Clinical trials: Bladder
Overactive Bladder (OAB), Pharmacokinetics of Mirabegron
A Study to Evaluate Mirabegron in Pediatric Participants From 5 to Less Than 18 Years of Age With Overactive Bladder (OAB)
The purpose of this study was to evaluate the efficacy of mirabegron in children (5 to < 12 years of age) with OAB. This study will also evaluated the safety and tolerability of mirabegron in pediatric participants with OAB and…
- Trial name
- Dolphin (NCT04641975)
- Testing
- Mirabegron
- Where
- 15 sites in Belgium, France and 8 more
- Volunteers
- 26 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Bladder Cancer
Aschistosoma Haematobiumspecific microRNAas a Tumor Marker for Early Diagnosis and Prognosis of Bilharzial Bladder Cancer in Eygpt
miRNAs have been detected in different bodily fluids, which suggests significant potential, such as their use as biomarkers in diagnostics and prognostics.
- Trial name
- NCT05697224
- Testing
- urinary micro RNA detection
- Volunteers
- 50 people
- Sponsor
- Sohag University
Laser-Induced Scar, Breast Cancer
Laser Treatment of Genito-urinary Syndrome in Women
Women with genitourinary syndrome of menopause, overactive bladder, with breast or endometrial cancer are randomized to either laser treatment og sham treatment for 3 months.
- Conditions
- Laser-Induced Scar, Breast Cancer, Endometrial Cancer, Menopause
- Trial name
- NCT03238053
- Testing
- Vaginal laser treatment, laser system
- Where
- Denmark
- Sponsor
- Herning Hospital
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Combination Chemotherapy Following Surgery in Treating Patients With Urinary Tract Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00028860
- Testing
- filgrastim, carboplatin, gemcitabine hydrochloride
- Where
- United States
- Sponsor
- Tulane University Health Sciences Center
Temperature Monitoring
Non-invasive Temperature Monitoring in Pediatric Intensive Care Patients Requiring Targeted Temperature Management: Evaluation of Temple Touch Pro
The purpose of this study is to evaluate the Temple Touch Pro (TTP) in Pediatric Intensive Care Unity (PICU) patients requiring targeted temperature control.
- Trial name
- NCT07507396
- Testing
- Temple Touch Pro
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Detrusor Overactivity
Ultrasonographic Bladder Wall Thickness and Different Forms of Detrusor Overactivity
In the last decade, several authors proposed ultrasound measurement of Bladder wall thickness (BWT) for the screening of the voiding dysfunction and of the detrusor overactivity (DO).
- Trial name
- NCT01003457
- Testing
- ultrasonography
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Overactive Bladder Syndrome, Neuropathic Bladder
Oxybutynin for Post-surgical Bladder Pain and Urgency
Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.
- Trial name
- NCT03952299
- Testing
- Oxybutynin Transdermal Patch, Oral Oxybutynin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid
Ejection Fraction of Normal Gall Bladder on Ultrasonography in Patients With Biliary Colic: Is it a Predictor of Cholecystectomy?
In this study investigators aim to evaluate gallbladder ejection fraction as a predictor for cholecystectomy.
- Conditions
- Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid, Acalculous Cholecystitis
- Trial name
- NCT05587933
- Testing
- cholecystectomy, Antispasmodic
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pyelonephritis, Renal Scars
A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux
The aim of this study is to assess the effectiveness of antibiotic prophylaxis in preventing pyelonephritis and in avoiding the appearance of new scars in a sample of children under 36 months with vesico-ureteral reflux (VUR).
- Trial name
- NCT00382343
- Testing
- Sulfamethoxazole/trimethoprim
- Where
- 7 sites in Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS Burlo Garofolo
Vesico-Ureteral Reflux, Filum Terminale Lipoma
Effects of Parental Holding on Pain Response in Young Children During Cystometry
Cystometry is essential for diagnosis and treatment plans by identifying the causes of lower urinary tract symptoms and objectively evaluating bladder functions in diseases such as neurogenic bladder, voiding dysfunction, and…
- Trial name
- NCT05864131
- Testing
- Lying, Holding
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Overactive Bladder, Pediatric Disorder
Efficacy and Mechanism of High-Dose Vitamin D Supplementation in Pediatric OAB-Dry: A Randomized Clinical Trial Integrating Urinary Myelin Basic Protein as a Theranostic Biomarker
The aim of this study is to give children with dry OAB: (1) Standard behavioral therapy combined with classical anticholinergic drugs (Solinaxine), or (2) standard behavioral therapy combined with short-term high-dose exogenous…
- Trial name
- NCT06489951
- Testing
- Solifenacin, vitamin D, Standard behavioral therapy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xing Liu
Overactive Bladder, Multiple Sclerosis
Transcutaneous Tibial Nerve Stimulation of Patients With Overactive Bladder (OAB) Syndrome
Tibial nerve stimulation (TNS) has been recognised as a safe and effective treatment for the management of overactive bladder (OAB) symptoms.
- Trial name
- NCT02790307
- Testing
- The Geko
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Neurogenic Incontinence, Dysfunctional Voiding
Treatment of Neurogenic Incontinence by Surgery to Cut the Filum Terminale
The target population of this study is children with primary or secondary daytime urinary incontinence, who have failed to improve adequately despite compliance with at least 6 months of standard medical therapy.
- Trial name
- NICNOC (NCT01465581)
- Testing
- Division of the filum terminal
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nemours Children's Clinic
Urinary Dysfunction, Lower Urinary Tract Symptoms
School-Based Bladder Health Intervention
The aim of this study is to promote healthy bladder behaviors among school children. We hypothesize that a combination of bladder health education and awareness events, additional resources such as a water station to support…
- Conditions
- Urinary Dysfunction, Lower Urinary Tract Symptoms, Urinary Tract Infections, Urinary Tract Infections in Children
- Trial name
- NCT06273098
- Testing
- Bladder Health Education
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Bacteriuria
Bacteriuria Eradication Through Probiotics
Many children who catheterize their bladders because of spina bifida or other neurologic disorders have bacteriuria. This can lead to urinary tract infections by bacteria from the gut which colonize the vagina and are carried…
- Trial name
- BERP (NCT00717600)
- Testing
- Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Neurogenic Bladder
Botox Versus Oxybutynin as First Line Treatment for the Poorly Compliant Pediatric Neurogenic Bladder
The purpose of this study is to investigate the use of Botulinum Toxin A as primary therapy for children with neurogenic bladder due to spina bifida and compare results with standard oral oxybutynin therapy.
- Trial name
- NCT01716624
- Testing
- Oxybutynin, Botulinum Toxin A injection
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Vesico-Ureteral Reflux
Evaluation of the Efficiency of Autologous Adipocytes Graft in Endoscopic Treatment in Vesico-Renal Reflux in Children
Urinary tract infection (UTI) is a common problem in childhood associated with vesico-renal reflux (VRR) in 25-40% of children. A persistent VRR and repeated pyelonephritis may predispose to renal scarring and chronic renal…
- Trial name
- NCT00367159
- Testing
- endoscopic treatment of vesico-renal reflux
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Urologic Surgical Procedures, Urinary Bladder, Neurogenic
Pediatric Urology Recovery After Surgery Endeavor (PURSUE)
The purpose of this research study is to evaluate an Enhanced Recovery After Surgery (ERAS) protocol in children and young adults undergoing urologic reconstructive surgery.
- Conditions
- Urologic Surgical Procedures, Urinary Bladder, Neurogenic, Urinary Bladder Diseases
- Trial name
- NCT03245242
- Testing
- Enhanced Recovery after Surgery, Historical usual surgical care
- Where
- 7 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
BK Virus Infection, Hemorrhagic Cystitis
Study to Evaluate Viralym-M (ALVR105) for the Treatment of Virus-Associated Hemorrhagic Cystitis (HC)
Study to Evaluate Viralym-M (ALVR105) for the Treatment of Virus-Associated Hemorrhagic Cystitis (HC).
- Trial name
- NCT04390113
- Testing
- Posoleucel (ALVR105)
- Where
- 56 sites in United States, France and 5 more
- Volunteers
- 97 people
- Sponsor
- AlloVir
VUR - Vesicoureteric Reflux
Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
The purpose of this study is to examine the applicability of contrast enhanced voiding ultrasonography in diagnosing vesicoureteral reflux (VUR) in pediatric patients compared to direct isotope cystography.
- Trial name
- NCT06138080
- Testing
- Contrast-enhanced voiding ultrasonography (CEVUS), Direct isotope cystography
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital