Clinical trials: Behavior Problem, open to volunteers
Substance Use Disorders, Criminal Behavior
Improving Outcomes in Social Services Through Routine Outcome Monitoring and Systematic Client Feedback
In this project the investigators want to test whether a new method FIT (Feedback informed treatment) can improve the interventions people receive through social services.
- Conditions
- Substance Use Disorders, Criminal Behavior, Domestic Violence, Social Care
- Trial name
- NCT07303608
- Testing
- Feedback informed treatment (FIT), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Child Behavior Problem, Preterm
I-InTERACT Preterm Parenting
Many children born very preterm experience behavior problems, and existing resources for parenting these children are lacking. A pilot trial established the effectiveness of a preterm parenting intervention, I-Interact Preterm…
- Conditions
- Child Behavior Problem, Preterm, Parent-Child Relations, Parenting
- Trial name
- I2P-RCT (NCT06767293)
- Testing
- I-InTERACT Parenting Intervention (I2P) and coaching sessions, I-InTERACT Parenting Microlearning Intervention (I2P Micro) and coaching sessions, Internet Resources
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cornelia de Lange Syndrome
Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome
The goals of this clinical trial are to identify factors associated with the development of problem behavior in Cornelia de Lange syndrome (CdLS) and to develop an effective behavioral assessment and treatment model for problem…
- Trial name
- NCT05829668
- Testing
- ABA-based functional analysis and treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Prader-Willi Syndrome
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
- Trial name
- NCT06366464
- Testing
- Pitolisant tablet
- Where
- 57 sites in United States, Australia and 11 more
- Volunteers
- 134 people
- Sponsor
- Harmony Biosciences Management, Inc.
Psychiatric Disorders, Insomnia
Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia
The goal of this investigator-initiated, randomized, blinded, 3-armed placebo-controlled, pragmatic, clinical superiority trial is to examine the efficacy of melatonin or low-dose quetiapine versus placebo for treatment of…
- Trial name
- MEL-QUE (NCT06062953)
- Testing
- Melatonin, Quetiapine
- Where
- Denmark
- Volunteers
- 255 people
- Sponsor
- Lone Baandrup
Mental Health Issue, Adolescent Behavior
Effectiveness of Promoting the Role of General Practitioners in a Mental Health Care System Integrated With Primary Care in Adolescence, According to the World Health Organization Definition
MG-integr-ADO aims to create and evaluate in France, a system of integrated mental health care in primary care for adolescents with mental illness.
- Trial name
- MGIntegrADO (NCT07186335)
- Testing
- self-questionnaire
- Volunteers
- 1,400 people
- Sponsor
- Fondation Santé des Étudiants de France
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Burnout, Professional, Stress, Psychological
The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers
The goal of this clinical trial is to learn if laughter yoga can improve both individual and organizational outcomes in nurse managers.
- Conditions
- Burnout, Professional, Stress, Psychological, Compassion Fatigue, Quality of Life
- Trial name
- NCT07235735
- Testing
- Laughter Yoga Program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cannabis Use, Cannabis Dependence
Neuroimaging of Adolescent Cannabis Use Treatment
This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use.
- Conditions
- Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse
- Trial name
- ACT (NCT07340554)
- Testing
- Contingency Management, Elastic Net Regression
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Mental Health Issue
Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs
The majority of children exposed to early adversity and trauma do not have access to sustainably delivered evidence-based mental health programs (EBPs), despite the growing prevalence of large-scale multiple-EBP implementation…
- Trial name
- SUPPORTS (NCT04712461)
- Testing
- SUPPORTS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Conduct Disorders in Children, Disruptive Behavior
Effects and Implementation of a Brief Version of Parent-Child Interaction Therapy
The aim of this study is to evaluate the effects and feasibility of a shortened version of Parent-Child Interaction Therapy (PCIT), supplemented with video vignettes of parenting skills and 360-virtual reality (VR)-films for…
- Conditions
- Conduct Disorders in Children, Disruptive Behavior, Oppositional Defiant Disorder
- Trial name
- NCT07201090
- Testing
- Brief Parent-Child Interaction Therapy with videos and virtual reality (360-degree VR)-films
- Where
- 2 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Karolinska Institutet
Adolescent Behavior Problem, Mental Health Wellness 1
Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program
The current study tests the feasibility and effectiveness of a youth intervention designed to provide meaningful leadership opportunities through the acquisition of leadership skills as well as mindfulness practice, LEAP…
- Trial name
- FLP (NCT06736522)
- Testing
- Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
- Where
- 3 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Mood Disorders, Anxiety Disorders
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
A 24-week, patient- and rater-blinded, two-arm, parallel-group controlled, and multi-centre randomized clinical trial (RCT) to establish the benefits of pharmacogenetics-informed pharmacotherapy versus dosing as usual (DAU) in…
- Conditions
- Mood Disorders, Anxiety Disorders, Psychotic Disorders
- Trial name
- PSY-PGx (NCT05656469)
- Testing
- Personalised medication advice based on pharmacogenetic testing
- Where
- 9 sites in United States, Germany and 5 more
- Volunteers
- 2,500 people
- Sponsor
- Parnassia Groep
Depression, Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
The goal of this parallel arm prospective randomized control trial study is to compare outcomes in Anterior Cruciate Ligament Reconstruction (ACLR) Surgery patients after exposure to a virtual psychological intervention (VPI)…
- Conditions
- Depression, Anterior Cruciate Ligament Injuries, Mental Health Issue
- Trial name
- NCT05965310
- Testing
- Virtual Psychological Intervention: Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Henry Ford Health System
Behavior Problems, Pediatrics
Postoperative Behavioral Changes in Children.
In children scheduled for dental treatment, negative thoughts can lead to anxiety and make them resistant to treatment techniques.
- Conditions
- Behavior Problems, Pediatrics, Pediatric Pain and Anxiety
- Trial name
- NCT06761833
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Baskent University
Problem Behavior, Aggression
Manualized Assessment and Treatment Model of Challenging Behavior
Despite decades of mounting single-case-design evidence for the efficacy of applied behavior analysis (ABA) and other approaches for the assessment and treatment of challenging behavior, an evidence-based comprehensive approach…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05928247
- Testing
- Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Serious Suicide Attempt
Associated Psychiatric Disorders in Children Hospitalized for a Serious Suicide Attempt
Several studies agree on the increase in suicide attempts in children over the past 15 years. This trend has been aggravated by the COVID 19 pandemic.
- Trial name
- SuiciDev (NCT05450354)
- Testing
- Questionnaires, Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris