Clinical trials: Biodentine
Pulp Exposure, Dental, Pulp Disease, Dental
The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This study employs saliva-based DNA analysis to investigate the effect of genetic polymorphisms, particularly SNPs in MMP, TIMP, TNF-α, and BMP genes, on the success of vital pulp therapy in permanent teeth with pulpitis…
- Conditions
- Pulp Exposure, Dental, Pulp Disease, Dental, Pulp Caping, Pulpitis
- Trial name
- NCT07130214
- Testing
- Biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ataturk University
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Discoloration
Tooth Discoloration Induced by Pulpotomy Materials
Vital pulp therapy including pulpotomy is commonly used for managing teeth with carious pulp exposure instead of performing root canal therapy.
- Trial name
- NCT04346849
- Testing
- Pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Symptomatic Irreversible Pulpitis, Symptomatic Irreversible Pulpitis (SIP)
Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy
This study evaluates treatment options for children and young adults with severe toothache in a permanent molar caused by symptomatic irreversible pulpitis.
- Trial name
- NCT07290049
- Testing
- Calcium Silicate Cement, Er,Cr:YSGG Laser
- Where
- United Arab Emirates
- Volunteers
- 46 people
- Sponsor
- University of Fujairah
Deep Dental Caries
Randomized Clinical Trial for Primary Molar Pulpotomy, Biodentine Vs Formocresol-ZOE
This is a RCT that will compare the clinical and radiographic success of pulpotomies on primary molars between the traditional technique (Formocresol/ZOE) and the new technique with Biodentine.
- Trial name
- NCT02201498
- Testing
- Pulpotomies with Formocresol/OZE and Biodentine
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Dental Restoration, Permanent, Dental Restorations
Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.
The aim of this present study is to collect additional data for the post-marketing follow-up of Biodentine™ XP and measure long-term (up to 10 years) performance and safety of the biomaterial in all its indications.
- Conditions
- Dental Restoration, Permanent, Dental Restorations, Endodontic Treatment
- Trial name
- BIOD XP (NCT06955429)
- Testing
- Dental restorative or endodontic treatment requiring Biodentine XP use
- Where
- 8 sites in Belgium, France
- Volunteers
- 275 people
- Sponsor
- Septodont
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Carious Exposure of Pulp
New Vital Pulpotomy Medications in Primary Molars
Evaluate clinically and radiographically the effect of biodentine and hyaluronic acid (HA) versus formocresol (FC) as pulpotomy medications in primary molars.
- Trial name
- NCT05937100
- Testing
- Formocresol, Biodentine, Hyaluronic acid gel
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulp and Periapical Tissue Disease
Regenerative Endodontics for Non-vital Primary Molars
Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold
- Trial name
- NCT05098483
- Testing
- Regeneration in primary molars by using MTA, Regeneration in primary molars by using biodentine, Conventional Root canal treatment in primary molars
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Endodontically Treated Teeth
Long-term Performance and Safety of Biodentine™ in Patients Treated for Endodontic Indications
In this observational, retro-prospective, and multicenter PMCF clinical investigation, Biodentine™, an active dentine substitute for professional dental use only, is evaluated at 10 years post-treatment, in its endodontic…
- Trial name
- NCT05084742
- Testing
- Biodentine™
- Where
- 6 sites in France
- Volunteers
- 145 people
- Sponsor
- Septodont
Reversible Pulpitis
The Role of Matrix Metalloproteinases on the Primary Teeth Pulpotomy Treatments
Matrix metalloproteinases (MMPs) are important zinc enzyme group that responsible for reducing extracellular matrix components. It has been reported that MMPs play an important role in pulpal inflammation.
- Trial name
- NCT05145686
- Testing
- Matris metalloproteinase -2, -8, -9 expressions
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ege University
Extensive Decay in Primary Molars
Biodentine Versus White MTA Pulpotomy
A clinical trial to evaluate and compare three different products used for endodontic treatment (taking the infected nerve out of the teeth) of primary teeth.
- Trial name
- NCT01733420
- Testing
- Biodentine pulpotomy, White MTA pulpotomy, Tempophore pulpotomy
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Ghent
Tooth Injuries
Comparison of Sealing Ability of MTA and Biodentine for Repairing of Furcal Perforation in Primary Molars
Preservation of the primary teeth is a mandatory issue for maintaining the integrity of the normal dentition and functioning till the eruption of the successors.
- Trial name
- NCT05006755
- Testing
- Mineral Trioxide Aggregate, Biodentine
- Volunteers
- 42 people
- Sponsor
- Amany hasanean Abd El sadek
Pulp Exposure, Dental
Biodentine Vital Pulpotomy in Immature Molars
This study aimed to evaluate the clinical and radiographic success of pulpotomy in cariously exposed vital immature first permanent molars using calcium hydroxide and calcium silicate-based material (Biodentine ™).
- Trial name
- NCT04989036
- Testing
- pulpotomy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpotomy, Dental Caries
Comparison of Biodentine and MTA Pulpotomies in the Primary Molar Teeth 3 Year Follow up
The aim of this study is to compare two pulpotomy medicaments in primary molars clinically.A total of 200 primary molars with deep caries were treated with two different pulpotomy medicaments (Mineral Trioxide Aggregate and…
- Trial name
- NCT03395496
- Testing
- Biodentine, ProRoot (Aggregate)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries
Biodentine Pulpotomy vs Metapex Pulpectomy in Primary Molars: Clinical & Radiographic Comparison of Outcomes in Irreversible Pulpitis Cases
Irreversible pulpitis is defined as a clinical diagnostic based on subjective and objective findings suggesting that the vital inflamed pulp is incapable of healing in the American Association of Endodontists (AAE) Consensus…
- Trial name
- NCT06524921
- Testing
- dental pulpectomy using metapex, dental pulpotomy using biodentine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mohamed Ahmed Hamdi Abo El Yamin
Pulp Disease, Dental
Clinical and Radiographic Evaluation of Biodentine Versus Formocresol
Aim of the study: To compare Formocresol and Biodentine clinically and radiographically when used for pulpotomy of primary molars Study Design : A randomized control clinical trial (split mouth and double blind) was conducted on…
- Trial name
- NCT03582319
- Testing
- Biodentine, Formocresol
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Cairo University
Infected Pulp, Root Canal Treatment
Evaluation Of Different Pulpotomy Agents Used For Treatment Of Immature Molars
The management of permanent teeth with incomplete root development with compromised pulpal integrity presents a unique challenge.
- Trial name
- NCT05347160
- Testing
- Biodentine
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mansoura University