Clinical trials: Behavioral
Tourette Disorder, Chronic Tic Disorder
Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Expert reviews and practice parameter papers recommend behavior therapy as a first-line intervention for youth with chronic tic disorders (CTDs) with mild-to-moderate tic severity.
- Trial name
- DCS+HRT (NCT02582515)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Schizophrenia / Schizoaffective Disorder
Validation and Comparative Multi-Omics Benchmarking of Fluid-Derived Volatilomics Biomarkers for the Prevention and Early Detection of Schizophrenia
Schizophrenia (SZ) is one of the most severe and costly mental disorders in terms of human suffering and societal expenditure. Currently, there are no biomarkers that facilitate the early diagnosis of SZ.
- Trial name
- MZvyagintsev (NCT07876089)
- Where
- Germany
- Volunteers
- 3,692 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Active, Symptomatic Blepharitis
Comparative Study to Evaluate ISV-305 Compared to Vehicle in Blepharitis Subjects
The purpose of this study is to evaluate the clinical efficacy and safety of ISV-305 (Dexamethasone in DuraSite® 2) compared to Vehicle in the treatment of subjects with active, symptomatic Blepharitis.
- Trial name
- ISV-305 (NCT01543490)
- Testing
- ISV-305, Vehicle
- Where
- United States
- Volunteers
- 558 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Trachoma
Impact of Water and Health Education Programs on Trachoma and Ocular C. Trachomatis in Niger
There are no specific trials addressing the benefit of water provision and health education on prevalence of trachoma and infection with ocular Chlamydia trachomatis over time, despite considerable effort to provide water…
- Trial name
- NCT00348478
- Testing
- water and health education program to improve hygiene
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Infant, Low Birth Weight
Post Discharge Human Milk Fortifier in Preterm Infants
The purpose of this study is to determine whether low birth weight (LBW) infants fed human milk (HM)supplemented with a specially designed powdered human milk fortifier until 12 weeks after hospital discharge will have better…
- Trial name
- NCT00413985
- Testing
- Nutrient-enriched human milk
- Where
- 9 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Head Injury
Effect of Rosuvastatin on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Moderate Head Injury
The purpose of this study is to determine whether rosuvastatin is effective in the management of moderate head injury by improving amnesia and orientation.
- Trial name
- NCT00329758
- Testing
- rosuvastatin
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Obesity, Overweight
Growing Resilience in Wind River Indian Reservation
The Growing Resilience research leverages reservation-based assets of land, family, culture, and front-line tribal health organizations to develop and evaluate home food gardens as a family-based health promotion intervention to…
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- GR (NCT02672748)
- Testing
- Garden
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Aromatherapy, Test Anxiety
The Effect Of Aromatherapy Applied To Children Aged 9-12 On Exam Anxiety, Attention Deficit and Academic Success
This study was planned to examine the effects of aromatherapy applied to children aged 9-12 on exam anxiety, attention deficit and academic success. The study was conducted as single blind.
- Conditions
- Aromatherapy, Test Anxiety, Attention Deficits, Academic Achievement
- Trial name
- NCT06791785
- Testing
- Before Application, Before the 1st Written Exam, End of Term
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Substance Use Disorder (SUD)
The Effect of Cognitive Behavioral Model-Based Psychoeducation on Social Exclusion, Hopelessness, and Relapse Levels in Individuals Diagnosed With Substance Use Disorder
This research was planned to measure the effect of cognitive behavioral model-based psychoeducation on the level of social exclusion and hope in individuals diagnosed with substance use disorder, as well as teaching them to cope…
- Trial name
- NCT07316335
- Testing
- Cognitive Behavioral Therapy (CBT) Theoretical Basic Training Group
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Health Behavior
Personalized Recommendation System for Sport Activities
The goal of this clinical trial is to test and compare the effects of a tailored algorithm recommendation of sport activities concreted in challenges to improve some critical performance dimensions.
- Trial name
- NCT06200350
- Testing
- Experimental group, Control group
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Breast Milk Collection, Human Milk/Breastfeeding
Human Milk and Its Effect on Infant's Metabolism and Infant Gut Microbiome
This protocol explains the MAINHEALTH cohort. The study examine the influence of maternal health parameters on human breast milk composition and integrates milk phenotype with infant metabolism and infant gut microbial content…
- Conditions
- Breast Milk Collection, Human Milk/Breastfeeding, Human Milk Microbiome, Infant Gut Microbiome
- Trial name
- MAINHEALTH (NCT05111990)
- Where
- Denmark
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression
Cognition and Behavior With Sham Accelerated TMS
The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards.
- Trial name
- NCT07397858
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Healthy
Impact of Move to Clinical Research Center on Physical Activity of Employees
This study will examine the changes that the move from NIH's Building 10 Clinical Center (CC) into the Clinical Research Center (CRC) may have on the amount of activity a person engages in daily, as registered by a pedometer…
- Trial name
- NCT00095485
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Reproductive Physiological Phenomena
Link Between the Sensitivity of Kisspeptin Signalling and Pubertal Onset in Boys.
The specific objective of this study was to investigate the sensitivity of Kisspeptin receptor 1 (KISS1R) by determining the responsiveness of GnRH neuron to kisspeptin administration across the pubertal stages and adult group…
- Trial name
- NCT03286517
- Testing
- Kisspeptin-10 (metastin 45-54, Calbiochem, Darmstadt, Germany)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ghulam Nabi
Depression, Acute Kidney Injury
Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
The purpose of this study is to determine if there is an excess risk of acute kidney injury (AKI) with Serotonin-norepinephrine reuptake inhibitors (SNRIs) as compared to Selective serotonin reuptake inhibitors (SSRIs), two…
- Trial name
- SNRI-AKI (NCT02320240)
- Testing
- Duloxetine, Venlafaxine, Desvenlafaxine
- Where
- Canada
- Volunteers
- 3,255,526 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Attention Deficit Hyerpactivity Disorder
ADHD Remote Technology and ADHD Transition: Predicting and Preventing Negative Outcomes
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition affecting 5.9% of young people. Late adolescence can be a particularly challenging period for young people with ADHD, with major life…
- Trial name
- ART-transition (NCT07228650)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College London
Adolescent - Emotional Problem, Adolescent Problem Behavior
Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design
In this pilot study, the effect of a group intervention targeting self-criticism in adolescents in a clinical child- and adolescent psychiatric outpatient setting will be examined using a single-case experimental design (AB).
- Conditions
- Adolescent - Emotional Problem, Adolescent Problem Behavior, Nonsuicidal Self Injury, Depressive Symptoms
- Trial name
- NCT05247190
- Testing
- Treating self-criticism
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Region Östergötland
Autism, Autism Spectrum Disorder
Work Chat: An Interactive Virtual Workday
Nearly 50,000 youth with autism spectrum disorder (ASD) transition from high school to adult life each year with only 25% of these transition-age youth with ASD (TAY-ASD) getting jobs within 2 years of graduation.
- Trial name
- NCT05565482
- Testing
- Work Chat: An Interactive Virtual Workday
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Surgical Residency, Workplace Culture
The Surgical Education Culture Optimization Through Targeted Interventions Based on National Comparative Data - "The SECOND Trial"
Due to a number of factors, residents are susceptible to mistreatment (i.e., discrimination, harassment, and abuse) and toxic outcomes (i.e., burnout, attrition, and suicidality).
- Conditions
- Surgical Residency, Workplace Culture, Mistreatment, Burnout
- Trial name
- SECOND (NCT03739723)
- Testing
- Resource allocation to improve surgical learning environments
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Indiana University
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