Clinical trials: Birth Control
Vaginal Delivery, Normal Labor
Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and…
- Trial name
- SSSA (NCT06823349)
- Testing
- Dexmedetomidine, fentanyl, Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jehan George Sadek
Staphylococcal Sepsis
Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis
Evaluate the safety, PK and efficacy comparing Pagibaximab Injection to placebo in preventing staphylococcal sepsis in very low birth weight infants.
- Trial name
- NCT00646399
- Testing
- Pagibaximab 50 mg/mL
- Where
- United States
- Volunteers
- 1,579 people, healthy volunteers welcome
- Sponsor
- Biosynexus Incorporated
Preterm Birth Complication, Digestive System Disease
Impact Assessment of Abdominal Massage on Feeding Tolerance of Preterms
Every year in France, 60,000 children are born prematurely (before 37 weeks of amenorrhea - WA), and present an immaturity of their various systems, in particular the digestive system.
- Trial name
- PREMABDO (NCT06351202)
- Testing
- Abdominal massage
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Preterm Infant, Sleep
Circadian-Synchronized Breast Milk Feeding and Sleep in Preterm Infants: A Multicenter Randomized Controlled Trial
This clinical trial aims to find out whether a circadian-synchronized breast milk feeding approach can help improve sleep in preterm infants in the neonatal intensive care unit (NICU).
- Trial name
- NCT07645677
- Testing
- Circadian-Synchronized Breast Milk Feeding, Routine Breast Milk Feeding
- Where
- 6 sites in China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Unintended Pregnancy, Teen Births
The Contraceptive Choice Project
The purpose of this project is to remove barriers to obtaining contraceptive methods, including the most effective and expensive methods.
- Conditions
- Unintended Pregnancy, Teen Births, Abortion, Contraception
- Trial name
- NCT01986439
- Where
- United States
- Volunteers
- 9,256 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy, Prematurity
Best Practices Fo Early Diagnosis of Cerebral Palsy
In this research, the investigators are using an implementation science approach to enhance the uptake of a clinical practice guideline for earlier diagnosis of cerebral palsy (i.e.
- Trial name
- CP (NCT06537622)
- Testing
- Implementation group, Standard of care
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Premature Birth
Iron-fortified Parenteral Nutrition in the Prevention and Treatment of Anemia in Premature Infants
The purpose of this study is to determine whether iron-fortified PN is effective in the preventative and treatment of preterm infants. Preterm infants are at risk for anemia especially in preterm infants.
- Trial name
- NCT02743572
- Testing
- iron sucrose-1, iron sucrose-2, iron sucrose-3
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Severe Malaria, Severe Anaemia
Post-discharge Malaria Chemoprevention Implementation Trial in Benin
The proposed research aims to conduct implementation trials in Benin, co-designed with national stakeholders, to evaluate different delivery strategies for optimizing health system delivery of post-discharge malaria…
- Trial name
- PDMC-SL (NCT06601712)
- Testing
- Adherence support strategy A, Adherence support strategy B, Control
- Where
- 2 sites in Benin
- Volunteers
- 648 people
- Sponsor
- Institut de Recherche Clinique du Benin
Preterm Birth, Breastfeeding
Phone Breastfeeding Support for Premature Babies
It was observed that premature babies had the risk of insufficient milk intake and a lower rate of breastfeeding compared to term babies.
- Trial name
- NCT04883866
- Testing
- Telephone Breastfeeding Support Program, Sending a breastfeeding guide for premature babies to the phone of mothers in addition to the routine discharge procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Dental Phobia, Dental Anxiety
"Study of Pain Perception Using Computer-Controlled Versus Conventional Local Anaesthesia in Children Undergoing Molar Extraction
This clinical trial aims to compare pain perception in children during dental procedures when using a computer-controlled local anesthesia device versus a traditional syringe.
