Clinical trials: Bladder
Urinary Bladder Neurogenic
Pharmacokinetics and Safety Study With Alfuzosin in Children and Adolescents With Elevated Detrusor Leak Point Pressure of Neuropathic Etiology
The primary objective is to investigate the pharmacokinetics (PK) of 2 doses of alfuzosin (given as a solution or tablets depending on age) in children and adolescents 2 to 16 years of age with elevated detrusor Leak Point…
- Trial name
- ALFACHIP (NCT00629720)
- Testing
- alfuzosin (SL770499)
- Where
- 2 sites in United States, Serbia
- Volunteers
- 29 people
- Sponsor
- Sanofi
Non Muscle Invasive Bladder Cancer
Comparison of BCG RIVM and Russian Strains for Treating Non-Muscle-Invasive Bladder Cancer (NMIBC)
The goal of this clinical trial is to compare the efficacy and safety of two Bacillus Calmette-Guérin (BCG) substrains (RIVM and Russian) in the treatment of intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC)…
- Trial name
- NCT06767982
- Testing
- Bacillus Calmette-Guerin (BCG)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara University
Vesico-Ureteral Reflux, Filum Terminale Lipoma
Effects of Parental Holding on Pain Response in Young Children During Cystometry
Cystometry is essential for diagnosis and treatment plans by identifying the causes of lower urinary tract symptoms and objectively evaluating bladder functions in diseases such as neurogenic bladder, voiding dysfunction, and…
- Trial name
- NCT05864131
- Testing
- Lying, Holding
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Stage III Bladder Cancer, Stage IV Bladder Cancer
Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium
Randomized phase III trial to compare the effectiveness of immediate adjuvant chemotherapy with that of adjuvant chemotherapy given when the cancer returns in treating patients who have undergone a radical cystectomy for stage…
- Conditions
- Stage III Bladder Cancer, Stage IV Bladder Cancer, Transitional Cell Carcinoma of the Bladder
- Trial name
- NCT00028756
- Testing
- doxorubicin hydrochloride, gemcitabine hydrochloride, vinblastine sulfate
- Volunteers
- 285 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Bladder Cancer, Infections
Infectious Complications After Cystectomy: A Prospective Observational Study
Patients undergoing cystectomy for either oncological or non-oncological indications are prospectively enrolled following informed consent.
- Conditions
- Bladder Cancer, Infections, Infection, Bacterial, Infection, Hospital
- Trial name
- NCT05153694
- Testing
- Cystectomy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Bladder Cancer (BC)
Outcomes of Definitive Radiotherapy for Bladder Cancer
this is an observational study for patients with non metastatic bladder cancer recieving local radical radiotherapy with curative intent recieving radical dose of radiotherapy with or without chemosensitizer
- Trial name
- NCT07503795
- Testing
- Radiotherapy followed by chemotherapy
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Sohag University
Neurogenic Detrusor Overactivity, Overactive Bladder
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron OCAS (Oral Controlled Absorption System) in Pediatric Subjects With Neurogenic Detrusor Overactivity or Overactive Bladder
The purpose of this study is to evaluate the pharmacokinetics as well as the safety and tolerability of mirabegron OCAS tablets after single-dose administration at different dose levels in children and adolescents with NDO or OAB.
- Conditions
- Neurogenic Detrusor Overactivity, Overactive Bladder, Pharmacokinetics of Mirabegron
- Trial name
- NCT02211846
- Testing
- Mirabegron
- Where
- 13 sites in Belgium, Denmark and 3 more
- Volunteers
- 34 people
- Sponsor
- Astellas Pharma Inc
Overactive Bladder
Long-Term Specified Drug Use-results Survey of Betanis Tablets
This study is to evaluate the safety and efficacy of long-term use of Betanis (generic name: mirabegron), and to determine the adherence to treatment with mirabegron.
- Trial name
- NCT01901120
- Testing
- Betanis
- Where
- 8 sites in Japan
- Volunteers
- 1,263 people
- Sponsor
- Astellas Pharma Inc
Bladder Exstrophy
Biomechanical Assessment of Level Gait in Patient's Status Post Bladder Exstrophy
The purpose of this study is to determine whether patients who have undergone exstrophy closure may be at risk for long-term orthopedic issues manifest by gait abnormalities.
- Trial name
- Gait (NCT00863070)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Connecticut Children's Medical Center
Bladder Cancer
Open Versus Robot Assisted Radical Cystectomy With Totally Intracorporeal Urinary Diversion.
This prospective randomized study is designed to provide high level of evidence supporting superiority of robot assisted (RA) versus open (O) radical cystectomy (RC).
- Trial name
- NCT03434132
- Testing
- Open or robotic radical cystectomy
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- Regina Elena Cancer Institute
Bladder Fibrosis
Bladder ARFI (Acoustic Radiation Force Impulse) Study
Urinary bladder fibrosis (thickening and scarring) is fairly uncommon in children. Traditionally, the presence of urinary bladder fibrosis has been confirmed directly with bladder biopsy or using urodynamic testing.
- Trial name
- NCT01781832
- Testing
- ARFI-Derived Shear Wave Velocities
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Urinary Tract Infections
Gentamicin Bladder Instillation Trial
Recurrent UTIs are common among patients on IC. These create significant patient morbidity and healthcare burden. In desperation, many physicians prescribe prophylactic oral or intravesical antibiotics.
- Trial name
- NCT01884467
- Testing
- Gentamicin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Gillette Children's Specialty Healthcare
Urinary Tract Infections
Bladder Stimulation Technique for Clean Catch Urine Collection in Infants
Urinary tract infection is the most common serious bacterial infection among infants. Bladder catheterization is considered the gold standard for diagnosis, yet is painful and invasive.
- Trial name
- NCT03174834
- Testing
- Bladder Stimulation technique
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Michigan
Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis
Laparoscopic Cholecystectomy Using Airseal in Children
The goal of this observational study is to compare the use of Airseal versus a standard insufflation, in children who underwent laparoscopic cholecystectomy, between January 2021 and December 2022.
- Conditions
- Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis, Pancreatitis Due to Gallstones, Child, Only
- Trial name
- VBAS (NCT06734507)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Destinval Christelle
Bladder Cancer
Intravesical Thermochemotherapy With Mitomycin-c
To investigate effect of intravesical mitomycin-C(MMC) applied with bladder wall thermotherapy system on reccurrence and progression status of intermediate and high risk non muscle invasive bladder cancer
- Trial name
- NCT03694535
- Testing
- bladder wall thermotherapy with Mitomycin-c
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- TC Erciyes University
Overactive Bladder, Vitamin D Deficiency
The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D Deficiency
The primary aim of this study is to evaluate the role of three specific urinary proteins-RhoA, Nerve Growth Factor (NGF), and Brain-Derived Neurotrophic Factor (BDNF)-as potential biomarkers for the diagnosis and follow-up of…
- Trial name
- NCT07513363
- Testing
- Urotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tarik Emre Sener
Neurogenic Bladder Due to Spina Bifida (Disorder)
Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder
The objective of the study is to determine whether single-use polyvinylchloride (PVC) catheters reduce urinary tract infections (UTI) compared to reused PVC catheters for patients with neurogenic bladder due to spina bifida that…
- Trial name
- Catheters (NCT03424499)
- Testing
- Single-use catheter, Reused catheter, Urine culture
- Volunteers
- 113 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Spinal Dysraphism
Determining Developmental and Clinical Markers Affecting Urinary Function of Children With Spinal Dysraphism
To identify developmental and clinical biomarkers that affect urinary incontinence at the ages of 5, 7, and 10 according to different neuro-urological clinical factors.
- Trial name
- NCT05962086
- Where
- 6 sites in South Korea
- Volunteers
- 1,500 people
- Sponsor
- Seoul National University Hospital
Superficial Bladder Cancer t1a
Skipping BCG for T1a Urinary Bladder Tumor.
Bladder cancer is the most common malignancy involving theurinary system and the ninth most common malignancy worldwide .In Egypt, the urinary bladder cancer accounted for about 31% of the total incidence of cancers that…
- Trial name
- NCT04298073
- Volunteers
- 43 people
- Sponsor
- Assiut University