Clinical trials: Biopsy, Fine-needle
Klatskin Tumor, Cholangiocarcinoma
Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
This is an observational study with a prospective cohort design. This study enrolled patients with suspected hilar cholangiocarcinoma on imaging.
- Conditions
- Klatskin Tumor, Cholangiocarcinoma, Biopsy, Fine-Needle, Endoscopic Retrograde Cholangiopancreatography
- Trial name
- NCT05993429
- Testing
- The sampling method selected in patients with suspected hilar cholangiocarcinoma
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qilu Hospital of Shandong University
Diagnoses Disease
Atypia of Undetermined Significance (AUS) / Follicular Lesion of Undetermined Significance (FLUS)
According to the guidelines for reporting thyroid fine needle aspirations known as The Bethesda System, the category of atypical cells known as AUS/ FLUS category has an estimated rate of 5 to 15% for malignancy.
- Trial name
- NCT03224754
- Testing
- Determination of risk of malignancy of these thyroid lesions
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Focus: Breast Cancer With Axillary Node Metastasis
Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy
The study was performed to determine if either ultrasound guided core biopsy or fine needle aspiration of an axillary lymph node has superior sensitivity in detecting metastatic carcinoma from the ipsilateral breast.
- Trial name
- NCT01920139
- Testing
- Fine needle aspiration and core biopsy of lymph node, Axillary surgery, Titanium marker
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Pittsburgh
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer
Studies on Tumors of the Thyroid
Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid…
- Conditions
- Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer
- Trial name
- NCT00001160
- Testing
- 68-Gallium Dotatate
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Thyroid Nodule
Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules
The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.
- Trial name
- NCT00571090
- Testing
- Thyroid ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 735 people
- Sponsor
- Istanbul Science University
Fine Needle Aspiration Cytology, Thyroid Diseases
Accuracy of FNAC in Thyroid Nodules Compared to to Surgical Specimen : QOC Experience
Thyroid gland diseases are the second most common endocrine disease following diabetes mellitus(1). Thyroid nodules are common disorders with a prevalence ranged from 4 to 7% in adult population, 5%-30% are malignant…
- Trial name
- Thyroid FNAC (NCT05521594)
- Testing
- Fine Needle Aspiration Cytology
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Qena Oncology Center
Endometrial Hyperplasia
Comparison of Dilatation & Curettage and Endometrial Aspiration Biopsy Accuracy in Patients Treated With Progestin for Endometrial Hyperplasia: A Korean Gynecologic Oncology Group Study
A prospective multicenter trial has been started in Korea to evaluate the diagnostic accuracy of endometrial aspiration biopsy compared with D\&C in patients treated with progestin for endometrial hyperplasia (EH).
- Trial name
- NCT02412072
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Korean Gynecologic Oncology Group
Endometrial Cancer
Compare the Performance of Targeted Biopsy Versus Aspiration Biopsy With a Pipette for the Diagnosis of Endometrial Cancer
Endometrial cancer is the most common pelvic gynecological cancer in so-called developed countries, with 320,000 new cases annually, including more than 1,500 in Belgium. It preferentially affects postmenopausal women.
- Trial name
- NCT03115593
- Testing
- Blind biopsy with a pipette, Targeted biopsy using hysteroscopy
- Where
- 4 sites in Belgium, France
- Sponsor
- Brugmann University Hospital
Breast Cancer
The Accuracy of Sentinel Node Biopsy of Breast Cancer With Sonographic Abnormal Axillary Lymph Nodes
This is a phase II, prospective, single-center, non-randomized, non-controlled study. Sentinel lymph node biopsy (SNB) is a standard staging procedure in early breast cancer.
- Trial name
- NCT02005926
- Testing
- Wire-localized abnormal node
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tao OUYANG
Thyroid Carcinoma, Thyroid Papillary Carcinoma
Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
In the last decades, thyroid cancer incidence has continuously increased all over the world, almost exclusively due to a sharp rise in the incidence of the papillary histologic subtype, which has the highest incidence of…
- Conditions
- Thyroid Carcinoma, Thyroid Papillary Carcinoma, Multinodular Goiter, Adolescent, Solitary Thyroid Nodule
- Trial name
- NCT04411290
- Testing
- Total thyroidectomy (TT)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Breast Cancer, Breast Neoplasms
A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer
This is a pilot, chemoprevention study. Patients receive fenretinide daily for 25 of every 28 days for 4 months and tamoxifen daily for 23 months, beginning the second month of fenretinide.
- Trial name
- NCT00001378
- Testing
- fenretinide
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer
Comparison Between Base and Cover Slide From Endoscopic Ultrasound Guided Fine Needle Aspiration for Pancreatic Cancer
The purpose of this study is to determine whether there is a difference of diagnostic accuracy between cover slides and base slides from EUS-FNA cytopathologic sample in patients who were previously suspected of pancreatic cancer…
- Trial name
- EUS-FNA (NCT02190071)
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Seoul National University Hospital
Hepatocellular Carcinoma
Primary Culture of Residual Specimens Obtained From Aspiration of Hepatic Tumor to Predict the Prognosis of the Patients
The aim of this project is to investigate whether the proliferative speeds of cultured cells using our method can be integrated into Barcelona Clinic Liver Cancer (BCLC) staging classification for the possibility of personalized…
- Trial name
- NCT02587793
- Testing
- not interventional study
- Where
- 2 sites in Taiwan
- Volunteers
- 208 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Solid Tumor
EUS-FNA for Patients With Antithrombotic Agents
The purpose of this study to evaluate a safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for patients with antithrombotic agents.
- Trial name
- NCT01798654
- Where
- Japan
- Volunteers
- 84 people
- Sponsor
- Hokkaido Pancreatobiliary Endoscopic Intervention Study Group
Pancreatic Neoplasm, Pancreatic Cyst
Percutaneous Versus EUS FNAC in Pancreatic Masses
We aim to evaluate the role of Ultrasound-guided (USG) fine needle aspiration cytology (FNAC) in diagnosis of pancreatic masses compared to endoscopic ultrasound (EUS) guided fine needle aspiration cytology (FNAC).
- Conditions
- Pancreatic Neoplasm, Pancreatic Cyst, Pancreatic Abscess
- Trial name
- NCT04623749
- Testing
- US, EUS
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ola Kamal Mohammed Galal
Suspicious for Papillary Thyroid Carcinoma
Role of Cytomorphometry and BRAFV600E Immunocytochemistry With a Cytologic Diagnosis "Suspicious for Papillary Thyroid Carcinoma"
Thyroid nodules (TNs) are a common finding, detected by ultrasound in about 70% of healthy individuals, with women being four times more affected.
- Trial name
- NCT06901908
- Volunteers
- 45 people
- Sponsor
- Assiut University
Biopsy, Needle
Comparing the Diagnostic Adequacy of 25-gauge Fork-tip, Franseen and Reverse-bevel Type Needles in Endoscopic Ultrasound Guided Tissue Acquisition
Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) and fine needle biopsy (EUS-FNB) are well established techniques for the acquisition of tissue to classify a number of lesions of the gastrointestinal tract and…
- Trial name
- NCT05434247
- Testing
- Needle choice
- Where
- Australia
- Volunteers
- 178 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Parotid Tumor
MRI and Fine Needle Aspiration in the Diagnosis of Parotid Tumors
What value is given to MRI diffusion and perfusion sequences in the diagnosis of parotid tumors? Is a fine needle aspiration associated with MRI systematically necessary? The aim of the research is to study the performance of…
- Trial name
- Parotid (NCT05152056)
- Where
- France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer
Modulation of Breast Cancer Risk Biomarkers by High Dose Vitamin D
The overall goal of this project is to determine if high dose vitamin D3 given to premenopausal women at high risk for development of breast cancer, who initially have insufficient levels of 25-hydroxy vitamin D (<30 ng/ml), will…
- Trial name
- NCT01166763
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carol Fabian, MD
Lung Cancer
Computed Tomography (CT) Guided Lung Biopsy: Core or Fine Needle Aspiration
This study is a comparison of core needle biopsy with fine needle aspiration biopsy in the evaluation of lung nodules.
- Trial name
- NCT00188526
- Testing
- lung biopsy
- Where
- Canada
- Sponsor
- University Health Network, Toronto