- Conditions
- Dental Phobia, Dental Anxiety, Dental Anesthesia, Dental Anesthesia Efficacy
- Trial name
- CCLAD-Pain (NCT07056101)
- Testing
- A conventional dental syringe, GENI High-Speed Injection, GENI Moderate-Speed Injection
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tarek MHD kher al saka amini
Infant, Premature, Respiration, Artificial
Use of NAVA in Intubated Preterm
The present protocol will demonstrate the feasibility and efficacy of a newly developed mode of mechanical ventilation, Neurally Adjusted Ventilatory Assist, commonly known as NAVA.
- Trial name
- NCT00536445
- Testing
- NAVA
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Thrombotic Thrombocytopenic Purpura (TTP)
A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic thrombocytopenic purpura (or TTP for short) is a condition where blood clots form in small blood vessels throughout the body.
- Trial name
- NCT03393975
- Testing
- TAK-755, Standard of care
- Where
- 33 sites in United States, Austria and 7 more
- Volunteers
- 52 people
- Sponsor
- Baxalta now part of Shire
Pregnancy Prevention, Sexual Behavior
Project Legacy Impact Evaluation Study
This study will design and rigorously evaluate the efficacy of Project Legacy, a five week positive youth development intervention to decrease sexual risk for unintended pregnancies and STIs among youth experiencing homelessness…
- Conditions
- Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
- Trial name
- NCT03366636
- Testing
- Project Legacy
- Where
- 12 sites in United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Apnea of Prematurity
Effect of Three-Stair-Position on Improvement of Apnea of Prematurity
The purpose of this study is evaluating the effectiveness of three-stair-position (TSP) on the rate of Apnea of Prematurity (AOP), the feeding performance and the vital signs.
- Trial name
- NCT02346864
- Testing
- Three-stair-position, Head elevated tilt position group
- Volunteers
- 144 people
- Sponsor
- Children's Hospital of Fudan University
Hypothermia in Premature Infants
Multicentre Randomised Controlled Trial of HELP (Heat Loss Prevention) in the Delivery Room
Does polyethylene occlusive wrap applied immediately after delivery to infants born at less than 28 weeks gestation decrease all-cause mortality measured at discharge compared with the standard of care as determined by the…
- Trial name
- HeLP (NCT00607464)
- Testing
- Polyethylene occlusive skin wrap
- Where
- Canada
- Volunteers
- 804 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Cancer
ADT Exercise Trial and Economic Analysis
Prostate Cancer (PC) affects 1 in 7 men. Nearly half of those diagnosed with PC will receive androgen deprivation therapy (ADT) as part of their treatment. ADT is good at managing PC but has many side effects.
- Trial name
- ADTExRCT (NCT02834416)
- Testing
- Supervised Group Exercise, Home Based Exercise
- Where
- 4 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University Health Network, Toronto
Preterm Birth, Feeding Behavior
Preterm Infant Oral Motor Intervention (PIOMI)
The purpose of this research; The aim of this study is to examine the effects of oral motor intervention (PIOMI) and combined kangaroo care applied to preterm babies on weight gain, oral feeding skills, transition to full oral…
- Trial name
- NCT06259604
- Testing
- PIOMI, PIOMI+kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Unintended Pregnancy Prevention
Telemedicine for Contraceptive Counselling- An Open Randomized Controlled Trial
Protocol Summary: Sweden has high unintended pregnancy rates, increasing unmet contraceptive needs, and the highest repeat abortion rate in the European Union.
- Trial name
- Tele-prev (NCT06896539)
- Testing
- Telemedicine, Counselling in person visit
- Volunteers
- 772 people
- Sponsor
- Region Örebro County
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Participants of Longitudinal Cohort Studies, Controls
A Mobile App to Improve Participation in Following-up Cohorts
The main objective is to test the superiority of a newly developed mobile application - RECAP_MyLife - for data collection in cohort studies in order to increase participation in follow-up evaluations.
- Trial name
- NCT04714788
- Testing
- RECAP_MyLife mobile app, Usual data collection methods
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
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