine if they can resume driving. Return to driving is very important to people who have experienced a stroke.
- Conditions
- Stroke, Acute, Driving, Occupational Therapy
- Trial name
- NCT06303765
- Testing
- Practice Resource for Driving After Stroke (PReDAS)
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Western University, Canada
Aging
PUER ("Previously Unrecognized Emerging Risks") Life Clinical Study (PUER) in Ages 6 Through 18
The goal of this observational study is to learn about changes in health in children that develop over time that may impact overall health and a healthy lifespan.
- Trial name
- NCT06802029
- Testing
- Whole Genome Sequencing Analysis
- Where
- United States
- Sponsor
- Puer Research, LLC
Metabolic Syndrome X
OPUS School Meal Study - Cross Sectional Analyses From Baseline Investigations
The present study is based on cross-sectional data from the baseline investigations carried out in OPUS School Meal Study - a randomized crossover study carried out in 9 primary schools in Denmark 2011-2012.
- Trial name
- NCT01577277
- Where
- Denmark
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Arne Astrup
Neuromyelitis Optica (NMO), NMO Spectrum Disorder (NMOSD)
Efficacy and Safety Study of Satralizumab (SA237) as Add-on Therapy to Treat Participants With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD)
The objective of this study is to evaluate the efficacy, safety, pharmacodynamic, pharmacokinetic, and immunogenic profiles of satralizumab, compared with placebo, in addition to baseline immunosuppressive treatment in…
- Trial name
- NCT02028884
- Testing
- Satralizumab, Baseline Treatment
- Where
- 40 sites in United States, France and 9 more
- Volunteers
- 85 people
- Sponsor
- Hoffmann-La Roche
Retinoblastoma
Evaluation of MRI of the Pineal Gland in Retinoblastoma
Rationale: Currently baseline brain MRI (magnetic resonance imaging) with extended follow-up of pineal cysts is systematically performed in all new retinoblastoma (Rb) patients, because children with hereditary retinoblastoma…
- Trial name
- TRbFU (NCT06367569)
- Testing
- Screening for trilateral retinoblastoma with MRI
- Where
- Netherlands
- Volunteers
- 607 people
- Sponsor
- Amsterdam UMC, location VUmc
Attention Deficit Hyperactivity Disorder (ADHD)
LearningRx Cognitive Training for ADHD
The purpose of this investigation is to conduct a series of case studies on the impact of LearningRx cognitive training on cognitive skills, brain structure, and daily functioning for participants with ADHD.
- Trial name
- NCT02917109
- Testing
- LearningRx cognitive training
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Gibson Institute of Cognitive Research
Phenylketonuria
Nutritional and Neurotransmitter Changes in PKU Subjects on BH4
HYPOTHESIS: The investigators hypothesize that KuvanTM therapy could influence nutritional and body composition parameters and neurotransmitter concentrations in pediatric and adult PKU subjects.
- Trial name
- BH4&PKU (NCT00688844)
- Testing
- KuvanTM Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Emory University
Epilepsy
Study to Evaluate a New Device Designed to Collect Heart Activity and Body Movement Data
This study is designed to collect data to support development of a novel product designed to sense changes in heart rate or movement during periods of sleep in people with epilepsy.
- Trial name
- NCT01626599
- Testing
- ProGuardian
- Where
- 6 sites in United States
- Volunteers
- 147 people
- Sponsor
- Cyberonics, Inc.
Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID)
Evaluation of Patients With Immune Function Abnormalities
This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation.
- Conditions
- Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID), Leukocyte Adhesion Deficiency 1 (LAD), Graft Versus Host Disease (cGvHD)
- Trial name
- NCT00128973
- Where
- United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Neurogenic Detrusor Overactivity
A Study to Learn How Effective and Safe the Drug 'Mirabegron' is and How Long it Stays in the Body of Children Aged 6 Months to Less Than 3 Years of Age With Neurogenic Detrusor Overactivity
People with neurogenic detrusor overactivity (NDO) have poor bladder control because of how their nerves to the bladder are wired. This can cause high pressure in the bladder, causing it to leak urine by accident (incontinence).
- Trial name
- NCT05621616
- Testing
- mirabegron
- Where
- 3 sites in Philippines, Poland
- Volunteers
- 7 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Spinal Cord Injury
Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury
Following spinal cord injury (SCI), the body loses normal control of blood pressure and heart rate, and there is a risk of sudden and dangerous increases in blood pressure, namely, autonomic dysreflexia (AD).
- Trial name
- NCT01599455
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Shriners Hospitals for Children
Children With a Need of Rehabilitation for Handwriting
Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO )
Difficulties in learning to write affect a large number of children and can have a significant impact on their personal and professional future.
- Trial name
- RVALIGO (NCT07040722)
- Testing
- Baseline, Intervention
- Where
- 5 sites in France
- Volunteers
- 12 people
- Sponsor
- Fondation Ildys