Clinical trials: Benchmark, open to volunteers
Neurofibromatosis Type 1
Gait in Young Children With NF1
The objective of this study is to develop office-based tools to quantify gait in young children with NF1 that reflect overall gross motor impairment and predict future gross motor difficulties.
- Trial name
- NCT07564622
- Volunteers
- 56 people
- Sponsor
- NYU Langone Health
Alexander Disease
Evaluation of Outcome Metrics in Alexander Disease
The purpose of this study is to define the natural history of Alexander Disease, a leukodystrophy that causes neurological dysfunction.
- Trial name
- AxD Outcomes (NCT02714764)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Philadelphia
Severe Aortic Valve Stenosis
In-vitro Benchmarking of Currently Available Heart Valve Prostheses for Surgical and Percutaneous Treatment of Aortic Stenosis With Small Annulus, Followed by In-vivo Validation
The general objective of this study is to compare in vitro and in vivo the hemodynamic performance of different types of aortic valve prostheses and possible surgical implantation techniques.
- Trial name
- SurPASS (NCT06859255)
- Testing
- MRI
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Diabetes Mellitus, Type 1
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
The goal of this clinical trial is to determine if transitioning to automated insulin delivery (AID) systems, can improve objectively measured sleep quality and quantity and alleviate cardiovascular risk factors in both children…
- Trial name
- AID-BEYOND (NCT06469593)
- Testing
- Automated insuling delivery system
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Steno Diabetes Center Copenhagen
Athletes, Soccer
Relationship of Anthropometric Profile and Fitness Indicators With Sports Performance of Elite Mexican National Team Soccer Players
Relating Anthropometric Profile to Fitness and Sports Performance in Mexican National Team Soccer Players
- Trial name
- ANTHROPERFORMX (NCT06941064)
- Testing
- Anthropometric and sports performance assessment
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Iberoamerican Institute of Sports Science and Human Movement
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Malnutrition (Calorie), Infant Nutrition Disorder
Goat Milk-Derived Formula vs. Undiluted Goat Milk in Infants Unable to Exclusively Breastfeed: Growth and Biomarker Analysis
The goal of this clinical trial is to learn if Goat Milk-Derived Formula Alternatives (GMDFA) are safe and effective for infants who are unable to be exclusively breastfed.
- Conditions
- Malnutrition (Calorie), Infant Nutrition Disorder, Growth Flatering, Gut Microbiome
- Trial name
- GMDFA (NCT07225153)
- Testing
- GMDFA, Undiluted Goat Milk
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Aga Khan University
Severe Traumatic Brain Injury
Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics
Narrative: Worldwide, traumatic brain injury (TBI) is a leading cause of death and disability among children and adolescents. The Investigators aim to test whether pediatric TBI treatment guided by invasive intracranial pressure…
- Trial name
- BELA TRIPP (NCT05566431)
- Testing
- ICP, CREVICE
- Where
- 11 sites in United States, Colombia and 4 more
- Volunteers
- 428 people
- Sponsor
- University of Washington
Cerebral Palsy (CP)
Wearable Eye Tracking During Bimanual Tasks in Children With Cerebral Palsy
This observational pilot study will include 40 children and adolescents aged 6 to 12 years: 20 with cerebral palsy and 20 with typical development.
- Trial name
- NCT07806994
- Testing
- Wearable Eye-Tracking Assessment During Structured Bimanual Tasks
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Type 1 Diabetes Mellitus
Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes
Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verapamil is an L-type calcium channel blocker that has been used for decades to treat hypertension and…
- Trial name
- NCT07804849
- Testing
- Verapamil oral
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Cardiovascular Diseases (CVD)
Swiss Secondary Prevention and Rehabilitation Registry
The SwissPR study is to continuously monitor patient characteristics and short- and long-term benchmark quality measures and outcomes of patients participating in a 12-week ambulatory CR program.
- Trial name
- SwissPR (NCT05500859)
- Testing
- Data collection at Baseline, 3 months after baseline (BL), 1-year follow-up, Telephone follow-up and questionnaire 3 years and 5 years after BL
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Lymphoma, Lymphoma, B-Cell
Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)
The purpose of this study is to find out if there is a benefit to giving rituximab with etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin (R-EPOCH) in participants who have high-risk B-cell PTLD in their 2nd…
- Trial name
- NCT06954805
- Testing
- Rituximab, Etoposide, Prednisone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Jennifer Amengual
Type1diabetes
Adherence to Mediterranean Diet in Type 1 Diabetes Initiating Minimed 780G: Glucose Metrics vs Insulin Metrics, is There a Difference
In this observaltional study, 240 patients aged >12 years old with T1DM who are on multiple daily injections or insulin pump and are scheduled to start using MiniMed 780G system will be included.We aim to compare patients'…
- Trial name
- NCT06646107
- Testing
- MInimed 780G
- Where
- Greece
- Volunteers
- 240 people
- Sponsor
- Attikon Hospital